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Qian Xu

Qian Xu contributes to research discovery and scholarly infrastructure.

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Published work

9 published item(s)

preprint2026arXiv

A Breast Vision Pathology Foundation Model for Real-world Clinical Utility

Pathology foundation models have shown strong retrospective performance, but whether such systems can support clinically relevant use remains unclear. This challenge is particularly important in breast cancer, where pathological assessment serves as the gold standard for diagnosis and guides treatment planning, surgical decision-making and risk stratification across pre-, intra- and post-operative stages. Here we present \textbf{BRAVE}, a breast-adaptive pathology foundation model developed and evaluated using a total resource of 101,638 breast whole-slide images from 32 sources across Asia, Europe and North America. We assessed BRAVE across 34 tasks in 82 cohorts spanning pre-operative biopsy, intra-operative frozen section and post-operative resection, using an evidence chain comprising retrospective benchmarking, clinically challenging scenarios, workflow-oriented clinical impact simulations, prospective observational validation with the thresholds locked in the retrospective cohorts and crossover pathologist-AI interaction studies. Across these settings, BRAVE supported practical roles in the clinical workflow, including safe exclusion of low-risk cases from routine review, AI-assisted second-review rescue of initially missed positives and prioritization of cases for further assessment. In prospective validation across three centres, BRAVE excluded 76.9% of negative biopsy cases (NPV 0.953) and 70.1% of negative frozen-section cases (NPV 0.973), and triaged 78.8% of post-operative subtyping cases as high-confidence clear-cut cases (NPV 1.000). In reader studies, AI assistance improved balanced accuracy from 88.5% to 95.1% (OR 3.14, P<0.001), with better efficiency, confidence and inter-rater agreement. BRAVE-derived scores also independently predicted disease-free survival (adjusted HR 4.79, P<0.001) and overall survival (adjusted HR 8.14, P<0.001).

preprint2022arXiv

An Efficient Industrial Federated Learning Framework for AIoT: A Face Recognition Application

Recently, the artificial intelligence of things (AIoT) has been gaining increasing attention, with an intriguing vision of providing highly intelligent services through the network connection of things, leading to an advanced AI-driven ecology. However, recent regulatory restrictions on data privacy preclude uploading sensitive local data to data centers and utilizing them in a centralized approach. Directly applying federated learning algorithms in this scenario could hardly meet the industrial requirements of both efficiency and accuracy. Therefore, we propose an efficient industrial federated learning framework for AIoT in terms of a face recognition application. Specifically, we propose to utilize the concept of transfer learning to speed up federated training on devices and further present a novel design of a private projector that helps protect shared gradients without incurring additional memory consumption or computational cost. Empirical studies on a private Asian face dataset show that our approach can achieve high recognition accuracy in only 20 communication rounds, demonstrating its effectiveness in prediction and its efficiency in training.

preprint2022arXiv

Stabilizing a Bosonic Qubit using Colored Dissipation

Protected qubits such as the 0-$π$ qubit, and bosonic qubits including cat qubits and GKP qubits offer advantages for fault-tolerance. Some of these protected qubits (e.g., 0-$π$ qubit and Kerr cat qubit) are stabilized by Hamiltonians which have (near-)degenerate ground state manifolds with large energy-gaps to the excited state manifolds. Without dissipative stabilization mechanisms the performance of such energy-gap-protected qubits can be limited by leakage to excited states. Here, we propose a scheme for dissipatively stabilizing an energy-gap-protected qubit using colored (i.e., frequency-selective) dissipation without inducing errors in the ground state manifold. Concretely we apply our colored dissipation technique to Kerr cat qubits and propose colored Kerr cat qubits which are protected by an engineered colored single-photon loss. When applied to the Kerr cat qubits our scheme significantly suppresses leakage-induced bit-flip errors (which we show are a limiting error mechanism) while only using linear interactions. Beyond the benefits to the Kerr cat qubit we also show that our frequency-selective loss technique can be applied to a broader class of protected qubits.

preprint2022arXiv

Uncertainty-based Network for Few-shot Image Classification

The transductive inference is an effective technique in the few-shot learning task, where query sets update prototypes to improve themselves. However, these methods optimize the model by considering only the classification scores of the query instances as confidence while ignoring the uncertainty of these classification scores. In this paper, we propose a novel method called Uncertainty-Based Network, which models the uncertainty of classification results with the help of mutual information. Specifically, we first data augment and classify the query instance and calculate the mutual information of these classification scores. Then, mutual information is used as uncertainty to assign weights to classification scores, and the iterative update strategy based on classification scores and uncertainties assigns the optimal weights to query instances in prototype optimization. Extensive results on four benchmarks show that Uncertainty-Based Network achieves comparable performance in classification accuracy compared to state-of-the-art method.

preprint2022arXiv

WrapperFL: A Model Agnostic Plug-in for Industrial Federated Learning

Federated learning, as a privacy-preserving collaborative machine learning paradigm, has been gaining more and more attention in the industry. With the huge rise in demand, there have been many federated learning platforms that allow federated participants to set up and build a federated model from scratch. However, exiting platforms are highly intrusive, complicated, and hard to integrate with built machine learning models. For many real-world businesses that already have mature serving models, existing federated learning platforms have high entry barriers and development costs. This paper presents a simple yet practical federated learning plug-in inspired by ensemble learning, dubbed WrapperFL, allowing participants to build/join a federated system with existing models at minimal costs. The WrapperFL works in a plug-and-play way by simply attaching to the input and output interfaces of an existing model, without the need of re-development, significantly reducing the overhead of manpower and resources. We verify our proposed method on diverse tasks under heterogeneous data distributions and heterogeneous models. The experimental results demonstrate that WrapperFL can be successfully applied to a wide range of applications under practical settings and improves the local model with federated learning at a low cost.

preprint2021arXiv

Band-Notched Frequency-Selective Absorber with Polarization Rotation Function

This paper presents the theoretical analysis, design, simulations, and experimental verification of a novel band-notched frequency-selective absorber (BFSA) with polarization rotation function and absorption out-of-band. The BFSA consists of multiple layers including one lossy layer, one polarization-rotary layer and an air layer. The lossy layer is loaded with lumped resistances for obtaining a wide absorption band. A new four-port equivalent circuit model (ECM) with lossy layer is developed for providing theoretical analysis. The BFSA realizes -0.41dB cross-polarization reflection at 4.5GHz. In the upper and lower bands, the BFSA realizes a broad absorption function from 2.2GHz to 4.1GHz and 5.03GHz to 6.5GHz. The fractional bandwidth of co-polarization reflection is 98.8% with 10dB reflection reduction. The full-wave simulation, ECM, and experimental measurements are conducted to validate the polarization conversion of the band-notched absorbers, and good agreement between theory and measurement results is observed.

preprint2020arXiv

Federated Deep Reinforcement Learning

In deep reinforcement learning, building policies of high-quality is challenging when the feature space of states is small and the training data is limited. Despite the success of previous transfer learning approaches in deep reinforcement learning, directly transferring data or models from an agent to another agent is often not allowed due to the privacy of data and/or models in many privacy-aware applications. In this paper, we propose a novel deep reinforcement learning framework to federatively build models of high-quality for agents with consideration of their privacies, namely Federated deep Reinforcement Learning (FedRL). To protect the privacy of data and models, we exploit Gausian differentials on the information shared with each other when updating their local models. In the experiment, we evaluate our FedRL framework in two diverse domains, Grid-world and Text2Action domains, by comparing to various baselines.

preprint2020arXiv

MxPool: Multiplex Pooling for Hierarchical Graph Representation Learning

How to utilize deep learning methods for graph classification tasks has attracted considerable research attention in the past few years. Regarding graph classification tasks, the graphs to be classified may have various graph sizes (i.e., different number of nodes and edges) and have various graph properties (e.g., average node degree, diameter, and clustering coefficient). The diverse property of graphs has imposed significant challenges on existing graph learning techniques since diverse graphs have different best-fit hyperparameters. It is difficult to learn graph features from a set of diverse graphs by a unified graph neural network. This motivates us to use a multiplex structure in a diverse way and utilize a priori properties of graphs to guide the learning. In this paper, we propose MxPool, which concurrently uses multiple graph convolution/pooling networks to build a hierarchical learning structure for graph representation learning tasks. Our experiments on numerous graph classification benchmarks show that our MxPool has superiority over other state-of-the-art graph representation learning methods.

preprint2020arXiv

Quantum wave-particle superposition in a delayed-choice experiment

Wave-particle duality epitomizes the counterintuitive character of quantum physics. A striking illustration is the quantum delay-choice experiment, which is based on Wheeler&#39;s classic delayed-choice gedanken experiment, but with the addition of a quantum-controlled device enabling wave-to-particle transitions. Here we realize a quantum delayed-choice experiment in which we control the wave and the particle states of photons and in particular the phase between them, thus directly establishing the created quantum nature of the wave-particle. We generate three-photon entangled states and inject one photon into a Mach--Zehnder interferometer embedded in a 187-m-long two-photon Hong-Ou-Mandel interferometer. The third photon is sent 141m away from the interferometers and remotely prepares a two-photon quantum gate according to independent active choices under Einstein locality conditions. We have realized transitions between wave and particle states in both classical and quantum scenarios, and therefore tests of the complementarity principle that go fundamentally beyond earlier implementations.