BZPEERReading, trust and collaboration for research
Menu

Discover

GraphFollow connections around a paper, topic or saved view.

Workspaces

HomePick up where your research flow left off.InboxHandle requests, replies and notifications from one place.CollectionsCurate reading lists, evidence sets and shareable dossiers.ResearchSee your private provenance graph, trail and imports.CollaborationMove from discovery into focused discussion rooms.PublishDraft, preview and publish full-text research articles.

Network

ExpertsFind specialists worth following or asking for help.CommunitiesJoin research circles organized around shared work.PartnersSee external organizations active around the same topics.

Opportunities

ListingsBrowse roles, calls and collaborations with clearer fit signals.

Account

Log inReturn to your reading and collaboration workspace.Create accountStart saving work, following people and joining teams.
Log inCreate account

Researcher profile

Qian Li

Qian Li contributes to research discovery and scholarly infrastructure.

ResearcherAffiliation not importedOpen to collaborate
Machine LearningComputer VisionArtificial Intelligencecond-mat.mtrl-scicond-mat.mes-halleess.IVComputation and Languagecond-mat.supr-conDistributed, Parallel, and Cluster Computingphysics.app-phphysics.opticsApplicationsCryptography and SecurityDatabasesInformation Retrievalmath.OCNeural and Evolutionary ComputingSocial and Information NetworksComputational ComplexityDigital Librariesgr-qcGraphicsHuman-Computer Interactionnlin.PSphysics.comp-phphysics.flu-dynSoftware Engineering

Trust snapshot

Quick read

Trust 21 - EmergingVerification L1Unclaimed author
45works
0followers
27topics
4close collaborators

Actions

Decide how to stay connected

Follow researcher0

Identity and collaboration

How to connect with this researcher

Claiming links this public author record to a researcher profile and unlocks direct collaboration workflows.

Log in to claim

Direct collaboration

Open a focused conversation when the fit is right

Claim this author entity first to unlock direct invitations.

Research graph

See the researcher in context

Open full explorer

Inspect adjacent work, topics, institutions and collaborators without jumping out to a separate graph page.

Building this graph slice

BZPEER is loading the nearby papers, people, topics and institutions for this page.

Published work

45 published item(s)

preprint2026arXiv

Delineating Knowledge Boundaries for Honest Large Vision-Language Models

Large Vision-Language Models (VLMs) have achieved remarkable multimodal performance yet remain prone to factual hallucinations, particularly in long-tail or specialized domains. Moreover, current models exhibit a weak capacity to refuse queries that exceed their parametric knowledge. In this paper, we propose a systematic framework to enhance the refusal capability of VLMs when facing such unknown questions. We first curate a model-specific "Visual-Idk" (Visual-I don't know) dataset, leveraging multi-sample consistency probing to distinguish between known and unknown facts. We then align the model using supervised fine-tuning followed by preference-aware optimization (e.g., DPO, ORPO) to effectively delineate its knowledge boundaries. Results on the Visual-Idk dataset show our method improves the Truthful Rate from 57.9\% to 67.3\%. Additionally, internal probing also demonstrates that the model genuinely recognizes its boundaries instead of just memorizing refusal patterns. Our framework further generalizes to out-of-distribution medical and perceptual domains, providing a robust path toward more trustworthy and prudent visual assistants.

0 citations0 reviewsNo code linkedOpen access
preprint2024arXiv

Text-Video Retrieval via Variational Multi-Modal Hypergraph Networks

Text-video retrieval is a challenging task that aims to identify relevant videos given textual queries. Compared to conventional textual retrieval, the main obstacle for text-video retrieval is the semantic gap between the textual nature of queries and the visual richness of video content. Previous works primarily focus on aligning the query and the video by finely aggregating word-frame matching signals. Inspired by the human cognitive process of modularly judging the relevance between text and video, the judgment needs high-order matching signal due to the consecutive and complex nature of video contents. In this paper, we propose chunk-level text-video matching, where the query chunks are extracted to describe a specific retrieval unit, and the video chunks are segmented into distinct clips from videos. We formulate the chunk-level matching as n-ary correlations modeling between words of the query and frames of the video and introduce a multi-modal hypergraph for n-ary correlation modeling. By representing textual units and video frames as nodes and using hyperedges to depict their relationships, a multi-modal hypergraph is constructed. In this way, the query and the video can be aligned in a high-order semantic space. In addition, to enhance the model's generalization ability, the extracted features are fed into a variational inference component for computation, obtaining the variational representation under the Gaussian distribution. The incorporation of hypergraphs and variational inference allows our model to capture complex, n-ary interactions among textual and visual contents. Experimental results demonstrate that our proposed method achieves state-of-the-art performance on the text-video retrieval task.

0 citations0 reviewsNo code linkedOpen access
preprint2023arXiv

Multi-spatial Multi-temporal Air Quality Forecasting with Integrated Monitoring and Reanalysis Data

Accurate air quality forecasting is crucial for public health, environmental monitoring and protection, and urban planning. However, existing methods fail to effectively utilize multi-scale information, both spatially and temporally. Spatially, there is a lack of integration between individual monitoring stations and city-wide scales. Temporally, the periodic nature of air quality variations is often overlooked or inadequately considered. To address these limitations, we present a novel Multi-spatial Multi-temporal air quality forecasting method based on Graph Convolutional Networks and Gated Recurrent Units (M2G2), bridging the gap in air quality forecasting across spatial and temporal scales. The proposed framework consists of two modules: Multi-scale Spatial GCN (MS-GCN) for spatial information fusion and Multi-scale Temporal GRU(MT-GRU) for temporal information integration. In the spatial dimension, the MS-GCN module employs a bidirectional learnable structure and a residual structure, enabling comprehensive information exchange between individual monitoring stations and the city-scale graph. Regarding the temporal dimension, the MT-GRU module adaptively combines information from different temporal scales through parallel hidden states. Leveraging meteorological indicators and four air quality indicators, we present comprehensive comparative analyses and ablation experiments, showcasing the higher accuracy of M2G2 in comparison to nine currently available advanced approaches across all aspects. The improvements of M2G2 over the second-best method on RMSE of the 24h/48h/72h are as follows: PM2.5: (7.72%, 6.67%, 10.45%); PM10: (6.43%, 5.68%, 7.73%); NO2: (5.07%, 7.76%, 16.60%); O3: (6.46%, 6.86%, 9.79%). Furthermore, we demonstrate the effectiveness of each module of M2G2 by ablation study.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Atomically engineered cobaltite layers for robust ferromagnetism

Emergent phenomena at heterointerfaces are directly associated with the bonding geometry of adjacent layers. Effective control of accessible parameters, such as the bond length and bonding angles, offers an elegant method to tailor competing energies of the electronic and magnetic ground states. In this study, we construct unit thick syntactic layers of cobaltites within a strongly tilted octahedral matrix via atomically precise synthesis. The octahedral tilt patterns of adjacent layers propagate into cobaltites, leading to a continuation of octahedral tilting while maintaining significant misfit tensile strain. These effects induce severe rumpling within an atomic plane of neighboring layers triggers the electronic reconstruction between the splitting orbitals. First-principles calculations reveal that the cobalt ions transits to a higher spin state level upon octahedral tilting, resulting in robust ferromagnetism in ultrathin cobaltites. This work demonstrates a design methodology for fine-tuning the lattice and spin degrees of freedom in correlated quantum heterostructures by exploiting epitaxial geometric engineering.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Braiding lateral morphotropic grain boundary in homogeneitic oxides

Interfaces formed by correlated oxides offer a critical avenue for discovering emergent phenomena and quantum states. However, the fabrication of oxide interfaces with variable crystallographic orientations and strain states integrated along a film plane is extremely challenge by conventional layer-by-layer stacking or self-assembling. Here, we report the creation of morphotropic grain boundaries (GBs) in laterally interconnected cobaltite homostructures. Single-crystalline substrates and suspended ultrathin freestanding membranes provide independent templates for coherent epitaxy and constraint on the growth orientation, resulting in seamless and atomically sharp GBs. Electronic states and magnetic behavior in hybrid structures are laterally modulated and isolated by GBs, enabling artificially engineered functionalities in the planar matrix. Our work offers a simple and scalable method for fabricating unprecedented innovative interfaces through controlled synthesis routes as well as provides a platform for exploring potential applications in neuromorphics, solid state batteries, and catalysis.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Causal Disentanglement for Semantics-Aware Intent Learning in Recommendation

Traditional recommendation models trained on observational interaction data have generated large impacts in a wide range of applications, it faces bias problems that cover users' true intent and thus deteriorate the recommendation effectiveness. Existing methods tracks this problem as eliminating bias for the robust recommendation, e.g., by re-weighting training samples or learning disentangled representation. The disentangled representation methods as the state-of-the-art eliminate bias through revealing cause-effect of the bias generation. However, how to design the semantics-aware and unbiased representation for users true intents is largely unexplored. To bridge the gap, we are the first to propose an unbiased and semantics-aware disentanglement learning called CaDSI (Causal Disentanglement for Semantics-Aware Intent Learning) from a causal perspective. Particularly, CaDSI explicitly models the causal relations underlying recommendation task, and thus produces semantics-aware representations via disentangling users true intents aware of specific item context. Moreover, the causal intervention mechanism is designed to eliminate confounding bias stemmed from context information, which further to align the semantics-aware representation with users true intent. Extensive experiments and case studies both validate the robustness and interpretability of our proposed model.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Coexistence of extended flat band and Kekulé order in Li-intercalated graphene

Doping graphene near the 1/4 filling to shift the extended flat band and van Hove singularity below E$_F$ has been highly desirable. Here we report the experimental observation of an extended flat band below E$_F$ in Li-intercalated graphene. Strong electron-phonon interaction is clearly identified by notable kinks in the band dispersion. Moreover, the evolution of the band structure upon Li intercalation shows that the extended flat band and the Kekulé order emerge simultaneously. Our work provides opportunities for investigating flat band related instabilities and its interplay with the Kekulé order

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

CoSCL: Cooperation of Small Continual Learners is Stronger than a Big One

Continual learning requires incremental compatibility with a sequence of tasks. However, the design of model architecture remains an open question: In general, learning all tasks with a shared set of parameters suffers from severe interference between tasks; while learning each task with a dedicated parameter subspace is limited by scalability. In this work, we theoretically analyze the generalization errors for learning plasticity and memory stability in continual learning, which can be uniformly upper-bounded by (1) discrepancy between task distributions, (2) flatness of loss landscape and (3) cover of parameter space. Then, inspired by the robust biological learning system that processes sequential experiences with multiple parallel compartments, we propose Cooperation of Small Continual Learners (CoSCL) as a general strategy for continual learning. Specifically, we present an architecture with a fixed number of narrower sub-networks to learn all incremental tasks in parallel, which can naturally reduce the two errors through improving the three components of the upper bound. To strengthen this advantage, we encourage to cooperate these sub-networks by penalizing the difference of predictions made by their feature representations. With a fixed parameter budget, CoSCL can improve a variety of representative continual learning approaches by a large margin (e.g., up to 10.64% on CIFAR-100-SC, 9.33% on CIFAR-100-RS, 11.45% on CUB-200-2011 and 6.72% on Tiny-ImageNet) and achieve the new state-of-the-art performance.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Delineating complex ferroelectric domain structures via second harmonic generation spectral imaging

Understanding the mechanisms and spatial correlations of crystallographic symmetry breaking in ferroelectric materials is essential to tuning their functional properties. While optical second harmonic generation (SHG) has long been utilized in ferroelectric studies, its capability for probing complex polar materials has yet to be fully realized. Here, we develop a SHG spectral imaging method implemented on a home-designed laser-scanning SHG microscope, and demonstrate its application for a model system of (K,Na)NbO3 single crystals. Supervised model fitting analysis produces comprehensive information about the polarization vector orientations and relative fractions of constituent domain variants as well as their thermal evolution across the polymorphic phase transitions. We observe an unexpected persistence of the orthorhombic phase at low temperatures, pointing to the phase competitions. Besides, we show that unsupervised matrix decomposition analysis can quickly and faithfully reveal domain configurations without a priori knowledge about specific material systems. The SHG spectral imaging method can be readily extended to other ferroelectric materials with potentials to be further enhanced.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Epitaxial stabilization of an orthorhombic Mg-Ti-O superconductor

The family of titanium oxide superconductors exhibits many intriguing phenomena comparable to cuprates and iron pnictides/chalcogenides, and thus provides an ideal platform to contrastively study the unconventional pairing mechanism of high-temperature superconductors. Here, we successfully deposit superconducting Mg-Ti-O films on MgAl$_2$O$_4$ substrates with three principal orientations by ablating a MgTi$_2$O$_4$ target. Particularly, it is striking to observed that a single-crystalline film of an unintended structure has been grown on the (011)-oriented substrate, with the highest zero resistance transition temperature ($T_{\mathrm{c}0}$) of 5.0 K among them. The film has a highly reduced Mg/Ti ratio and an orthorhombic Ti$_9$O$_{10}$-like structure (denoted as Mg: Ti$_9$O$_{10}$), demonstrated by further characterizations of chemical composition and structure. Such a structure is unstable in bulk but favorable to be epitaxially stabilized on the (011)-surface of MgAl$_2$O$_4$ due to a relatively small strain at the formed interface. An isotropic upper critical field ($B_{\mathrm{c}2}$) up to 13.7 T that breaks the Pauli limit is observed in the Mg: Ti$_9$O$_{10}$ film, analogous to other superconducting titanium oxides. The similarity points to a common origin for the superconductivity in the family, which will provide valuable opinions for the mechanism of unconventional superconductivity in transition metal compounds.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Event Extraction by Associating Event Types and Argument Roles

Event extraction (EE), which acquires structural event knowledge from texts, can be divided into two sub-tasks: event type classification and element extraction (namely identifying triggers and arguments under different role patterns). As different event types always own distinct extraction schemas (i.e., role patterns), previous work on EE usually follows an isolated learning paradigm, performing element extraction independently for different event types. It ignores meaningful associations among event types and argument roles, leading to relatively poor performance for less frequent types/roles. This paper proposes a novel neural association framework for the EE task. Given a document, it first performs type classification via constructing a document-level graph to associate sentence nodes of different types, and adopting a graph attention network to learn sentence embeddings. Then, element extraction is achieved by building a universal schema of argument roles, with a parameter inheritance mechanism to enhance role preference for extracted elements. As such, our model takes into account type and role associations during EE, enabling implicit information sharing among them. Experimental results show that our approach consistently outperforms most state-of-the-art EE methods in both sub-tasks. Particularly, for types/roles with less training data, the performance is superior to the existing methods.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

FedMCSA: Personalized Federated Learning via Model Components Self-Attention

Federated learning (FL) facilitates multiple clients to jointly train a machine learning model without sharing their private data. However, Non-IID data of clients presents a tough challenge for FL. Existing personalized FL approaches rely heavily on the default treatment of one complete model as a basic unit and ignore the significance of different layers on Non-IID data of clients. In this work, we propose a new framework, federated model components self-attention (FedMCSA), to handle Non-IID data in FL, which employs model components self-attention mechanism to granularly promote cooperation between different clients. This mechanism facilitates collaboration between similar model components while reducing interference between model components with large differences. We conduct extensive experiments to demonstrate that FedMCSA outperforms the previous methods on four benchmark datasets. Furthermore, we empirically show the effectiveness of the model components self-attention mechanism, which is complementary to existing personalized FL and can significantly improve the performance of FL.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Forestry digital twin with machine learning in Landsat 7 data

Modeling forests using historical data allows for more accurately evolution analysis, thus providing an important basis for other studies. As a recognized and effective tool, remote sensing plays an important role in forestry analysis. We can use it to derive information about the forest, including tree type, coverage and canopy density. There are many forest time series modeling studies using statistic values, but few using remote sensing images. Image prediction digital twin is an implementation of digital twin, which aims to predict future images bases on historical data. In this paper, we propose an LSTM-based digital twin approach for forest modeling, using Landsat 7 remote sensing image within 20 years. The experimental results show that the prediction twin method in this paper can effectively predict the future images of study area.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

How Does Knowledge Graph Embedding Extrapolate to Unseen Data: A Semantic Evidence View

Knowledge Graph Embedding (KGE) aims to learn representations for entities and relations. Most KGE models have gained great success, especially on extrapolation scenarios. Specifically, given an unseen triple (h, r, t), a trained model can still correctly predict t from (h, r, ?), or h from (?, r, t), such extrapolation ability is impressive. However, most existing KGE works focus on the design of delicate triple modeling function, which mainly tells us how to measure the plausibility of observed triples, but offers limited explanation of why the methods can extrapolate to unseen data, and what are the important factors to help KGE extrapolate. Therefore in this work, we attempt to study the KGE extrapolation of two problems: 1. How does KGE extrapolate to unseen data? 2. How to design the KGE model with better extrapolation ability? For the problem 1, we first discuss the impact factors for extrapolation and from relation, entity and triple level respectively, propose three Semantic Evidences (SEs), which can be observed from train set and provide important semantic information for extrapolation. Then we verify the effectiveness of SEs through extensive experiments on several typical KGE methods. For the problem 2, to make better use of the three levels of SE, we propose a novel GNN-based KGE model, called Semantic Evidence aware Graph Neural Network (SE-GNN). In SE-GNN, each level of SE is modeled explicitly by the corresponding neighbor pattern, and merged sufficiently by the multi-layer aggregation, which contributes to obtaining more extrapolative knowledge representation. Finally, through extensive experiments on FB15k-237 and WN18RR datasets, we show that SE-GNN achieves state-of-the-art performance on Knowledge Graph Completion task and performs a better extrapolation ability. Our code is available at https://github.com/renli1024/SE-GNN.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Learning Generalizable Light Field Networks from Few Images

We explore a new strategy for few-shot novel view synthesis based on a neural light field representation. Given a target camera pose, an implicit neural network maps each ray to its target pixel's color directly. The network is conditioned on local ray features generated by coarse volumetric rendering from an explicit 3D feature volume. This volume is built from the input images using a 3D ConvNet. Our method achieves competitive performances on synthetic and real MVS data with respect to state-of-the-art neural radiance field based competition, while offering a 100 times faster rendering.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Machine Learning with DBOS

We recently proposed a new cluster operating system stack, DBOS, centered on a DBMS. DBOS enables unique support for ML applications by encapsulating ML code within stored procedures, centralizing ancillary ML data, providing security built into the underlying DBMS, co-locating ML code and data, and tracking data and workflow provenance. Here we demonstrate a subset of these benefits around two ML applications. We first show that image classification and object detection models using GPUs can be served as DBOS stored procedures with performance competitive to existing systems. We then present a 1D CNN trained to detect anomalies in HTTP requests on DBOS-backed web services, achieving SOTA results. We use this model to develop an interactive anomaly detection system and evaluate it through qualitative user feedback, demonstrating its usefulness as a proof of concept for future work to develop learned real-time security services on top of DBOS.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

New Distinguishers for Negation-Limited Weak Pseudorandom Functions

We show how to distinguish circuits with $\log k$ negations (a.k.a $k$-monotone functions) from uniformly random functions in $\exp\left(\tilde{O}\left(n^{1/3}k^{2/3}\right)\right)$ time using random samples. The previous best distinguisher, due to the learning algorithm by Blais, Cannone, Oliveira, Servedio, and Tan (RANDOM'15), requires $\exp\big(\tilde{O}(n^{1/2} k)\big)$ time. Our distinguishers are based on Fourier analysis on \emph{slices of the Boolean cube}. We show that some "middle" slices of negation-limited circuits have strong low-degree Fourier concentration and then we apply a variation of the classic Linial, Mansour, and Nisan "Low-Degree algorithm" (JACM'93) on slices. Our techniques also lead to a slightly improved weak learner for negation limited circuits under the uniform distribution.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Observation of SQUID-like behavior in fiber laser with intra-cavity epsilon-near-zero effect

Establishing relations between fundamental effects in far-flung areas of physics is a subject of great interest in the current research. We here report realization of a novel photonic system akin to the radio-frequency superconducting quantum interference device (RF-SQUID), in a fiber laser cavity with epsilon-near-zero (ENZ) nanolayers as intra-cavity components. Emulating the RF-SQUID scheme, the photonic counterpart of the supercurrent, represented by the optical wave, circulates in the cavity, passing through effective optical potential barriers. Different ENZ wavelengths translate into distinct spectral outputs through the variation of cavity resonances, emulating the situation with a frequency-varying tank circuit in the RF-SQUID. Due to the presence of the ENZ element, the optical potential barrier is far lower for selected frequency components, granting them advantage in the gain-resource competition. The findings reported in this work provide a deeper insight into the ultrafast ENZ photonics, revealing a new path towards the design of nanophotonic on-chip devices with various operational functions, and offer a new approach to study superconducting and quantum-mechanical systems.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Position-aware Structure Learning for Graph Topology-imbalance by Relieving Under-reaching and Over-squashing

Topology-imbalance is a graph-specific imbalance problem caused by the uneven topology positions of labeled nodes, which significantly damages the performance of GNNs. What topology-imbalance means and how to measure its impact on graph learning remain under-explored. In this paper, we provide a new understanding of topology-imbalance from a global view of the supervision information distribution in terms of under-reaching and over-squashing, which motivates two quantitative metrics as measurements. In light of our analysis, we propose a novel position-aware graph structure learning framework named PASTEL, which directly optimizes the information propagation path and solves the topology-imbalance issue in essence. Our key insight is to enhance the connectivity of nodes within the same class for more supervision information, thereby relieving the under-reaching and over-squashing phenomena. Specifically, we design an anchor-based position encoding mechanism, which better incorporates relative topology position and enhances the intra-class inductive bias by maximizing the label influence. We further propose a class-wise conflict measure as the edge weights, which benefits the separation of different node classes. Extensive experiments demonstrate the superior potential and adaptability of PASTEL in enhancing GNNs' power in different data annotation scenarios.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Reinforced Path Reasoning for Counterfactual Explainable Recommendation

Counterfactual explanations interpret the recommendation mechanism via exploring how minimal alterations on items or users affect the recommendation decisions. Existing counterfactual explainable approaches face huge search space and their explanations are either action-based (e.g., user click) or aspect-based (i.e., item description). We believe item attribute-based explanations are more intuitive and persuadable for users since they explain by fine-grained item demographic features (e.g., brand). Moreover, counterfactual explanation could enhance recommendations by filtering out negative items. In this work, we propose a novel Counterfactual Explainable Recommendation (CERec) to generate item attribute-based counterfactual explanations meanwhile to boost recommendation performance. Our CERec optimizes an explanation policy upon uniformly searching candidate counterfactuals within a reinforcement learning environment. We reduce the huge search space with an adaptive path sampler by using rich context information of a given knowledge graph. We also deploy the explanation policy to a recommendation model to enhance the recommendation. Extensive explainability and recommendation evaluations demonstrate CERec's ability to provide explanations consistent with user preferences and maintain improved recommendations. We release our code at https://github.com/Chrystalii/CERec.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Room-temperature printing of ultrathin Quasi-2D GaN semiconductor via liquid metal gallium surface confined nitridation reaction

Outstanding wide-bandgap semiconductor material such as gallium nitride (GaN) has been extensively utilized in power electronics, radiofrequency amplifiers, and harsh environment devices. Due to its quantum confinement effect in enabling desired deep-ultraviolet emission, excitonic impact, and electronic transport features, two-dimensional (2D) or ultrathin quasi-2D GaN semiconductors have been one of the most remarkable candidates for future growth of microelectronic devices. Here, for the first time, we reported a large area, wide bandgap, and room-temperature quasi-2D GaN synthesis and printing strategy through introducing the plasma medicated liquid metal gallium surface-confined nitridation reaction mechanism. The developed direct fabrication and compositional process is consistent with various electronics manufacturing approaches and thus opens an easy going way for cost-effective growth of the third-generation semiconductor. In particular, the fully printed field-effect transistors relying on the GaN thus made show p-type switching with an on/off ratio greater than 105, maximum field-effect hole mobility of 53 cm2/(V*s), and a small sub-threshold swing. As it was demonstrated, the present method allows to produce at room temperature the GaN with thickness spanning from 1nm to nanometers. This basic method can be further extended, generalized, and utilized for making various electronic and photoelectronic devices in the coming time.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Transactions Make Debugging Easy

We propose TROD, a novel transaction-oriented framework for debugging modern distributed web applications and online services. Our critical insight is that if applications store all state in databases and only access state transactionally, TROD can use lightweight always-on tracing to track the history of application state changes and data provenance, and then leverage the captured traces and transaction logs to faithfully replay or even test modified code retroactively on any past event. We demonstrate how TROD can simplify programming and debugging in production applications, list several research challenges and directions, and encourage the database and systems communities to drastically rethink the synergy between the way people develop and debug applications.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Universal Segmentation of 33 Anatomies

In the paper, we present an approach for learning a single model that universally segments 33 anatomical structures, including vertebrae, pelvic bones, and abdominal organs. Our model building has to address the following challenges. Firstly, while it is ideal to learn such a model from a large-scale, fully-annotated dataset, it is practically hard to curate such a dataset. Thus, we resort to learn from a union of multiple datasets, with each dataset containing the images that are partially labeled. Secondly, along the line of partial labelling, we contribute an open-source, large-scale vertebra segmentation dataset for the benefit of spine analysis community, CTSpine1K, boasting over 1,000 3D volumes and over 11K annotated vertebrae. Thirdly, in a 3D medical image segmentation task, due to the limitation of GPU memory, we always train a model using cropped patches as inputs instead a whole 3D volume, which limits the amount of contextual information to be learned. To this, we propose a cross-patch transformer module to fuse more information in adjacent patches, which enlarges the aggregated receptive field for improved segmentation performance. This is especially important for segmenting, say, the elongated spine. Based on 7 partially labeled datasets that collectively contain about 2,800 3D volumes, we successfully learn such a universal model. Finally, we evaluate the universal model on multiple open-source datasets, proving that our model has a good generalization performance and can potentially serve as a solid foundation for downstream tasks.

0 citations0 reviewsNo code linkedOpen access
preprint2021arXiv

Magnetic field-tuned quantum criticality in optimally electron-doped cuprate thin films

Antiferromagnetic (AF) spin fluctuations are commonly believed to play a key role in electron pairing of cuprate superconductors. In electron-doped cuprates, it is still in paradox about the interplay among different electronic states in quantum perturbations, especially between superconducting and magnetic states. Here, we report a systematic transport study on cation-optimized La2-xCexCuO4 (x = 0.10) thin films in high magnetic fields. We find an AF quantum phase transition near 60 T, where the Hall number jumps from nH =-x to nH = 1-x, resembling the change of nH at the AF boundary (xAF = 0.14) tuned by Ce doping. In the AF region a spin dependent state manifesting anomalous positive magnetoresistance is observed, which is closely related to superconductivity. Once the AF state is suppressed by magnetic field, a polarized ferromagnetic state is predicted, reminiscent of the recently reported ferromagnetic state at the quantum endpoint of the superconducting dome by Ce doping. The magnetic field that drives phase transitions in a similar but distinct manner to doping thereby provides a unique perspective to understand the quantum criticality of electron-doped cuprates.

0 citations0 reviewsNo code linkedOpen access
preprint2021arXiv

Population inversion and Dirac fermion cooling in 3D Dirac semimetal Cd$_3$As$_2$

Revealing the ultrafast dynamics of three-dimensional (3D) Dirac fermions upon photoexcitation is critical for both fundamental science and device applications. So far, how the cooling of 3D Dirac fermions differs from that of two-dimensional (2D) Dirac fermions and whether there is population inversion are fundamental questions that remain to be answered. Here we reveal the ultrafast dynamics of Dirac fermions in a model 3D Dirac semimetal Cd$_3$As$_2$ by ultrafast time- and angle-resolved photoemission spectroscopy (TrARPES) with a tunable probe photon energy from 5.3 - 6.9 eV. The energy- and momentum-resolved relaxation rate shows a linear dependence on the energy, suggesting Dirac fermion cooling through intraband relaxation. Moreover, a population inversion is reported based on the observation of accumulated photoexcited carriers in the conduction band with a lifetime of $τ_n$ = 3.0 ps. Our work provides direct experimental evidence for a long-lived population inversion in a 3D Dirac semimetal, which is in contrast to 2D graphene where the interband relaxation occurs on a much faster timescale.

0 citations0 reviewsNo code linkedOpen access
preprint2021arXiv

Room-temperature ferromagnetism at an oxide/nitride interface

Heterointerfaces have led to the discovery of novel electronic and magnetic states because of their strongly entangled electronic degrees of freedom. Single-phase chromium compounds always exhibit antiferromagnetism following the prediction of Goodenough-Kanamori rules. So far, exchange coupling between chromium ions via hetero-anions has not been explored and the associated quantum states is unknown. Here we report the successful epitaxial synthesis and characterizations of chromium oxide (Cr2O3)-chromium nitride (CrN) superlattices. Room-temperature ferromagnetic spin ordering is achieved at the interfaces between these two antiferromagnets, and the magnitude of the effect decays with increasing layer thickness. First-principles calculations indicate that robust ferromagnetic spin interaction between Cr3+ ions via anion-hybridizations across the interface yields the lowest total energy. This work opens the door to fundamental understanding of the unexpected and exceptional properties of oxide-nitride interfaces and provides access to hidden phases at low-dimensional quantum heterostructures.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Consistency of a kind of general noncanonical warm inflation

The framework of a kind of noncanonical warm inflation is introduced, and the dynamical equations of this scenario are presented. We propose the slow roll approximations and give some redefining slow roll parameters in this scenario which remain dimensionless. Performing systemic stability analysis, we calculate the slow roll conditions to guarantee that slow roll approximations hold. The slow roll conditions suggest slow roll inflation in general noncanonical warm inflationary scenario can still exist, and in addition, the slow roll approximations are more easily to be satisfied. Then, a concrete Dirac-Born-Infeld warm inflationary model is studied.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Embracing Imperfect Datasets: A Review of Deep Learning Solutions for Medical Image Segmentation

The medical imaging literature has witnessed remarkable progress in high-performing segmentation models based on convolutional neural networks. Despite the new performance highs, the recent advanced segmentation models still require large, representative, and high quality annotated datasets. However, rarely do we have a perfect training dataset, particularly in the field of medical imaging, where data and annotations are both expensive to acquire. Recently, a large body of research has studied the problem of medical image segmentation with imperfect datasets, tackling two major dataset limitations: scarce annotations where only limited annotated data is available for training, and weak annotations where the training data has only sparse annotations, noisy annotations, or image-level annotations. In this article, we provide a detailed review of the solutions above, summarizing both the technical novelties and empirical results. We further compare the benefits and requirements of the surveyed methodologies and provide our recommended solutions. We hope this survey article increases the community awareness of the techniques that are available to handle imperfect medical image segmentation datasets.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

How to Investigate the Historical Roots and Evolution of Research Fields in China? A Case Study on iMetrics Using RootCite

This paper aimed to provide an approach to investigate the historical roots and evolution of research fields in China by extending the reference publication year spectroscopy (RPYS). RootCite, an open source software accepts raw data from both the Web of Science and the China Social Science Citation Index (CSSCI), was developed using python. We took iMetrics in China as the research case. 5,141 Chinese iMetrics related publications with 73,376 non-distinct cited references (CR) collected from the CSSCI were analyzed using RootCite. The results showed that the first CR in the field can be dated back to 1882 and written in English; but the majority (64.2%) of the CR in the field were Chinese publications. 17 peaks referring to 18 seminal works (13 in English and 5 in Chinese) were located during the period from 1900 to 2017. The field shared the same roots with that in the English world but has its own characteristics, and it was then shaped by contributions from both the English world and China. The five Chinese works have played irreplaceable and positive roles in the historical evolutionary path of the field, which should not be ignored, especially for the evolution of the field. This research demonstrated how RootCite aided the task of identifying the origin and evolution of research fields in China, which could be valuable for extending RPYS for countries with other languages.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

INFaaS: A Model-less and Managed Inference Serving System

Despite existing work in machine learning inference serving, ease-of-use and cost efficiency remain challenges at large scales. Developers must manually search through thousands of model-variants -- versions of already-trained models that differ in hardware, resource footprints, latencies, costs, and accuracies -- to meet the diverse application requirements. Since requirements, query load, and applications themselves evolve over time, these decisions need to be made dynamically for each inference query to avoid excessive costs through naive autoscaling. To avoid navigating through the large and complex trade-off space of model-variants, developers often fix a variant across queries, and replicate it when load increases. However, given the diversity across variants and hardware platforms in the cloud, a lack of understanding of the trade-off space can incur significant costs to developers. This paper introduces INFaaS, a managed and model-less system for distributed inference serving, where developers simply specify the performance and accuracy requirements for their applications without needing to specify a specific model-variant for each query. INFaaS generates model-variants, and efficiently navigates the large trade-off space of model-variants on behalf of developers to meet application-specific objectives: (a) for each query, it selects a model, hardware architecture, and model optimizations, (b) it combines VM-level horizontal autoscaling with model-level autoscaling, where multiple, different model-variants are used to serve queries within each machine. By leveraging diverse variants and sharing hardware resources across models, INFaaS achieves 1.3x higher throughput, violates latency objectives 1.6x less often, and saves up to 21.6x in cost (8.5x on average) compared to state-of-the-art inference serving systems on AWS EC2.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Influence of Initialization on the Performance of Metaheuristic Optimizers

All metaheuristic optimization algorithms require some initialization, and the initialization for such optimizers is usually carried out randomly. However, initialization can have some significant influence on the performance of such algorithms. This paper presents a systematic comparison of 22 different initialization methods on the convergence and accuracy of five optimizers: differential evolution (DE), particle swarm optimization (PSO), cuckoo search (CS), artificial bee colony (ABC) algorithm and genetic algorithm (GA). We have used 19 different test functions with different properties and modalities to compare the possible effects of initialization, population sizes and the numbers of iterations. Rigorous statistical ranking tests indicate that 43.37\% of the functions using the DE algorithm show significant differences for different initialization methods, while 73.68\% of the functions using both PSO and CS algorithms are significantly affected by different initialization methods. The simulations show that DE is less sensitive to initialization, while both PSO and CS are more sensitive to initialization. In addition, under the condition of the same maximum number of function evaluations (FEs), the population size can also have a strong effect. Particle swarm optimization usually requires a larger population, while the cuckoo search needs only a small population size. Differential evolution depends more heavily on the number of iterations, a relatively small population with more iterations can lead to better results. Furthermore, ABC is more sensitive to initialization, while such initialization has little effect on GA. Some probability distributions such as the beta distribution, exponential distribution and Rayleigh distribution can usually lead to better performance. The implications of this study and further research topics are also discussed in detail.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Learning Differential Diagnosis of Skin Conditions with Co-occurrence Supervision using Graph Convolutional Networks

Skin conditions are reported the 4th leading cause of nonfatal disease burden worldwide. However, given the colossal spectrum of skin disorders defined clinically and shortage in dermatology expertise, diagnosing skin conditions in a timely and accurate manner remains a challenging task. Using computer vision technologies, a deep learning system has proven effective assisting clinicians in image diagnostics of radiology, ophthalmology and more. In this paper, we propose a deep learning system (DLS) that may predict differential diagnosis of skin conditions using clinical images. Our DLS formulates the differential diagnostics as a multi-label classification task over 80 conditions when only incomplete image labels are available. We tackle the label incompleteness problem by combining a classification network with a Graph Convolutional Network (GCN) that characterizes label co-occurrence and effectively regularizes it towards a sparse representation. Our approach is demonstrated on 136,462 clinical images and concludes that the classification accuracy greatly benefit from the Co-occurrence supervision. Our DLS achieves 93.6% top-5 accuracy on 12,378 test images and consistently outperform the baseline classification network.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Leveraging Multi-level Dependency of Relational Sequences for Social Spammer Detection

Much recent research has shed light on the development of the relation-dependent but content-independent framework for social spammer detection. This is largely because the relation among users is difficult to be altered when spammers attempt to conceal their malicious intents. Our study investigates the spammer detection problem in the context of multi-relation social networks, and makes an attempt to fully exploit the sequences of heterogeneous relations for enhancing the detection accuracy. Specifically, we present the Multi-level Dependency Model (MDM). The MDM is able to exploit user's long-term dependency hidden in their relational sequences along with short-term dependency. Moreover, MDM fully considers short-term relational sequences from the perspectives of individual-level and union-level, due to the fact that the type of short-term sequences is multi-folds. Experimental results on a real-world multi-relational social network demonstrate the effectiveness of our proposed MDM on multi-relational social spammer detection.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Neighborhood Information-based Probabilistic Algorithm for Network Disintegration

Many real-world applications can be modelled as complex networks, and such networks include the Internet, epidemic disease networks, transport networks, power grids, protein-folding structures and others. Network integrity and robustness are important to ensure that crucial networks are protected and undesired harmful networks can be dismantled. Network structure and integrity can be controlled by a set of key nodes, and to find the optimal combination of nodes in a network to ensure network structure and integrity can be an NP-complete problem. Despite extensive studies, existing methods have many limitations and there are still many unresolved problems. This paper presents a probabilistic approach based on neighborhood information and node importance, namely, neighborhood information-based probabilistic algorithm (NIPA). We also define a new centrality-based importance measure (IM), which combines the contribution ratios of the neighbor nodes of each target node and two-hop node information. Our proposed NIPA has been tested for different network benchmarks and compared with three other methods: optimal attack strategy (OAS), high betweenness first (HBF) and high degree first (HDF). Experiments suggest that the proposed NIPA is most effective among all four methods. In general, NIPA can identify the most crucial node combination with higher effectiveness, and the set of optimal key nodes found by our proposed NIPA is much smaller than that by heuristic centrality prediction. In addition, many previously neglected weakly connected nodes are identified, which become a crucial part of the newly identified optimal nodes. Thus, revised strategies for protection are recommended to ensure the safeguard of network integrity. Further key issues and future research topics are also discussed.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Region-Referenced Spectral Power Dynamics of EEG Signals: A Hierarchical Modeling Approach

Functional brain imaging through electroencephalography (EEG) relies upon the analysis and interpretation of high-dimensional, spatially organized time series. We propose to represent time-localized frequency domain characterizations of EEG data as region-referenced functional data. This representation is coupled with a hierarchical modeling approach to multivariate functional observations. Within this familiar setting, we discuss how several prior models relate to structural assumptions about multivariate covariance operators. An overarching modeling framework, based on infinite factorial decompositions, is finally proposed to balance flexibility and efficiency in estimation. The motivating application stems from a study of implicit auditory learning, in which typically developing (TD) children, and children with autism spectrum disorder (ASD) were exposed to a continuous speech stream. Using the proposed model, we examine differential band power dynamics as brain function is interrogated throughout the duration of a computer-controlled experiment. Our work offers a novel look at previous findings in psychiatry, and provides further insights into the understanding of ASD. Our approach to inference is fully Bayesian and implemented in a highly optimized Rcpp package.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Stochastic Batch Augmentation with An Effective Distilled Dynamic Soft Label Regularizer

Data augmentation have been intensively used in training deep neural network to improve the generalization, whether in original space (e.g., image space) or representation space. Although being successful, the connection between the synthesized data and the original data is largely ignored in training, without considering the distribution information that the synthesized samples are surrounding the original sample in training. Hence, the behavior of the network is not optimized for this. However, that behavior is crucially important for generalization, even in the adversarial setting, for the safety of the deep learning system. In this work, we propose a framework called Stochastic Batch Augmentation (SBA) to address these problems. SBA stochastically decides whether to augment at iterations controlled by the batch scheduler and in which a ''distilled'' dynamic soft label regularization is introduced by incorporating the similarity in the vicinity distribution respect to raw samples. The proposed regularization provides direct supervision by the KL-Divergence between the output soft-max distributions of original and virtual data. Our experiments on CIFAR-10, CIFAR-100, and ImageNet show that SBA can improve the generalization of the neural networks and speed up the convergence of network training.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Triaging moderate COVID-19 and other viral pneumonias from routine blood tests

The COVID-19 is sweeping the world with deadly consequences. Its contagious nature and clinical similarity to other pneumonias make separating subjects contracted with COVID-19 and non-COVID-19 viral pneumonia a priority and a challenge. However, COVID-19 testing has been greatly limited by the availability and cost of existing methods, even in developed countries like the US. Intrigued by the wide availability of routine blood tests, we propose to leverage them for COVID-19 testing using the power of machine learning. Two proven-robust machine learning model families, random forests (RFs) and support vector machines (SVMs), are employed to tackle the challenge. Trained on blood data from 208 moderate COVID-19 subjects and 86 subjects with non-COVID-19 moderate viral pneumonia, the best result is obtained in an SVM-based classifier with an accuracy of 84%, a sensitivity of 88%, a specificity of 80%, and a precision of 92%. The results are found explainable from both machine learning and medical perspectives. A privacy-protected web portal is set up to help medical personnel in their practice and the trained models are released for developers to further build other applications. We hope our results can help the world fight this pandemic and welcome clinical verification of our approach on larger populations.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Triple Memory Networks: a Brain-Inspired Method for Continual Learning

Continual acquisition of novel experience without interfering previously learned knowledge, i.e. continual learning, is critical for artificial neural networks, but limited by catastrophic forgetting. A neural network adjusts its parameters when learning a new task, but then fails to conduct the old tasks well. By contrast, the brain has a powerful ability to continually learn new experience without catastrophic interference. The underlying neural mechanisms possibly attribute to the interplay of hippocampus-dependent memory system and neocortex-dependent memory system, mediated by prefrontal cortex. Specifically, the two memory systems develop specialized mechanisms to consolidate information as more specific forms and more generalized forms, respectively, and complement the two forms of information in the interplay. Inspired by such brain strategy, we propose a novel approach named triple memory networks (TMNs) for continual learning. TMNs model the interplay of hippocampus, prefrontal cortex and sensory cortex (a neocortex region) as a triple-network architecture of generative adversarial networks (GAN). The input information is encoded as specific representation of the data distributions in a generator, or generalized knowledge of solving tasks in a discriminator and a classifier, with implementing appropriate brain-inspired algorithms to alleviate catastrophic forgetting in each module. Particularly, the generator replays generated data of the learned tasks to the discriminator and the classifier, both of which are implemented with a weight consolidation regularizer to complement the lost information in generation process. TMNs achieve new state-of-the-art performance on a variety of class-incremental learning benchmarks on MNIST, SVHN, CIFAR-10 and ImageNet-50, comparing with strong baseline methods.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

U-Net Using Stacked Dilated Convolutions for Medical Image Segmentation

This paper proposes a novel U-Net variant using stacked dilated convolutions for medical image segmentation (SDU-Net). SDU-Net adopts the architecture of vanilla U-Net with modifications in the encoder and decoder operations (an operation indicates all the processing for feature maps of the same resolution). Unlike vanilla U-Net which incorporates two standard convolutions in each encoder/decoder operation, SDU-Net uses one standard convolution followed by multiple dilated convolutions and concatenates all dilated convolution outputs as input to the next operation. Experiments showed that SDU-Net outperformed vanilla U-Net, attention U-Net (AttU-Net), and recurrent residual U-Net (R2U-Net) in all four tested segmentation tasks while using parameters around 40% of vanilla U-Net's, 17% of AttU-Net's, and 15% of R2U-Net's.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Weakly Supervised Context Encoder using DICOM metadata in Ultrasound Imaging

Modern deep learning algorithms geared towards clinical adaption rely on a significant amount of high fidelity labeled data. Low-resource settings pose challenges like acquiring high fidelity data and becomes the bottleneck for developing artificial intelligence applications. Ultrasound images, stored in Digital Imaging and Communication in Medicine (DICOM) format, have additional metadata data corresponding to ultrasound image parameters and medical exams. In this work, we leverage DICOM metadata from ultrasound images to help learn representations of the ultrasound image. We demonstrate that the proposed method outperforms the non-metadata based approaches across different downstream tasks.

0 citations0 reviewsNo code linkedOpen access
preprint2019arXiv

Coherent transfer of spin angular momentum by evanescent spin waves within antiferromagnetic NiO

Insulating antiferromagnets are efficient and robust conductors of spin current. To realise the full potential of these materials within spintronics, the outstanding challenges are to demonstrate scalability down to nanometric lengthscales and the transmission of coherent spin currents. Here, we report the coherent transfer of spin angular momentum by excitation of evanescent spin waves of GHz frequency within antiferromagnetic NiO at room temperature. Using element-specific and phase-resolved x-ray ferromagnetic resonance, we probe the injection and transmission of ac spin current, and demonstrate that insertion of a few nanometre thick epitaxial NiO(001) layer between a ferromagnet and non-magnet can even enhance the flow of spin current. Our results pave the way towards coherent control of the phase and amplitude of spin currents at the nanoscale, and enable the realization of spin-logic devices and spin current amplifiers that operate at GHz and THz frequencies.

0 citations0 reviewsNo code linkedOpen access
preprint2019arXiv

Emergent superconductivity in single crystalline $\mathrm{MgTi}_2\mathrm{O}_4$ films via structural engineering

Spinel compounds have demonstrated rich functionalities but rarely shown superconductivity. Here, we report the emergence of superconductivity in the spinel $\mathrm{MgTi}_2\mathrm{O}_4$, known to be an insulator with a complicated order. The superconducting transition is achieved by engineering a superlattice of $\mathrm{MgTi}_2\mathrm{O}_4$ and $\mathrm{SrTiO}_3$. The onset transition temperature in the $\mathrm{MgTi}_2\mathrm{O}_4$ layer can be tuned from 0 to 5 K in such geometry, concurrently with a stretched $c$-axis (from 8.51 to 8.53 Å) compared to the bulk material. Such a positive correlation without saturation suggests ample room for the further enhancement. Intriguingly, the superlattice exhibits isotropic upper critical field $H_{\mathrm{c}2}$ that breaks the Pauli limit, distinct from the highly anisotropic feature of interface superconductivity. The origin of superconductivity in the $\mathrm{MgTi}_2\mathrm{O}_4$ layer is understood in combination with the electron energy loss spectra and the first-principles electronic structure calculations, which point to the birth of superconductivity in the $\mathrm{MgTi}_2\mathrm{O}_4$ layer by preventing the Ti-Ti dimerization. Our discovery not only provides a platform to explore the interplay between the superconductivity and other exotic states, but also opens a new window to realize superconductivity in the spinel compounds as well as other titanium oxides.

0 citations0 reviewsNo code linkedOpen access
preprint2019arXiv

On some model equations for pulsatile flow in viscoelastic vessels

Considered here is the derivation of partial differential equations arising in pulsatile flow in pipes with viscoelastic walls. The equations are asymptotic models describing the propagation of long-crested pulses in pipes with cylindrical symmetry. Additional effects due to viscous stresses in bio-fluids are also taken into account. The effects of viscoelasticity of the vessels on the propagation of solitary and periodic waves in a vessel of constant radius are being explored numerically.

0 citations0 reviewsNo code linkedOpen access
preprint2018arXiv

A Reconfigurable Nanophotonics Platform for Sub-Millisecond, Deep Brain Neural Stimulation

Nanophotonics provides the ability to rapidly and precisely reconfigure light beams on a compact platform. Infrared nanophotonic devices are widely used in data communications to overcome traditional bandwidth limitations of electrical interconnects. Nanophotonic devices also hold promise for use in biological applications that require visible light, but this has remained technically elusive due to the challenges of reconfiguring and guiding light at these smaller dimensions. In neuroscience, for example, there is a need for implantable optical devices to optogenetically stimulate neurons across deep brain regions with the speed and precision matching state-of-the-art recording probes. Here we demonstrate the first platform for reconfigurable nanophotonic devices in the visible wavelength range and show its application in vivo in the brain. We demonstrate an implantable probe endowed with the ability to rapidly switch and route multiple optical beams using a nanoscale switching network. Each switch consists of a silicon nitride waveguide structure that can be reconfigured by electrically tuning the phase of light and is designed for robustness to fabrication variation, enabling scalable devices. By implanting our probe in mouse visual cortex, we demonstrate in vivo the ability to stimulate identified sets of neurons across layers to produce multi-neuron spike patterns and record them simultaneously with sub-millisecond temporal precision. This nanophotonic platform can be scaled up and integrated with high-density neural recording technologies, opening the door to implantable probe technologies that are able to simultaneously record and stimulate the activity of large neural populations at distant regions of the brain with sub-millisecond precision. We expect this platform will enable researchers to gain a deeper understanding into the spatio-temporal precision of the neural code.

0 citations0 reviewsNo code linkedOpen access
preprint2016arXiv

Soft Phonon Modes and Diffuse Scattering in Pb(In1/2Nb1/2)O3-Pb(Mg1/3Nb2/3)O3-PbTiO3 Relaxor Ferroelectrics

Single crystals of a ternary relaxor ferroelectric system, 0.29Pb(In1/2Nb1/2)O3-0.45Pb(Mg1/3Nb2/3)O3-0.26PbTiO3, have been studied using triple-axis based elastic and inelastic neutron scattering. Elastic diffuse scattering confirms the presence of polar nano-regions (PNRs) in this system. The PNRs emerge at the Burns temperature, TB = 630 K and then grow continuously in population and correlation size as the crystal cools down to 100 K. At 300 K, characteristic 'butterfly' and ellipsoid shaped diffuse scattering patterns are observed on the HK0 reciprocal space plane. Electrical poling along the [110] direction produces a marked asymmetry in the diffuse scattering patterns, with the parallel-to-the-field components enhanced while the perpendicular-to-the-field components suppressed. Several low energy phonon branches along the [001] and [111] directions were studied. Most significantly, the PNR-acoustic phonon coupling is confirmed for the [110] transverse acoustic (TA) phonons polarized along the [1-10] real space direction and the [100] TA phonons. This coupling appears to be anisotropic and correlated with the distribution of PNRs, and also affected by the relative length scales of the PNRs and phonon wave vectors. The well-known 'waterfall' phenomenon is observed on the [001] and [110] transverse optical (TO) branches, near the zone center. The optical phonon measurements also reveal a lowest-energy, zone center soft TO mode, whose squared phonon energy increase linearly with decreasing temperature below the TB.

0 citations0 reviewsNo code linkedOpen access