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Published work

36 published item(s)

preprint2026arXiv

Evidential Reasoning Advances Interpretable Real-World Disease Screening

Disease screening is critical for early detection and timely intervention in clinical practice. However, most current screening models for medical images suffer from limited interpretability and suboptimal performance. They often lack effective mechanisms to reference historical cases or provide transparent reasoning pathways. To address these challenges, we introduce EviScreen, an evidential reasoning framework for disease screening that leverages region-level evidence from historical cases. The proposed EviScreen offers retrospection interpretability through regional evidence retrieved from dual knowledge banks. Using this evidential mechanism, the subsequent evidence-aware reasoning module makes predictions using both the current case and evidence from historical cases, thereby enhancing disease screening performance. Furthermore, rather than relying on post-hoc saliency maps, EviScreen enhances localization interpretability by leveraging abnormality maps derived from contrastive retrieval. Our method achieves superior performance on our carefully established benchmarks for real-world disease screening, yielding notably higher specificity at clinical-level recall. Code is publicly available at https://github.com/DopamineLcy/EviScreen.

preprint2023arXiv

AGConv: Adaptive Graph Convolution on 3D Point Clouds

Convolution on 3D point clouds is widely researched yet far from perfect in geometric deep learning. The traditional wisdom of convolution characterises feature correspondences indistinguishably among 3D points, arising an intrinsic limitation of poor distinctive feature learning. In this paper, we propose Adaptive Graph Convolution (AGConv) for wide applications of point cloud analysis. AGConv generates adaptive kernels for points according to their dynamically learned features. Compared with the solution of using fixed/isotropic kernels, AGConv improves the flexibility of point cloud convolutions, effectively and precisely capturing the diverse relations between points from different semantic parts. Unlike the popular attentional weight schemes, AGConv implements the adaptiveness inside the convolution operation instead of simply assigning different weights to the neighboring points. Extensive evaluations clearly show that our method outperforms state-of-the-arts of point cloud classification and segmentation on various benchmark datasets.Meanwhile, AGConv can flexibly serve more point cloud analysis approaches to boost their performance. To validate its flexibility and effectiveness, we explore AGConv-based paradigms of completion, denoising, upsampling, registration and circle extraction, which are comparable or even superior to their competitors. Our code is available at https://github.com/hrzhou2/AdaptConv-master.

preprint2022arXiv

A New Dataset and A Baseline Model for Breast Lesion Detection in Ultrasound Videos

Breast lesion detection in ultrasound is critical for breast cancer diagnosis. Existing methods mainly rely on individual 2D ultrasound images or combine unlabeled video and labeled 2D images to train models for breast lesion detection. In this paper, we first collect and annotate an ultrasound video dataset (188 videos) for breast lesion detection. Moreover, we propose a clip-level and video-level feature aggregated network (CVA-Net) for addressing breast lesion detection in ultrasound videos by aggregating video-level lesion classification features and clip-level temporal features. The clip-level temporal features encode local temporal information of ordered video frames and global temporal information of shuffled video frames. In our CVA-Net, an inter-video fusion module is devised to fuse local features from original video frames and global features from shuffled video frames, and an intra-video fusion module is devised to learn the temporal information among adjacent video frames. Moreover, we learn video-level features to classify the breast lesions of the original video as benign or malignant lesions to further enhance the final breast lesion detection performance in ultrasound videos. Experimental results on our annotated dataset demonstrate that our CVA-Net clearly outperforms state-of-the-art methods. The corresponding code and dataset are publicly available at \url{https://github.com/jhl-Det/CVA-Net}.

preprint2022arXiv

An Improved Normed-Deformable Convolution for Crowd Counting

In recent years, crowd counting has become an important issue in computer vision. In most methods, the density maps are generated by convolving with a Gaussian kernel from the ground-truth dot maps which are marked around the center of human heads. Due to the fixed geometric structures in CNNs and indistinct head-scale information, the head features are obtained incompletely. Deformable convolution is proposed to exploit the scale-adaptive capabilities for CNN features in the heads. By learning the coordinate offsets of the sampling points, it is tractable to improve the ability to adjust the receptive field. However, the heads are not uniformly covered by the sampling points in the deformable convolution, resulting in loss of head information. To handle the non-uniformed sampling, an improved Normed-Deformable Convolution (\textit{i.e.,}NDConv) implemented by Normed-Deformable loss (\textit{i.e.,}NDloss) is proposed in this paper. The offsets of the sampling points which are constrained by NDloss tend to be more even. Then, the features in the heads are obtained more completely, leading to better performance. Especially, the proposed NDConv is a light-weight module which shares similar computation burden with Deformable Convolution. In the extensive experiments, our method outperforms state-of-the-art methods on ShanghaiTech A, ShanghaiTech B, UCF\_QNRF, and UCF\_CC\_50 dataset, achieving 61.4, 7.8, 91.2, and 167.2 MAE, respectively. The code is available at https://github.com/bingshuangzhuzi/NDConv

preprint2022arXiv

CSDN: Cross-modal Shape-transfer Dual-refinement Network for Point Cloud Completion

How will you repair a physical object with some missings? You may imagine its original shape from previously captured images, recover its overall (global) but coarse shape first, and then refine its local details. We are motivated to imitate the physical repair procedure to address point cloud completion. To this end, we propose a cross-modal shape-transfer dual-refinement network (termed CSDN), a coarse-to-fine paradigm with images of full-cycle participation, for quality point cloud completion. CSDN mainly consists of "shape fusion" and "dual-refinement" modules to tackle the cross-modal challenge. The first module transfers the intrinsic shape characteristics from single images to guide the geometry generation of the missing regions of point clouds, in which we propose IPAdaIN to embed the global features of both the image and the partial point cloud into completion. The second module refines the coarse output by adjusting the positions of the generated points, where the local refinement unit exploits the geometric relation between the novel and the input points by graph convolution, and the global constraint unit utilizes the input image to fine-tune the generated offset. Different from most existing approaches, CSDN not only explores the complementary information from images but also effectively exploits cross-modal data in the whole coarse-to-fine completion procedure. Experimental results indicate that CSDN performs favorably against ten competitors on the cross-modal benchmark.

preprint2022arXiv

Dynamic Message Propagation Network for RGB-D Salient Object Detection

This paper presents a novel deep neural network framework for RGB-D salient object detection by controlling the message passing between the RGB images and depth maps on the feature level and exploring the long-range semantic contexts and geometric information on both RGB and depth features to infer salient objects. To achieve this, we formulate a dynamic message propagation (DMP) module with the graph neural networks and deformable convolutions to dynamically learn the context information and to automatically predict filter weights and affinity matrices for message propagation control. We further embed this module into a Siamese-based network to process the RGB image and depth map respectively and design a multi-level feature fusion (MFF) module to explore the cross-level information between the refined RGB and depth features. Compared with 17 state-of-the-art methods on six benchmark datasets for RGB-D salient object detection, experimental results show that our method outperforms all the others, both quantitatively and visually.

preprint2022arXiv

Editing Out-of-domain GAN Inversion via Differential Activations

Despite the demonstrated editing capacity in the latent space of a pretrained GAN model, inverting real-world images is stuck in a dilemma that the reconstruction cannot be faithful to the original input. The main reason for this is that the distributions between training and real-world data are misaligned, and because of that, it is unstable of GAN inversion for real image editing. In this paper, we propose a novel GAN prior based editing framework to tackle the out-of-domain inversion problem with a composition-decomposition paradigm. In particular, during the phase of composition, we introduce a differential activation module for detecting semantic changes from a global perspective, \ie, the relative gap between the features of edited and unedited images. With the aid of the generated Diff-CAM mask, a coarse reconstruction can intuitively be composited by the paired original and edited images. In this way, the attribute-irrelevant regions can be survived in almost whole, while the quality of such an intermediate result is still limited by an unavoidable ghosting effect. Consequently, in the decomposition phase, we further present a GAN prior based deghosting network for separating the final fine edited image from the coarse reconstruction. Extensive experiments exhibit superiorities over the state-of-the-art methods, in terms of qualitative and quantitative evaluations. The robustness and flexibility of our method is also validated on both scenarios of single attribute and multi-attribute manipulations.

preprint2022arXiv

Hand Gesture Recognition Based on a Nonconvex Regularization

Recognition of hand gestures is one of the most fundamental tasks in human-robot interaction. Sparse representation based methods have been widely used due to their efficiency and low demands on the training data. Recently, nonconvex regularization techniques including the $\ell_{1-2}$ regularization have been proposed in the image processing community to promote sparsity while achieving efficient performance. In this paper, we propose a vision-based hand gesture recognition model based on the $\ell_{1-2}$ regularization, which is solved by the alternating direction method of multipliers (ADMM). Numerical experiments on binary and gray-scale data sets have demonstrated the effectiveness of this method in identifying hand gestures.

preprint2022arXiv

Nearly optimal capture-recapture sampling and empirical likelihood weighting estimation for M-estimation with big data

Subsampling techniques can reduce the computational costs of processing big data. Practical subsampling plans typically involve initial uniform sampling and refined sampling. With a subsample, big data inferences are generally built on the inverse probability weighting (IPW), which becomes unstable when the probability weights are close to zero and cannot incorporate auxiliary information. First, we consider capture-recapture sampling, which combines an initial uniform sampling with a second Poisson sampling. Under this sampling plan, we propose an empirical likelihood weighting (ELW) estimation approach to an M-estimation parameter. Second, based on the ELW method, we construct a nearly optimal capture-recapture sampling plan that balances estimation efficiency and computational costs. Third, we derive methods for determining the smallest sample sizes with which the proposed sampling-and-estimation method produces estimators of guaranteed precision. Our ELW method overcomes the instability of IPW by circumventing the use of inverse probabilities, and utilizes auxiliary information including the size and certain sample moments of big data. We show that the proposed ELW method produces more efficient estimators than IPW, leading to more efficient optimal sampling plans and more economical sample sizes for a prespecified estimation precision. These advantages are confirmed through simulation studies and real data analyses.

preprint2022arXiv

Refine-Net: Normal Refinement Neural Network for Noisy Point Clouds

Point normal, as an intrinsic geometric property of 3D objects, not only serves conventional geometric tasks such as surface consolidation and reconstruction, but also facilitates cutting-edge learning-based techniques for shape analysis and generation. In this paper, we propose a normal refinement network, called Refine-Net, to predict accurate normals for noisy point clouds. Traditional normal estimation wisdom heavily depends on priors such as surface shapes or noise distributions, while learning-based solutions settle for single types of hand-crafted features. Differently, our network is designed to refine the initial normal of each point by extracting additional information from multiple feature representations. To this end, several feature modules are developed and incorporated into Refine-Net by a novel connection module. Besides the overall network architecture of Refine-Net, we propose a new multi-scale fitting patch selection scheme for the initial normal estimation, by absorbing geometry domain knowledge. Also, Refine-Net is a generic normal estimation framework: 1) point normals obtained from other methods can be further refined, and 2) any feature module related to the surface geometric structures can be potentially integrated into the framework. Qualitative and quantitative evaluations demonstrate the clear superiority of Refine-Net over the state-of-the-arts on both synthetic and real-scanned datasets. Our code is available at https://github.com/hrzhou2/refinenet.

preprint2022arXiv

Relational Graph Neural Network Design via Progressive Neural Architecture Search

We propose a novel solution to addressing a long-standing dilemma in the representation learning of graph neural networks (GNNs): how to effectively capture and represent useful information embedded in long-distance nodes to improve the performance of nodes with low homophily without leading to performance degradation in nodes with high homophily. This dilemma limits the generalization capability of existing GNNs. Intuitively, interactions with distant nodes introduce more noise for a node than those with close neighbors. However, in most existing works, messages being passed among nodes are mingled together, which is inefficient from a communication perspective. Our solution is based on a novel, simple, yet effective aggregation scheme, resulting in a ladder-style GNN architecture, namely LADDER-GNN. Specifically, we separate messages from different hops, assign different dimensions for them, and then concatenate them to obtain node representations. Such disentangled representations facilitate improving the information-to-noise ratio of messages passed from different hops. To explore an effective hop-dimension relationship, we develop a conditionally progressive neural architecture search strategy. Based on the searching results, we further propose an efficient approximate hop-dimension relation function to facilitate the rapid configuration of the proposed LADDER-GNN. We verify the proposed LADDER-GNN on seven diverse semi-supervised node classification datasets. Experimental results show that our solution achieves better performance than most existing GNNs. We further analyze our aggregation scheme with two commonly used GNN architectures, and the results corroborate that our scheme outperforms existing schemes in classifying low homophily nodes by a large margin.

preprint2022arXiv

Robust Dual-Graph Regularized Moving Object Detection

Moving object detection and its associated background-foreground separation have been widely used in a lot of applications, including computer vision, transportation and surveillance. Due to the presence of the static background, a video can be naturally decomposed into a low-rank background and a sparse foreground. Many regularization techniques, such as matrix nuclear norm, have been imposed on the background. In the meanwhile, sparsity or smoothness based regularizations, such as total variation and $\ell_1$, can be imposed on the foreground. Moreover, graph Laplacians are further imposed to capture the complicated geometry of background images. Recently, weighted regularization techniques including the weighted nuclear norm regularization have been proposed in the image processing community to promote adaptive sparsity while achieving efficient performance. In this paper, we propose a robust dual-graph regularized moving object detection model based on the weighted nuclear norm regularization, which is solved by the alternating direction method of multipliers (ADMM). Numerical experiments on body movement data sets have demonstrated the effectiveness of this method in separating moving objects from background, and the great potential in robotic applications.

preprint2022arXiv

Separated Contrastive Learning for Organ-at-Risk and Gross-Tumor-Volume Segmentation with Limited Annotation

Automatic delineation of organ-at-risk (OAR) and gross-tumor-volume (GTV) is of great significance for radiotherapy planning. However, it is a challenging task to learn powerful representations for accurate delineation under limited pixel (voxel)-wise annotations. Contrastive learning at pixel-level can alleviate the dependency on annotations by learning dense representations from unlabeled data. Recent studies in this direction design various contrastive losses on the feature maps, to yield discriminative features for each pixel in the map. However, pixels in the same map inevitably share semantics to be closer than they actually are, which may affect the discrimination of pixels in the same map and lead to the unfair comparison to pixels in other maps. To address these issues, we propose a separated region-level contrastive learning scheme, namely SepaReg, the core of which is to separate each image into regions and encode each region separately. Specifically, SepaReg comprises two components: a structure-aware image separation (SIS) module and an intra- and inter-organ distillation (IID) module. The SIS is proposed to operate on the image set to rebuild a region set under the guidance of structural information. The inter-organ representation will be learned from this set via typical contrastive losses cross regions. On the other hand, the IID is proposed to tackle the quantity imbalance in the region set as tiny organs may produce fewer regions, by exploiting intra-organ representations. We conducted extensive experiments to evaluate the proposed model on a public dataset and two private datasets. The experimental results demonstrate the effectiveness of the proposed model, consistently achieving better performance than state-of-the-art approaches. Code is available at https://github.com/jcwang123/Separate_CL.

preprint2022arXiv

Test-time Adaptation with Calibration of Medical Image Classification Nets for Label Distribution Shift

Class distribution plays an important role in learning deep classifiers. When the proportion of each class in the test set differs from the training set, the performance of classification nets usually degrades. Such a label distribution shift problem is common in medical diagnosis since the prevalence of disease vary over location and time. In this paper, we propose the first method to tackle label shift for medical image classification, which effectively adapt the model learned from a single training label distribution to arbitrary unknown test label distribution. Our approach innovates distribution calibration to learn multiple representative classifiers, which are capable of handling different one-dominating-class distributions. When given a test image, the diverse classifiers are dynamically aggregated via the consistency-driven test-time adaptation, to deal with the unknown test label distribution. We validate our method on two important medical image classification tasks including liver fibrosis staging and COVID-19 severity prediction. Our experiments clearly show the decreased model performance under label shift. With our method, model performance significantly improves on all the test datasets with different label shifts for both medical image diagnosis tasks.

preprint2022arXiv

Transformer-empowered Multi-scale Contextual Matching and Aggregation for Multi-contrast MRI Super-resolution

Magnetic resonance imaging (MRI) can present multi-contrast images of the same anatomical structures, enabling multi-contrast super-resolution (SR) techniques. Compared with SR reconstruction using a single-contrast, multi-contrast SR reconstruction is promising to yield SR images with higher quality by leveraging diverse yet complementary information embedded in different imaging modalities. However, existing methods still have two shortcomings: (1) they neglect that the multi-contrast features at different scales contain different anatomical details and hence lack effective mechanisms to match and fuse these features for better reconstruction; and (2) they are still deficient in capturing long-range dependencies, which are essential for the regions with complicated anatomical structures. We propose a novel network to comprehensively address these problems by developing a set of innovative Transformer-empowered multi-scale contextual matching and aggregation techniques; we call it McMRSR. Firstly, we tame transformers to model long-range dependencies in both reference and target images. Then, a new multi-scale contextual matching method is proposed to capture corresponding contexts from reference features at different scales. Furthermore, we introduce a multi-scale aggregation mechanism to gradually and interactively aggregate multi-scale matched features for reconstructing the target SR MR image. Extensive experiments demonstrate that our network outperforms state-of-the-art approaches and has great potential to be applied in clinical practice. Codes are available at https://github.com/XAIMI-Lab/McMRSR.

preprint2022arXiv

Tuning-parameter-free optimal propensity score matching approach for causal inference

Propensity score matching (PSM) is a pseudo-experimental method that uses statistical techniques to construct an artificial control group by matching each treated unit with one or more untreated units of similar characteristics. To date, the problem of determining the optimal number of matches per unit, which plays an important role in PSM, has not been adequately addressed. We propose a tuning-parameter-free PSM method based on the nonparametric maximum-likelihood estimation of the propensity score under the monotonicity constraint. The estimated propensity score is piecewise constant, and therefore automatically groups data. Hence, our proposal is free of tuning parameters. The proposed estimator is asymptotically semiparametric efficient for the univariate case, and achieves this level of efficiency in the multivariate case when the outcome and the propensity score depend on the covariate in the same direction. We conclude that matching methods based on the propensity score alone cannot, in general, be efficient.

preprint2022arXiv

UCL-Dehaze: Towards Real-world Image Dehazing via Unsupervised Contrastive Learning

While the wisdom of training an image dehazing model on synthetic hazy data can alleviate the difficulty of collecting real-world hazy/clean image pairs, it brings the well-known domain shift problem. From a different yet new perspective, this paper explores contrastive learning with an adversarial training effort to leverage unpaired real-world hazy and clean images, thus bridging the gap between synthetic and real-world haze is avoided. We propose an effective unsupervised contrastive learning paradigm for image dehazing, dubbed UCL-Dehaze. Unpaired real-world clean and hazy images are easily captured, and will serve as the important positive and negative samples respectively when training our UCL-Dehaze network. To train the network more effectively, we formulate a new self-contrastive perceptual loss function, which encourages the restored images to approach the positive samples and keep away from the negative samples in the embedding space. Besides the overall network architecture of UCL-Dehaze, adversarial training is utilized to align the distributions between the positive samples and the dehazed images. Compared with recent image dehazing works, UCL-Dehaze does not require paired data during training and utilizes unpaired positive/negative data to better enhance the dehazing performance. We conduct comprehensive experiments to evaluate our UCL-Dehaze and demonstrate its superiority over the state-of-the-arts, even only 1,800 unpaired real-world images are used to train our network. Source code has been available at https://github.com/yz-wang/UCL-Dehaze.

preprint2022arXiv

UTOPIC: Uncertainty-aware Overlap Prediction Network for Partial Point Cloud Registration

High-confidence overlap prediction and accurate correspondences are critical for cutting-edge models to align paired point clouds in a partial-to-partial manner. However, there inherently exists uncertainty between the overlapping and non-overlapping regions, which has always been neglected and significantly affects the registration performance. Beyond the current wisdom, we propose a novel uncertainty-aware overlap prediction network, dubbed UTOPIC, to tackle the ambiguous overlap prediction problem; to our knowledge, this is the first to explicitly introduce overlap uncertainty to point cloud registration. Moreover, we induce the feature extractor to implicitly perceive the shape knowledge through a completion decoder, and present a geometric relation embedding for Transformer to obtain transformation-invariant geometry-aware feature representations. With the merits of more reliable overlap scores and more precise dense correspondences, UTOPIC can achieve stable and accurate registration results, even for the inputs with limited overlapping areas. Extensive quantitative and qualitative experiments on synthetic and real benchmarks demonstrate the superiority of our approach over state-of-the-art methods.

preprint2022arXiv

XBound-Former: Toward Cross-scale Boundary Modeling in Transformers

Skin lesion segmentation from dermoscopy images is of great significance in the quantitative analysis of skin cancers, which is yet challenging even for dermatologists due to the inherent issues, i.e., considerable size, shape and color variation, and ambiguous boundaries. Recent vision transformers have shown promising performance in handling the variation through global context modeling. Still, they have not thoroughly solved the problem of ambiguous boundaries as they ignore the complementary usage of the boundary knowledge and global contexts. In this paper, we propose a novel cross-scale boundary-aware transformer, \textbf{XBound-Former}, to simultaneously address the variation and boundary problems of skin lesion segmentation. XBound-Former is a purely attention-based network and catches boundary knowledge via three specially designed learners. We evaluate the model on two skin lesion datasets, ISIC-2016\&PH$^2$ and ISIC-2018, where our model consistently outperforms other convolution- and transformer-based models, especially on the boundary-wise metrics. We extensively verify the generalization ability of polyp lesion segmentation that has similar characteristics, and our model can also yield significant improvement compared to the latest models.

preprint2021arXiv

Regularized Kaczmarz Algorithms for Tensor Recovery

Tensor recovery has recently arisen in a lot of application fields, such as transportation, medical imaging and remote sensing. Under the assumption that signals possess sparse and/or low-rank structures, many tensor recovery methods have been developed to apply various regularization techniques together with the operator-splitting type of algorithms. Due to the unprecedented growth of data, it becomes increasingly desirable to use streamlined algorithms to achieve real-time computation, such as stochastic optimization algorithms that have recently emerged as an efficient family of methods in machine learning. In this work, we propose a novel algorithmic framework based on the Kaczmarz algorithm for tensor recovery. We provide thorough convergence analysis and its applications from the vector case to the tensor one. Numerical results on a variety of tensor recovery applications, including sparse signal recovery, low-rank tensor recovery, image inpainting and deconvolution, illustrate the enormous potential of the proposed methods.

preprint2021arXiv

Research Progress of News Recommendation Methods

Due to researchers'aim to study personalized recommendations for different business fields, the summary of recommendation methods in specific fields is of practical significance. News recommendation systems were the earliest research field regarding recommendation systems, and were also the earliest recommendation field to apply the collaborative filtering method. In addition, news is real-time and rich in content, which makes news recommendation methods more challenging than in other fields. Thus, this paper summarizes the research progress regarding news recommendation methods. From 2018 to 2020, developed news recommendation methods were mainly deep learning-based, attention-based, and knowledge graphs-based. As of 2020, there are many news recommendation methods that combine attention mechanisms and knowledge graphs. However, these methods were all developed based on basic methods (the collaborative filtering method, the content-based recommendation method, and a mixed recommendation method combining the two). In order to allow researchers to have a detailed understanding of the development process of news recommendation methods, the news recommendation methods surveyed in this paper, which cover nearly 10 years, are divided into three categories according to the abovementioned basic methods. Firstly, the paper introduces the basic ideas of each category of methods and then summarizes the recommendation methods that are combined with other methods based on each category of methods and according to the time sequence of research results. Finally, this paper also summarizes the challenges confronting news recommendation systems.

preprint2021arXiv

Two-stage Geometric Information Guided Image Reconstruction

In compressive sensing, it is challenging to reconstruct image of high quality from very few noisy linear projections. Existing methods mostly work well on piecewise constant images but not so well on piecewise smooth images such as natural images, medical images that contain a lot of details. We propose a two-stage method called GeoCS to recover images with rich geometric information from very limited amount of noisy measurements. The method adopts the shearlet transform that is mathematically proven to be optimal in sparsely representing images containing anisotropic features such as edges, corners, spikes etc. It also uses the weighted total variation (TV) sparsity with spatially variant weights to preserve sharp edges but to reduce the staircase effects of TV. Geometric information extracted from the results of stage I serves as an initial prior for stage II which alternates image reconstruction and geometric information update in a mutually beneficial way. GeoCS has been tested on incomplete spectral Fourier samples. It is applicable to other types of measurements as well. Experimental results on various complicated images show that GeoCS is efficient and generates high-quality images.

preprint2020arXiv

A Nonparametric Likelihood Approach for Inference in Instrumental Variable Models

Instrumental variable methods allow for inference about the treatment effect by controlling for unmeasured confounding in randomized experiments with noncompliance. However, many studies do not consider the observed compliance behavior in the testing procedure, which can lead to a loss of power. In this paper, we propose a novel nonparametric likelihood approach, referred to as the binomial likelihood (BL) method, that incorporates information on compliance behavior while overcoming several limitations of previous techniques and utilizing the advantages of likelihood methods. Our proposed method produces proper estimates of the counterfactual distribution functions by maximizing the binomial likelihood over the space of distribution functions. Using this we propose two versions of a binomial likelihood ratio test for the null hypothesis of no treatment effect. We show that both versions are more powerful to detect any distributional change than existing methods in finite sample cases, and are asymptotically equivalent to the two-sample Anderson-Darling test. We also develop an efficient algorithm for computing our estimates, and apply the binomial likelihood method to a study of the effect of Medicaid coverage on mental health using the Oregon Health Insurance Experiment.

preprint2020arXiv

A Novel Regularization Based on the Error Function for Sparse Recovery

Regularization plays an important role in solving ill-posed problems by adding extra information about the desired solution, such as sparsity. Many regularization terms usually involve some vector norm, e.g., $L_1$ and $L_2$ norms. In this paper, we propose a novel regularization framework that uses the error function to approximate the unit step function. It can be considered as a surrogate function for the $L_0$ norm. The asymptotic behavior of the error function with respect to its intrinsic parameter indicates that the proposed regularization can approximate the standard $L_0$, $L_1$ norms as the parameter approaches to $0$ and $\infty,$ respectively. Statistically, it is also less biased than the $L_1$ approach. We then incorporate the error function into either a constrained or an unconstrained model when recovering a sparse signal from an under-determined linear system. Computationally, both problems can be solved via an iterative reweighted $L_1$ (IRL1) algorithm with guaranteed convergence. A large number of experimental results demonstrate that the proposed approach outperforms the state-of-the-art methods in various sparse recovery scenarios.

preprint2020arXiv

A selective review on calibration information from similar studies based on parametric likelihood or empirical likelihood

In multi-center clinical trials, due to various reasons, the individual-level data are strictly restricted to be assessed publicly. Instead, the summarized information is widely available from published results. With the advance of computational technology, it has become very common in data analyses to run on hundreds or thousands of machines simultaneous, with the data distributed across those machines and no longer available in a single central location. How to effectively assemble the summarized clinical data information or information from each machine in parallel computation has become a challenging task for statisticians and computer scientists. In this paper, we selectively review some recently-developed statistical methods, including communication efficient distributed statistical inference, and renewal estimation and incremental inference, which can be regarded as the latest development of calibration information methods in the era of big data. Even though those methods were developed in different fields and in different statistical frameworks, in principle, they are asymptotically equivalent to those well known methods developed in meta analysis. Almost no or little information is lost compared with the case when full data are available. As a general tool to integrate information, we also review the generalized method of moments and estimating equations approach by using empirical likelihood method.

preprint2020arXiv

CNN in CT Image Segmentation: Beyound Loss Function for Expoliting Ground Truth Images

Exploiting more information from ground truth (GT) images now is a new research direction for further improving CNN's performance in CT image segmentation. Previous methods focus on devising the loss function for fulfilling such a purpose. However, it is rather difficult to devise a general and optimization-friendly loss function. We here present a novel and practical method that exploits GT images beyond the loss function. Our insight is that feature maps of two CNNs trained respectively on GT and CT images should be similar on some metric space, because they both are used to describe the same objects for the same purpose. We hence exploit GT images by enforcing such two CNNs' feature maps to be consistent. We assess the proposed method on two data sets, and compare its performance to several competitive methods. Extensive experimental results show that the proposed method is effective, outperforming all the compared methods.

preprint2020arXiv

Constrained Multi-shape Evolution for Overlapping Cytoplasm Segmentation

Segmenting overlapping cytoplasm of cells in cervical smear images is a clinically essential task, for quantitatively measuring cell-level features in order to diagnose cervical cancer. This task, however, remains rather challenging, mainly due to the deficiency of intensity (or color) information in the overlapping region. Although shape prior-based models that compensate intensity deficiency by introducing prior shape information (shape priors) about cytoplasm are firmly established, they often yield visually implausible results, mainly because they model shape priors only by limited shape hypotheses about cytoplasm, exploit cytoplasm-level shape priors alone, and impose no shape constraint on the resulting shape of the cytoplasm. In this paper, we present a novel and effective shape prior-based approach, called constrained multi-shape evolution, that segments all overlapping cytoplasms in the clump simultaneously by jointly evolving each cytoplasm's shape guided by the modeled shape priors. We model local shape priors (cytoplasm--level) by an infinitely large shape hypothesis set which contains all possible shapes of the cytoplasm. In the shape evolution, we compensate intensity deficiency for the segmentation by introducing not only the modeled local shape priors but also global shape priors (clump--level) modeled by considering mutual shape constraints of cytoplasms in the clump. We also constrain the resulting shape in each evolution to be in the built shape hypothesis set, for further reducing implausible segmentation results. We evaluated the proposed method in two typical cervical smear datasets, and the extensive experimental results show that the proposed method is effective to segment overlapping cytoplasm, consistently outperforming the state-of-the-art methods.

preprint2020arXiv

MBA-RainGAN: Multi-branch Attention Generative Adversarial Network for Mixture of Rain Removal from Single Images

Rain severely hampers the visibility of scene objects when images are captured through glass in heavily rainy days. We observe three intriguing phenomenons that, 1) rain is a mixture of raindrops, rain streaks and rainy haze; 2) the depth from the camera determines the degrees of object visibility, where objects nearby and faraway are visually blocked by rain streaks and rainy haze, respectively; and 3) raindrops on the glass randomly affect the object visibility of the whole image space. We for the first time consider that, the overall visibility of objects is determined by the mixture of rain (MOR). However, existing solutions and established datasets lack full consideration of the MOR. In this work, we first formulate a new rain imaging model; by then, we enrich the popular RainCityscapes by considering raindrops, named RainCityscapes++. Furthermore, we propose a multi-branch attention generative adversarial network (termed an MBA-RainGAN) to fully remove the MOR. The experiment shows clear visual and numerical improvements of our approach over the state-of-the-arts on RainCityscapes++. The code and dataset will be available.

preprint2020arXiv

Robust Multimodal Brain Tumor Segmentation via Feature Disentanglement and Gated Fusion

Accurate medical image segmentation commonly requires effective learning of the complementary information from multimodal data. However, in clinical practice, we often encounter the problem of missing imaging modalities. We tackle this challenge and propose a novel multimodal segmentation framework which is robust to the absence of imaging modalities. Our network uses feature disentanglement to decompose the input modalities into the modality-specific appearance code, which uniquely sticks to each modality, and the modality-invariant content code, which absorbs multimodal information for the segmentation task. With enhanced modality-invariance, the disentangled content code from each modality is fused into a shared representation which gains robustness to missing data. The fusion is achieved via a learning-based strategy to gate the contribution of different modalities at different locations. We validate our method on the important yet challenging multimodal brain tumor segmentation task with the BRATS challenge dataset. With competitive performance to the state-of-the-art approaches for full modality, our method achieves outstanding robustness under various missing modality(ies) situations, significantly exceeding the state-of-the-art method by over 16% in average for Dice on whole tumor segmentation.

preprint2020arXiv

Stochastic Greedy Algorithms For Multiple Measurement Vectors

Sparse representation of a single measurement vector (SMV) has been explored in a variety of compressive sensing applications. Recently, SMV models have been extended to solve multiple measurement vectors (MMV) problems, where the underlying signal is assumed to have joint sparse structures. To circumvent the NP-hardness of the $\ell_0$ minimization problem, many deterministic MMV algorithms solve the convex relaxed models with limited efficiency. In this paper, we develop stochastic greedy algorithms for solving the joint sparse MMV reconstruction problem. In particular, we propose the MMV Stochastic Iterative Hard Thresholding (MStoIHT) and MMV Stochastic Gradient Matching Pursuit (MStoGradMP) algorithms, and we also utilize the mini-batching technique to further improve their performance. Convergence analysis indicates that the proposed algorithms are able to converge faster than their SMV counterparts, i.e., concatenated StoIHT and StoGradMP, under certain conditions. Numerical experiments have illustrated the superior effectiveness of the proposed algorithms over their SMV counterparts.

preprint2020arXiv

Stochastic Iterative Hard Thresholding for Low-Tucker-Rank Tensor Recovery

Low-rank tensor recovery problems have been widely studied in many applications of signal processing and machine learning. Tucker decomposition is known as one of the most popular decompositions in the tensor framework. In recent years, researchers have developed many state-of-the-art algorithms to address the problem of low-Tucker-rank tensor recovery. Motivated by the favorable properties of the stochastic algorithms, such as stochastic gradient descent and stochastic iterative hard thresholding, we aim to extend the well-known stochastic iterative hard thresholding algorithm to the tensor framework in order to address the problem of recovering a low-Tucker-rank tensor from its linear measurements. We have also developed linear convergence analysis for the proposed method and conducted a series of experiments with both synthetic and real data to illustrate the performance of the proposed method.

preprint2020arXiv

Unsupervised Bidirectional Cross-Modality Adaptation via Deeply Synergistic Image and Feature Alignment for Medical Image Segmentation

Unsupervised domain adaptation has increasingly gained interest in medical image computing, aiming to tackle the performance degradation of deep neural networks when being deployed to unseen data with heterogeneous characteristics. In this work, we present a novel unsupervised domain adaptation framework, named as Synergistic Image and Feature Alignment (SIFA), to effectively adapt a segmentation network to an unlabeled target domain. Our proposed SIFA conducts synergistic alignment of domains from both image and feature perspectives. In particular, we simultaneously transform the appearance of images across domains and enhance domain-invariance of the extracted features by leveraging adversarial learning in multiple aspects and with a deeply supervised mechanism. The feature encoder is shared between both adaptive perspectives to leverage their mutual benefits via end-to-end learning. We have extensively evaluated our method with cardiac substructure segmentation and abdominal multi-organ segmentation for bidirectional cross-modality adaptation between MRI and CT images. Experimental results on two different tasks demonstrate that our SIFA method is effective in improving segmentation performance on unlabeled target images, and outperforms the state-of-the-art domain adaptation approaches by a large margin.

preprint2019arXiv

Direction-aware Spatial Context Features for Shadow Detection and Removal

Shadow detection and shadow removal are fundamental and challenging tasks, requiring an understanding of the global image semantics. This paper presents a novel deep neural network design for shadow detection and removal by analyzing the spatial image context in a direction-aware manner. To achieve this, we first formulate the direction-aware attention mechanism in a spatial recurrent neural network (RNN) by introducing attention weights when aggregating spatial context features in the RNN. By learning these weights through training, we can recover direction-aware spatial context (DSC) for detecting and removing shadows. This design is developed into the DSC module and embedded in a convolutional neural network (CNN) to learn the DSC features at different levels. Moreover, we design a weighted cross entropy loss to make effective the training for shadow detection and further adopt the network for shadow removal by using a Euclidean loss function and formulating a color transfer function to address the color and luminosity inconsistencies in the training pairs. We employed two shadow detection benchmark datasets and two shadow removal benchmark datasets, and performed various experiments to evaluate our method. Experimental results show that our method performs favorably against the state-of-the-art methods for both shadow detection and shadow removal.

preprint2019arXiv

Robust Matrix Completion via Maximum Correntropy Criterion and Half Quadratic Optimization

Robust matrix completion aims to recover a low-rank matrix from a subset of noisy entries perturbed by complex noises, where traditional methods for matrix completion may perform poorly due to utilizing $l_2$ error norm in optimization. In this paper, we propose a novel and fast robust matrix completion method based on maximum correntropy criterion (MCC). The correntropy based error measure is utilized instead of using $l_2$-based error norm to improve the robustness to noises. Using the half-quadratic optimization technique, the correntropy based optimization can be transformed to a weighted matrix factorization problem. Then, two efficient algorithms are derived, including alternating minimization based algorithm and alternating gradient descend based algorithm. The proposed algorithms do not need to calculate singular value decomposition (SVD) at each iteration. Further, the adaptive kernel selection strategy is proposed to accelerate the convergence speed as well as improve the performance. Comparison with existing robust matrix completion algorithms is provided by simulations, showing that the new methods can achieve better performance than existing state-of-the-art algorithms.

preprint2018arXiv

Direction-aware Spatial Context Features for Shadow Detection

Shadow detection is a fundamental and challenging task, since it requires an understanding of global image semantics and there are various backgrounds around shadows. This paper presents a novel network for shadow detection by analyzing image context in a direction-aware manner. To achieve this, we first formulate the direction-aware attention mechanism in a spatial recurrent neural network (RNN) by introducing attention weights when aggregating spatial context features in the RNN. By learning these weights through training, we can recover direction-aware spatial context (DSC) for detecting shadows. This design is developed into the DSC module and embedded in a CNN to learn DSC features at different levels. Moreover, a weighted cross entropy loss is designed to make the training more effective. We employ two common shadow detection benchmark datasets and perform various experiments to evaluate our network. Experimental results show that our network outperforms state-of-the-art methods and achieves 97% accuracy and 38% reduction on balance error rate.

preprint2018arXiv

SINet: A Scale-insensitive Convolutional Neural Network for Fast Vehicle Detection

Vision-based vehicle detection approaches achieve incredible success in recent years with the development of deep convolutional neural network (CNN). However, existing CNN based algorithms suffer from the problem that the convolutional features are scale-sensitive in object detection task but it is common that traffic images and videos contain vehicles with a large variance of scales. In this paper, we delve into the source of scale sensitivity, and reveal two key issues: 1) existing RoI pooling destroys the structure of small scale objects, 2) the large intra-class distance for a large variance of scales exceeds the representation capability of a single network. Based on these findings, we present a scale-insensitive convolutional neural network (SINet) for fast detecting vehicles with a large variance of scales. First, we present a context-aware RoI pooling to maintain the contextual information and original structure of small scale objects. Second, we present a multi-branch decision network to minimize the intra-class distance of features. These lightweight techniques bring zero extra time complexity but prominent detection accuracy improvement. The proposed techniques can be equipped with any deep network architectures and keep them trained end-to-end. Our SINet achieves state-of-the-art performance in terms of accuracy and speed (up to 37 FPS) on the KITTI benchmark and a new highway dataset, which contains a large variance of scales and extremely small objects.