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Yiming Chen

Yiming Chen contributes to research discovery and scholarly infrastructure.

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Published work

16 published item(s)

preprint2026arXiv

CLR-voyance: Reinforcing Open-Ended Reasoning for Inpatient Clinical Decision Support with Outcome-Aware Rubrics

Inpatient clinical reasoning is a sequential decision under partial observability: the clinician sees the admission so far and must choose the next action whose downstream consequences are not yet visible. Existing clinical-LLM evaluations and RL rewards signals collapse this into closed-form retrieval, clinical journey leakage, or unanchored LLM-as-judge scoring. We introduce CLR-voyance, a framework that reformulates inpatient reasoning as a Partially Observable Markov Decision Process (POMDP) and supervises it with rewards that are simultaneously outcome-grounded and clinician-validated. We instantiate the formulation as CLR-POMDP, which partitions successful patient journeys into a policy-visible past and an oracle-only future. Using the past information, an oracle LLM generates a case-specific query-answer pair, and the first adaptive rubric for clinical reasoning which is verifiable in the future of the patient journey. These rubrics are used for both post-training and evaluation of models for inpatient clinical reasoning. We post-train Qwen3-8B and MedGemma-4B with GRPO followed by model merging, yielding state-of-the-art inpatient clinical reasoning while retaining generalist capabilities. CLR-voyance-8B achieves 84.91% on CLR-POMDP, ahead of frontier medical reasoning models like GPT-5 (77.83%) and MedGemma-27B (66.66%) and has comparable or better performance on existing medical benchmarks. To ensure a clinically meaningful setting, we conduct a large-scale clinician alignment study, where physicians curate per-case rubrics, grade candidate responses, and provide blinded pairwise preferences of model reasoning. This study provides insights on clinical LLM-as-a-judge and clinical preference-model selection, which can inform the community at large. CLR-voyance has been deployed for 6+ months at a partner public hospital, drafting thousands of reasoning-heavy inpatient notes.

preprint2026arXiv

From Knowledge to Action: Outcomes of the 2025 Large Language Model (LLM) Hackathon for Applications in Materials Science and Chemistry

Large language models (LLMs) are rapidly changing how researchers in materials science and chemistry discover, organize, and act on scientific knowledge. This paper analyzes a broad set of community-developed LLM applications in an effort to identify emerging patterns in how these systems can be used across the scientific research lifecycle. We organize the projects into two complementary categories: Knowledge Infrastructure, systems that structure, retrieve, synthesize, and validate scientific information; and Action Systems, systems that execute, coordinate, or automate scientific work across computational and experimental environments. The submissions reveal a shift from single-purpose LLM tools toward integrated, multi-agent workflows that combine retrieval, reasoning, tool use, and domain-specific validation. Prominent themes include retrieval-augmented generation as grounding infrastructure, persistent structured knowledge representations, multimodal and multilingual scientific inputs, and early progress toward laboratory-integrated closed-loop systems. Together, these results suggest that LLMs are evolving from general-purpose assistants into composable infrastructure for scientific reasoning and action. This work provides a community snapshot of that transition and a practical taxonomy for understanding emerging LLM-enabled workflows in materials science and chemistry.

preprint2026arXiv

MORE: Multi-Objective Adversarial Attacks on Speech Recognition

The emergence of large-scale automatic speech recognition (ASR) models such as Whisper has greatly expanded their adoption across diverse real-world applications. Ensuring robustness against even minor input perturbations is therefore critical for maintaining reliable performance in real-time environments. While prior work has mainly examined accuracy degradation under adversarial attacks, robustness with respect to efficiency remains largely unexplored. This narrow focus provides only a partial understanding of ASR model vulnerabilities. To address this gap, we conduct a comprehensive study of ASR robustness under multiple attack scenarios. We introduce MORE, a multi-objective repetitive doubling encouragement attack, which jointly degrades recognition accuracy and inference efficiency through a hierarchical staged repulsion-anchoring mechanism. Specifically, we reformulate multi-objective adversarial optimization into a hierarchical framework that sequentially achieves the dual objectives. To further amplify effectiveness, we propose a novel repetitive encouragement doubling objective (REDO) that induces duplicative text generation by maintaining accuracy degradation and periodically doubling the predicted sequence length. Overall, MORE compels ASR models to produce incorrect transcriptions at a substantially higher computational cost, triggered by a single adversarial input. Experiments show that MORE consistently yields significantly longer transcriptions while maintaining high word error rates compared to existing baselines, underscoring its effectiveness in multi-objective adversarial attack.

preprint2026arXiv

ReMedi: Reasoner for Medical Clinical Prediction

Predicting future clinical outcomes from electronic health records (EHR) remains challenging due to the complexity and heterogeneity of patient data. LLMs have shown strong potential for such predictive tasks, yet existing approaches mainly focus on enhancing medical knowledge through distillation or RAG while relying on the model's internal ability to interpret contextual information. In this work, we present ReMedi (Reasoner for Medical Clinical Prediction), a framework for improving clinical outcome prediction from EHR. ReMedi generates rationale-answer pairs using a challenging sample regeneration mechanism for complex clinical questions, which leverages ground-truth answers as hints to enhance reasoning for further fine-tuning and preference tuning. ReMedi integrates ground-truth outcome guidance into the preference data construction loop, regenerating rationale-answer variants. By tuning on these rationale-answer pairs, the model improves its predictive performance. Experiments on multiple EHR prediction tasks demonstrate substantial gains of up to 19.9 percent over state-of-the-art baselines in terms of F1 score, underscoring ReMedi's effectiveness in real-world clinical prediction.

preprint2026arXiv

TreeDiff: AST-Guided Code Generation with Diffusion LLMs

Code generation is increasingly critical for real-world applications. Still, diffusion-based large language models continue to struggle with this demand. Unlike free-form text, code requires syntactic precision; even minor structural inconsistencies can render a program non-executable. Existing diffusion-based large language models rely on random token masking for corruption, leading to two key failures: they lack awareness of syntactic boundaries during the iterative denoising process, and they fail to capture the long-range hierarchical dependencies essential for program correctness. We propose TreeDiff to address both issues. Specifically, we propose a syntax-aware diffusion framework that incorporates structural priors from Abstract Syntax Tree (AST) into the corruption process. Instead of masking individual tokens at random, we selectively mask tokens belonging to key AST nodes. By aligning the corruption process with the underlying structure of code, our method encourages the model to internalize the compositional nature of programming languages, enabling it to reconstruct programs that respect grammatical boundaries and capture long-range dependencies. Our method achieves a 13.3% relative improvement over the random masking training method, demonstrating its effectiveness in code generation task by leveraging underlying structures.

preprint2025arXiv

A semicircle law for the normalized Laplacian of sparse random graphs

We study the limiting spectral distribution of the normalized Laplacian $\mathcal L$ of an Erdős-Rényi graph $G(n,p)$. To account for the presence of isolated vertices in the sparse regime, we define $\mathcal L$ using the Moore-Penrose pseudoinverse of the degree matrix. Under this convention, we show that the empirical spectral distribution of a suitably normalized $\mathcal L$ converges weakly in probability to the semicircle law whenever $np\to\infty$, thereby providing a rigorous justification of a prediction made in (Akara-pipattana and Evnin, 2023). Moreover, if $np>\log n+ω(1)$, so that $G(n,p)$ has no isolated vertices with high probability, the same conclusion holds for the standard definition of $\mathcal L$. We further strengthen this result to almost sure convergence when $np=Ω(\log n)$. Finally, we extend our approach to the Chung-Lu random graph model, where we establish a semicircle law for $\mathcal L$ itself, improving upon (Chung, Lu, and Vu 2003), which obtained the semicircle law only for a proxy matrix.

preprint2022arXiv

Deep learning-based photoacoustic imaging of vascular network through thick porous media

Photoacoustic imaging (PAI) is a promising approach to realize in vivo transcranial cerebral vascular imaging. However, the strong attenuation and distortion of the photoacoustic wave caused by the thick porous skull greatly affect the imaging quality. In this study, we designed a convolutional neural network (CNN) with a U-Net architecture to extract the effective photoacoustic information hidden in the speckle patterns; obtained vascular network images datasets under porous media through simulation and experiment, and trained the network weights respectively. The results show that the proposed neural network can learn the mapping relationship between the speckle pattern and the target; extract the photoacoustic signals of some vessels submerged in noise to reconstruct high-quality images with a sharp outline of the vessel and clean background. Compared with the traditional photoacoustic reconstruction method, the deep learning-based reconstruction algorithms can achieve better performance, the mean absolute error (MAE), Structural SIMilarity (SSIM) and peak signal-to-noise ratio (PSNR) of reconstructed images have been greatly improved. In conclusion, the proposed neural network can effectively extract valid information from highly blurred speckle patterns for the rapid reconstruction of target images, which offers promising applications in transcranial photoacoustic imaging.

preprint2022arXiv

FAST: A Fully-Concurrent Access Technique to All SRAM Rows for Enhanced Speed and Energy Efficiency in Data-Intensive Applications

Compute-in-memory (CiM) is a promising approach to improving the computing speed and energy efficiency in dataintensive applications. Beyond existing CiM techniques of bitwise logic-in-memory operations and dot product operations, this paper extends the CiM paradigm with FAST, a new shift-based inmemory computation technique to handle high-concurrency operations on multiple rows in an SRAM. Such high-concurrency operations are widely seen in both conventional applications (e.g. the table update in a database), and emerging applications (e.g. the parallel weight update in neural network accelerators), in which low latency and low energy consumption are critical. The proposed shift-based CiM architecture is enabled by integrating the shifter function into each SRAM cell, and by creating a datapath that exploits the high-parallelism of shifting operations in multiple rows in the array. A 128-row 16-column shiftable SRAM in 65nm CMOS is designed to evaluate the proposed architecture. Postlayout SPICE simulations show average improvements of 4.4x energy efficiency and 96.0x speed over a conventional fully-digital memory-computing-separated scheme, when performing the 8-bit weight update task in a VGG-7 framework.

preprint2022arXiv

GRAPHIC: GatheR-And-Process in Highly parallel with In-SSD Compression Architecture in Very Large-Scale Graph

Graph convolutional network (GCN), an emerging algorithm for graph computing, has achieved promising performance in graphstructure tasks. To achieve acceleration for data-intensive and sparse graph computing, ASICs such as GCNAX have been proposed for efficient execution of aggregation and combination in GCN. GCNAX reducing 8x DRAM accesses compared with previous efforts. However, as graphs have reached terabytes in size, off-chip data movement from SSD to DRAM becomes a serious latency bottleneck. This paper proposes Compressive Graph Transmission (CGTrans), which performs the aggregation in SSD to dramatically relieves the transfer latency bottleneck due to SSD loading compared to CMOS-based graph accelerator ASICs. InSSD computing technique is required for CGTrans. Recently, Insider was proposed as a near-SSD processing system computing by integrating FPGA in SSD. However, the Insider still suffers low area efficiency, which will limit the performance of CGTrans. The recently proposed Fully Concurrent Access Technique (FAST) is utilized. FAST-GAS, as an in-SSD graph computing accelerator, is proposed to provide high-concurrent gather-andscatter operations to overcome the area efficiency problem. We proposed the GRAPHIC system containing CGTrans dataflow deployed on FAST-GAS. Experiments show CGTrans reduces SSD loading by a factor of 50x, while GRAPHIC achieves 3.6x, and 2.4x speedup on average over GCNAX and CGTrans on Insider, respectively.

preprint2022arXiv

Spectral form factor for free large $N$ gauge theory and strings

We investigate the spectral form factor in two different systems, free large $N$ gauge theories and highly excited string gas. In both cases, after a rapid decay of the spectral form factor at early time, new contributions come in, preventing the spectral form factor from ever becoming exponentially small. We consider $U(N)$ gauge theories with only adjoint matter and compute the spectral form factor using a matrix integral of the thermal holonomy $U$. The new saddles differ from the early time saddle by preserving certain subgroups of the center symmetry. For a gas of strings, the short time decay of the spectral form factor is governed by the continuous Hagedorn density of states, which can be associated to the thermal winding mode with winding number $\pm 1$. We show that the rise of the spectral form factor comes from other winding modes that also carry momentum along the time direction. We speculate on the existence of a family of classical solutions for these string modes, similar to the Horowitz-Polchinski solution. We review a similar problem for black holes. In particular, we examine the Kontsevich-Segal criterion on complex black holes that contribute to the spectral form factor. In the canonical ensemble quantity $Z(β+it)$, the black hole becomes unallowed at $t\sim \mathcal{O}(β)$. A way to avoid this is to consider the microcanonical ensemble, where the black hole stays allowable.

preprint2022arXiv

YOLoC: DeploY Large-Scale Neural Network by ROM-based Computing-in-Memory using ResiduaL Branch on a Chip

Computing-in-memory (CiM) is a promising technique to achieve high energy efficiency in data-intensive matrix-vector multiplication (MVM) by relieving the memory bottleneck. Unfortunately, due to the limited SRAM capacity, existing SRAM-based CiM needs to reload the weights from DRAM in large-scale networks. This undesired fact weakens the energy efficiency significantly. This work, for the first time, proposes the concept, design, and optimization of computing-in-ROM to achieve much higher on-chip memory capacity, and thus less DRAM access and lower energy consumption. Furthermore, to support different computing scenarios with varying weights, a weight fine-tune technique, namely Residual Branch (ReBranch), is also proposed. ReBranch combines ROM-CiM and assisting SRAM-CiM to ahieve high versatility. YOLoC, a ReBranch-assisted ROM-CiM framework for object detection is presented and evaluated. With the same area in 28nm CMOS, YOLoC for several datasets has shown significant energy efficiency improvement by 14.8x for YOLO (Darknet-19) and 4.8x for ResNet-18, with <8% latency overhead and almost no mean average precision (mAP) loss (-0.5% ~ +0.2%), compared with the fully SRAM-based CiM.

preprint2021arXiv

Large-Scale Training System for 100-Million Classification at Alibaba

In the last decades, extreme classification has become an essential topic for deep learning. It has achieved great success in many areas, especially in computer vision and natural language processing (NLP). However, it is very challenging to train a deep model with millions of classes due to the memory and computation explosion in the last output layer. In this paper, we propose a large-scale training system to address these challenges. First, we build a hybrid parallel training framework to make the training process feasible. Second, we propose a novel softmax variation named KNN softmax, which reduces both the GPU memory consumption and computation costs and improves the throughput of training. Then, to eliminate the communication overhead, we propose a new overlapping pipeline and a gradient sparsification method. Furthermore, we design a fast continuous convergence strategy to reduce total training iterations by adaptively adjusting learning rate and updating model parameters. With the help of all the proposed methods, we gain 3.9$\times$ throughput of our training system and reduce almost 60\% of training iterations. The experimental results show that using an in-house 256 GPUs cluster, we could train a classifier of 100 million classes on Alibaba Retail Product Dataset in about five days while achieving a comparable accuracy with the naive softmax training process.

preprint2021arXiv

String scale black holes at large $D$

We study aspects of black holes near the Hagedorn temperature. The large dimension expansion introduced by Soda, Emparan, Grumiller and Tanabe connects them to the well studied two dimensional black hole based on $SL(2)_k/U(1)$. This allows us to explore black holes at string scale temperatures. We argue that the black hole can surpass the Hagedorn temperature, but at a somewhat larger temperature it is likely to turn over to a highly excited string.

preprint2020arXiv

A Lightweight and Accurate Localization Algorithm Using Multiple Inertial Measurement Units

This paper proposes a novel inertial-aided localization approach by fusing information from multiple inertial measurement units (IMUs) and exteroceptive sensors. IMU is a low-cost motion sensor which provides measurements on angular velocity and gravity compensated linear acceleration of a moving platform, and widely used in modern localization systems. To date, most existing inertial-aided localization methods exploit only one single IMU. While the single-IMU localization yields acceptable accuracy and robustness for different use cases, the overall performance can be further improved by using multiple IMUs. To this end, we propose a lightweight and accurate algorithm for fusing measurements from multiple IMUs and exteroceptive sensors, which is able to obtain noticeable performance gain without incurring additional computational cost. To achieve this, we first probabilistically map measurements from all IMUs onto a virtual IMU. This step is performed by stochastic estimation with least-square estimators and probabilistic marginalization of inter-IMU rotational accelerations. Subsequently, the propagation model for both state and error state of the virtual IMU is also derived, which enables the use of the classical filter-based or optimization-based sensor fusion algorithms for localization. Finally, results from both simulation and real-world tests are provided, which demonstrate that the proposed algorithm outperforms competing algorithms by noticeable margins.

preprint2020arXiv

Pulling Out the Island with Modular Flow

Recent works have suggested that the entanglement wedge of Hawking radiation coming from an AdS black hole, will include an island inside the black hole interior after the Page time. In this paper, we propose a concrete way to extract the information from the island by acting only on the radiation degrees of freedom, building on the equivalence between the boundary and bulk modular flow. We consider examples with black holes in JT gravity coupled to baths. In the case that the bulk conformal fields contain free massless fermion field, we provide explicit bulk picture of the information extraction process, where we find that one can almost pull out an operator from the island to the bath with modular flow.

preprint2019arXiv

A Performance and Cost Assessment of Machine Learning Interatomic Potentials

Machine learning of the quantitative relationship between local environment descriptors and the potential energy surface of a system of atoms has emerged as a new frontier in the development of interatomic potentials (IAPs). Here, we present a comprehensive evaluation of ML-IAPs based on four local environment descriptors --- Behler-Parrinello symmetry functions, smooth overlap of atomic positions (SOAP), the Spectral Neighbor Analysis Potential (SNAP) bispectrum components, and moment tensors --- using a diverse data set generated using high-throughput density functional theory (DFT) calculations. The data set comprising bcc (Li, Mo) and fcc (Cu, Ni) metals and diamond group IV semiconductors (Si, Ge) is chosen to span a range of crystal structures and bonding. All descriptors studied show excellent performance in predicting energies and forces far surpassing that of classical IAPs, as well as predicting properties such as elastic constants and phonon dispersion curves. We observe a general trade-off between accuracy and the degrees of freedom of each model, and consequently computational cost. We will discuss these trade-offs in the context of model selection for molecular dynamics and other applications.