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Quan Lu

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Published work

6 published item(s)

preprint2026arXiv

BioProVLA-Agent: An Affordable, Protocol-Driven, Vision-Enhanced VLA-Enabled Embodied Multi-Agent System with Closed-Loop-Capable Reasoning for Biological Laboratory Manipulation

Biological laboratory automation can reduce repetitive manual work and improve reproducibility, but reliable embodied execution in wet-lab environments remains challenging. Protocols are often unstructured, labware is frequently transparent or reflective, and multi-step procedures require state-aware execution beyond one-shot instruction following. Existing robotic systems often rely on costly hardware, fixed workflows, dedicated instruments, or robotics-oriented interfaces. Here, we introduce BioProVLA-Agent, an affordable, protocol-driven, vision-enhanced embodied multi-agent system enabled by Vision-Language-Action (VLA) models for biological manipulation. The system uses protocols as the task interface and integrates protocol parsing, visual state verification, and embodied execution in a closed-loop workflow. A Tailored LLM Protocol Agent converts protocols into verifiable subtasks; a VLM-RAG Verification Agent assesses readiness and completion using observations, robot states, retrieved knowledge, and success/failure examples; and a VLA Embodied Agent executes verified subtasks through a lightweight policy. To improve robustness under wet-lab visual perturbations, we develop AugSmolVLA, an online augmentation strategy targeting transparent labware, reflections, illumination shifts, and overexposure. We evaluate the system on a hierarchical benchmark covering 15 atomic tasks, 6 composite workflows, and 3 bimanual tasks, including tube loading, sorting, waste disposal, cap twisting, and liquid pouring. Across normal and high-exposure settings, AugSmolVLA improves execution stability over ACT, X-VLA, and the original SmolVLA, especially for precise placement, transparent-object manipulation, composite workflows, and visually degraded scenes. These results suggest a practical route toward accessible, protocol-centered, and verification-capable embodied AI for biological manipulation.

preprint2022arXiv

Modeling Price Elasticity for Occupancy Prediction in Hotel Dynamic Pricing

Demand estimation plays an important role in dynamic pricing where the optimal price can be obtained via maximizing the revenue based on the demand curve. In online hotel booking platform, the demand or occupancy of rooms varies across room-types and changes over time, and thus it is challenging to get an accurate occupancy estimate. In this paper, we propose a novel hotel demand function that explicitly models the price elasticity of demand for occupancy prediction, and design a price elasticity prediction model to learn the dynamic price elasticity coefficient from a variety of affecting factors. Our model is composed of carefully designed elasticity learning modules to alleviate the endogeneity problem, and trained in a multi-task framework to tackle the data sparseness. We conduct comprehensive experiments on real-world datasets and validate the superiority of our method over the state-of-the-art baselines for both occupancy prediction and dynamic pricing.

preprint2020arXiv

Field-weighted Factorization Machines for Click-Through Rate Prediction in Display Advertising

Click-through rate (CTR) prediction is a critical task in online display advertising. The data involved in CTR prediction are typically multi-field categorical data, i.e., every feature is categorical and belongs to one and only one field. One of the interesting characteristics of such data is that features from one field often interact differently with features from different other fields. Recently, Field-aware Factorization Machines (FFMs) have been among the best performing models for CTR prediction by explicitly modeling such difference. However, the number of parameters in FFMs is in the order of feature number times field number, which is unacceptable in the real-world production systems. In this paper, we propose Field-weighted Factorization Machines (FwFMs) to model the different feature interactions between different fields in a much more memory-efficient way. Our experimental evaluations show that FwFMs can achieve competitive prediction performance with only as few as 4% parameters of FFMs. When using the same number of parameters, FwFMs can bring 0.92% and 0.47% AUC lift over FFMs on two real CTR prediction data sets.

preprint2020arXiv

Sharp Multiple Instance Learning for DeepFake Video Detection

With the rapid development of facial manipulation techniques, face forgery has received considerable attention in multimedia and computer vision community due to security concerns. Existing methods are mostly designed for single-frame detection trained with precise image-level labels or for video-level prediction by only modeling the inter-frame inconsistency, leaving potential high risks for DeepFake attackers. In this paper, we introduce a new problem of partial face attack in DeepFake video, where only video-level labels are provided but not all the faces in the fake videos are manipulated. We address this problem by multiple instance learning framework, treating faces and input video as instances and bag respectively. A sharp MIL (S-MIL) is proposed which builds direct mapping from instance embeddings to bag prediction, rather than from instance embeddings to instance prediction and then to bag prediction in traditional MIL. Theoretical analysis proves that the gradient vanishing in traditional MIL is relieved in S-MIL. To generate instances that can accurately incorporate the partially manipulated faces, spatial-temporal encoded instance is designed to fully model the intra-frame and inter-frame inconsistency, which further helps to promote the detection performance. We also construct a new dataset FFPMS for partially attacked DeepFake video detection, which can benefit the evaluation of different methods at both frame and video levels. Experiments on FFPMS and the widely used DFDC dataset verify that S-MIL is superior to other counterparts for partially attacked DeepFake video detection. In addition, S-MIL can also be adapted to traditional DeepFake image detection tasks and achieve state-of-the-art performance on single-frame datasets.

preprint2016arXiv

Lift-Based Bidding in Ad Selection

Real-time bidding (RTB) has become one of the largest online advertising markets in the world. Today the bid price per ad impression is typically decided by the expected value of how it can lead to a desired action event (e.g., registering an account or placing a purchase order) to the advertiser. However, this industry standard approach to decide the bid price does not consider the actual effect of the ad shown to the user, which should be measured based on the performance lift among users who have been or have not been exposed to a certain treatment of ads. In this paper, we propose a new bidding strategy and prove that if the bid price is decided based on the performance lift rather than absolute performance value, advertisers can actually gain more action events. We describe the modeling methodology to predict the performance lift and demonstrate the actual performance gain through blind A/B test with real ad campaigns in an industry-leading Demand-Side Platform (DSP). We also discuss the relationship between attribution models and bidding strategies. We prove that, to move the DSPs to bid based on performance lift, they should be rewarded according to the relative performance lift they contribute.

preprint2015arXiv

Smart Pacing for Effective Online Ad Campaign Optimization

In targeted online advertising, advertisers look for maximizing campaign performance under delivery constraint within budget schedule. Most of the advertisers typically prefer to impose the delivery constraint to spend budget smoothly over the time in order to reach a wider range of audiences and have a sustainable impact. Since lots of impressions are traded through public auctions for online advertising today, the liquidity makes price elasticity and bid landscape between demand and supply change quite dynamically. Therefore, it is challenging to perform smooth pacing control and maximize campaign performance simultaneously. In this paper, we propose a smart pacing approach in which the delivery pace of each campaign is learned from both offline and online data to achieve smooth delivery and optimal performance goals. The implementation of the proposed approach in a real DSP system is also presented. Experimental evaluations on both real online ad campaigns and offline simulations show that our approach can effectively improve campaign performance and achieve delivery goals.