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Researcher profile

Hu Chen

Hu Chen contributes to research discovery and scholarly infrastructure.

ResearcherAffiliation not importedOpen to collaborate
physics.med-phComputer Visioneess.IVBiological PhysicsBiomoleculesComputation and Languagecond-mat.softeess.ASMachine Learningphysics.opticsquant-phSound

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Published work

9 published item(s)

preprint2026arXiv

PULSE: Generative Phase Evolution for Non-Stationary Time Series Forecasting

Time series forecasting under non-stationarity faces a fundamental tension between capturing stable representations and adapting to distribution shifts. Existing methods implicitly rely on static historical assumptions, leading to a critical failure mode we term Phase Amnesia, where models become blind to the evolving global context. To resolve this, we formalize non-stationary dynamics through three physical hypotheses: wold decomposition, dynamical phase evolution, and heteroscedastic manifold generation. These principles inspire PULSE, a physics-informed, plug-and-play framework adopting a Disentangle--Evolve--Simulate design philosophy. Specifically, PULSE utilizes phase-anchored disentanglement to resolve optimization interference caused by dominant trends, employs a Phase Router to actively generate future trajectories, and introduces Statistic-Aware Mixup (SAM) to ensure robustness against out-of-distribution volatility. Empirically, PULSE enables a simple MLP backbone to achieve state-of-the-art or highly competitive performance across 12 real-world benchmarks. This validates that a correct physics-informed inductive bias is far more critical than raw architectural complexity for non-stationary forecasting. The code is available at: https://github.com/Gemost/PULSE.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Depth Completion using Geometry-Aware Embedding

Exploiting internal spatial geometric constraints of sparse LiDARs is beneficial to depth completion, however, has been not explored well. This paper proposes an efficient method to learn geometry-aware embedding, which encodes the local and global geometric structure information from 3D points, e.g., scene layout, object's sizes and shapes, to guide dense depth estimation. Specifically, we utilize the dynamic graph representation to model generalized geometric relationship from irregular point clouds in a flexible and efficient manner. Further, we joint this embedding and corresponded RGB appearance information to infer missing depths of the scene with well structure-preserved details. The key to our method is to integrate implicit 3D geometric representation into a 2D learning architecture, which leads to a better trade-off between the performance and efficiency. Extensive experiments demonstrate that the proposed method outperforms previous works and could reconstruct fine depths with crisp boundaries in regions that are over-smoothed by them. The ablation study gives more insights into our method that could achieve significant gains with a simple design, while having better generalization capability and stability. The code is available at https://github.com/Wenchao-Du/GAENet.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Free energy landscape of two-state protein Acylphosphatase with large contact order revealed by force-dependent folding and unfolding dynamics

Acylphosphatase (AcP) is a small protein with 98 amino acid residues that catalyzes the hydrolysis of carboxyl-phosphate bonds. AcP is a typical two-state protein with slow folding rate due to its relatively large contact order in the native structure. The mechanical properties and unfolding behavior of AcP has been studied by atomic force microscope. But the folding and unfolding dynamics at low forces has not been reported. Here using stable magnetic tweezers, we measured the force-dependent folding rates within a force range from 1 pN to 3 pN, and unfolding rates from 15 pN to 40 pN. The obtained unfolding rates show different force sensitivities at forces below and above ~27 pN, which determines a free energy landscape with two energy barriers. Our results indicate that the free energy landscape of small globule proteins have general Bactrian camel shape, and large contact order of the native state produces a high barrier dominate at low forces.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

SOUL-Net: A Sparse and Low-Rank Unrolling Network for Spectral CT Image Reconstruction

Spectral computed tomography (CT) is an emerging technology, that generates a multienergy attenuation map for the interior of an object and extends the traditional image volume into a 4D form. Compared with traditional CT based on energy-integrating detectors, spectral CT can make full use of spectral information, resulting in high resolution and providing accurate material quantification. Numerous model-based iterative reconstruction methods have been proposed for spectral CT reconstruction. However, these methods usually suffer from difficulties such as laborious parameter selection and expensive computational costs. In addition, due to the image similarity of different energy bins, spectral CT usually implies a strong low-rank prior, which has been widely adopted in current iterative reconstruction models. Singular value thresholding (SVT) is an effective algorithm to solve the low-rank constrained model. However, the SVT method requires manual selection of thresholds, which may lead to suboptimal results. To relieve these problems, in this paper, we propose a Sparse and lOw-rank UnroLling Network for spectral CT image reconstruction (SOUL-Net), that learns the parameters and thresholds in a data-driven manner. Furthermore, a Taylor expansion-based neural network backpropagation method is introduced to improve the numerical stability. The qualitative and quantitative results demonstrate that the proposed method outperforms several representative state-of-the-art algorithms in terms of detail preservation and artifact reduction.

0 citations0 reviewsNo code linkedOpen access
preprint2021arXiv

ATCSpeechNet: A multilingual end-to-end speech recognition framework for air traffic control systems

In this paper, a multilingual end-to-end framework, called as ATCSpeechNet, is proposed to tackle the issue of translating communication speech into human-readable text in air traffic control (ATC) systems. In the proposed framework, we focus on integrating the multilingual automatic speech recognition (ASR) into one model, in which an end-to-end paradigm is developed to convert speech waveform into text directly, without any feature engineering or lexicon. In order to make up for the deficiency of the handcrafted feature engineering caused by ATC challenges, a speech representation learning (SRL) network is proposed to capture robust and discriminative speech representations from the raw wave. The self-supervised training strategy is adopted to optimize the SRL network from unlabeled data, and further to predict the speech features, i.e., wave-to-feature. An end-to-end architecture is improved to complete the ASR task, in which a grapheme-based modeling unit is applied to address the multilingual ASR issue. Facing the problem of small transcribed samples in the ATC domain, an unsupervised approach with mask prediction is applied to pre-train the backbone network of the ASR model on unlabeled data by a feature-to-feature process. Finally, by integrating the SRL with ASR, an end-to-end multilingual ASR framework is formulated in a supervised manner, which is able to translate the raw wave into text in one model, i.e., wave-to-text. Experimental results on the ATCSpeech corpus demonstrate that the proposed approach achieves a high performance with a very small labeled corpus and less resource consumption, only 4.20% label error rate on the 58-hour transcribed corpus. Compared to the baseline model, the proposed approach obtains over 100% relative performance improvement which can be further enhanced with the increasing of the size of the transcribed samples.

0 citations0 reviewsNo code linkedOpen access
preprint2021arXiv

Testing real quantum theory in an optical quantum network

Quantum theory is commonly formulated in complex Hilbert spaces. However, the question of whether complex numbers need to be given a fundamental role in the theory has been debated since its pioneering days. Recently it has been shown that tests in the spirit of a Bell inequality can reveal quantum predictions in entanglement swapping scenarios that cannot be modelled by the natural real-number analog of standard quantum theory. Here, we tailor such tests for implementation in state-of-the-art photonic systems. We experimentally demonstrate quantum correlations in a network of three parties and two independent EPR sources that violate the constraints of real quantum theory by over $4.5$ standard deviations, hence disproving real quantum theory as a universal physical theory.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Learning Invariant Representation for Unsupervised Image Restoration

Recently, cross domain transfer has been applied for unsupervised image restoration tasks. However, directly applying existing frameworks would lead to domain-shift problems in translated images due to lack of effective supervision. Instead, we propose an unsupervised learning method that explicitly learns invariant presentation from noisy data and reconstructs clear observations. To do so, we introduce discrete disentangling representation and adversarial domain adaption into general domain transfer framework, aided by extra self-supervised modules including background and semantic consistency constraints, learning robust representation under dual domain constraints, such as feature and image domains. Experiments on synthetic and real noise removal tasks show the proposed method achieves comparable performance with other state-of-the-art supervised and unsupervised methods, while having faster and stable convergence than other domain adaption methods.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

MAGIC: Manifold and Graph Integrative Convolutional Network for Low-Dose CT Reconstruction

Low-dose computed tomography (LDCT) scans, which can effectively alleviate the radiation problem, will degrade the imaging quality. In this paper, we propose a novel LDCT reconstruction network that unrolls the iterative scheme and performs in both image and manifold spaces. Because patch manifolds of medical images have low-dimensional structures, we can build graphs from the manifolds. Then, we simultaneously leverage the spatial convolution to extract the local pixel-level features from the images and incorporate the graph convolution to analyze the nonlocal topological features in manifold space. The experiments show that our proposed method outperforms both the quantitative and qualitative aspects of state-of-the-art methods. In addition, aided by a projection loss component, our proposed method also demonstrates superior performance for semi-supervised learning. The network can remove most noise while maintaining the details of only 10% (40 slices) of the training data labeled.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Noise-Powered Disentangled Representation for Unsupervised Speckle Reduction of Optical Coherence Tomography Images

Due to its noninvasive character, optical coherence tomography (OCT) has become a popular diagnostic method in clinical settings. However, the low-coherence interferometric imaging procedure is inevitably contaminated by heavy speckle noise, which impairs both visual quality and diagnosis of various ocular diseases. Although deep learning has been applied for image denoising and achieved promising results, the lack of well-registered clean and noisy image pairs makes it impractical for supervised learning-based approaches to achieve satisfactory OCT image denoising results. In this paper, we propose an unsupervised OCT image speckle reduction algorithm that does not rely on well-registered image pairs. Specifically, by employing the ideas of disentangled representation and generative adversarial network, the proposed method first disentangles the noisy image into content and noise spaces by corresponding encoders. Then, the generator is used to predict the denoised OCT image with the extracted content features. In addition, the noise patches cropped from the noisy image are utilized to facilitate more accurate disentanglement. Extensive experiments have been conducted, and the results suggest that our proposed method is superior to the classic methods and demonstrates competitive performance to several recently proposed learning-based approaches in both quantitative and qualitative aspects.

0 citations0 reviewsNo code linkedOpen access