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Gianluca Palermo

Gianluca Palermo contributes to research discovery and scholarly infrastructure.

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Published work

3 published item(s)

preprint2026arXiv

EnergyLens: Interpretable Closed-Form Energy Models for Multimodal LLM Inference Serving

As large language models span dense, mixture-of-experts, and state-space architectures and are deployed on heterogeneous accelerators under increasingly diverse multimodal workloads, optimising inference energy has become as critical as optimizing latency and throughput. Existing approaches either treat latency as an energy proxy or rely on data-hungry black-box surrogates. Both fail under varying parallelism strategies: latency and energy optima diverge in over 20% of configurations we tested, and black-box surrogates require hundreds of profiling samples to generalize across model families and hardware. We present EnergyLens, which uses symbolic regression as a structure-discovery tool over profiling data to derive a single twelve-parameter closed-form energy model expressed in terms of system properties such as degree of parallelism, batch size, and sequence length. Unlike black-box surrogates, EnergyLens decouples tensor and pipeline parallelism contributions and separates prefill from decode energy, making its predictions physically interpretable and actionable. Fitted from as few as 50 profiling measurements, EnergyLens achieves 88.2% Top-1 configuration selection accuracy across many evaluation scenarios compared to 60.9% for the closest prior analytical baseline, matches the predictive accuracy of ensemble ML methods with 10x fewer profiling samples, and extrapolates reliably to unseen batch sizes and hardware platforms without structural modification, making it a practical, interpretable tool for energy-optimal LLM deployment.

preprint2022arXiv

GPU-optimized Approaches to Molecular Docking-based Virtual Screening in Drug Discovery: A Comparative Analysis

COVID-19 has shown the importance of having a fast response against pandemics. Finding a novel drug is a very long and complex procedure, and it is possible to accelerate the preliminary phases by using computer simulations. In particular, virtual screening is an in-silico phase that is needed to filter a large set of possible drug candidates to a manageable number. This paper presents the implementations and a comparative analysis of two GPU-optimized implementations of a virtual screening algorithm targeting novel GPU architectures. The first adopts a traditional approach that spreads the computation required to evaluate a single molecule across the entire GPU. The second uses a batched approach that exploits the parallel architecture of the GPU to evaluate more molecules in parallel, without considering the latency to process a single molecule. The paper describes the advantages and disadvantages of the proposed solutions, highlighting implementation details that impact the performance. Experimental results highlight the different performance of the two methods on several target molecule databases while running on NVIDIA A100 GPUs. The two implementations have a strong dependency with respect to the data to be processed. For both cases, the performance is improving while reducing the dimension of the target molecules (number of atoms and rotatable bonds). The two methods demonstrated a different behavior with respect to the size of the molecule database to be screened. While the latency one reaches sooner (with fewer molecules) the performance plateau in terms of throughput, the batched one requires a larger set of molecules. However, the performances after the initial transient period are much higher (up to 5x speed-up). Finally, to check the efficiency of both implementations we deeply analyzed their workload characteristics using the instruction roof-line methodology.

preprint2020arXiv

A Collaborative Filtering Approach for the Automatic Tuning of Compiler Optimisations

Selecting the right compiler optimisations has a severe impact on programs' performance. Still, the available optimisations keep increasing, and their effect depends on the specific program, making the task human intractable. Researchers proposed several techniques to search in the space of compiler optimisations. Some approaches focus on finding better search algorithms, while others try to speed up the search by leveraging previously collected knowledge. The possibility to effectively reuse previous compilation results inspired us toward the investigation of techniques derived from the Recommender Systems field. The proposed approach exploits previously collected knowledge and improves its characterisation over time. Differently from current state-of-the-art solutions, our approach is not based on performance counters but relies on Reaction Matching, an algorithm able to characterise programs looking at how they react to different optimisation sets. The proposed approach has been validated using two widely used benchmark suites, cBench and PolyBench, including 54 different programs. Our solution, on average, extracted 90% of the available performance improvement 10 iterations before current state-of-the-art solutions, which corresponds to 40% fewer compilations and performance tests to perform.