Researcher profile

Anru R. Zhang

Anru R. Zhang contributes to research discovery and scholarly infrastructure.

ResearcherAffiliation not importedOpen to collaborate

Trust snapshot

Quick read

Trust 21 - EmergingVerification L1Unclaimed author
13works
0followers
13topics
4close collaborators

Actions

Decide how to stay connected

Follow researcher0

Identity and collaboration

How to connect with this researcher

Claiming links this public author record to a researcher profile and unlocks direct collaboration workflows.

Log in to claim

Direct collaboration

Open a focused conversation when the fit is right

Claim this author entity first to unlock direct invitations.

Research graph

See the researcher in context

Open full explorer

Inspect adjacent work, topics, institutions and collaborators without jumping out to a separate graph page.

Building this graph slice

BZPEER is loading the nearby papers, people, topics and institutions for this page.

Published work

13 published item(s)

preprint2026arXiv

Coupling Models for One-Step Discrete Generation

Generative modeling over discrete structures underpins applications across deep learning, from biological sequence design and code generation to large language models, yet generation often remains sequential, relying on autoregressive decoding or iterative refinement. In this work, we introduce Coupling Models(Coupling Models), a one-step discrete generative model that learns a direct coupling between discrete sequences and Gaussian latents. Unlike recent distillation methods that compress a pretrained multi-step sampler into a few steps, Coupling Model trains a purpose-built decoder to invert this coupling and generate samples in a single step. The model also avoids complex continuous flows over the simplex and hand-specified data-to-noise couplings. Empirically,Coupling Model improves the strongest one-step baselines in each domain: it reduces LM1B text-generation perplexity by 33% at its lowest-perplexity operating point, Fly Brain enhancer-design FBD by 18%, and MNIST-Binary FID by 46%. These results suggest that effective one-step discrete generation depends strongly on how data and noise are coupled before decoding. Code is available at https://github.com/pengzhangzhi/Coupling-Models.

preprint2026arXiv

Don't Retrain, Align: Adapting Autoregressive LMs to Diffusion LMs via Representation Alignment

Diffusion language models (DLMs) have recently demonstrated capabilities that complement standard autoregressive (AR) models, particularly in non-sequential generation and bidirectional editing. Although recent work has shown that pretrained autoregressive checkpoints can be converted into diffusion language models, existing recipes primarily transfer parameters through continued denoising training with objective- and attention-level modifications. We instead ask whether the internal representation geometry learned by next-token prediction can be explicitly preserved during AR-to-DLM conversion. We hypothesize that much of the semantic structure learned by AR pretraining can transfer across generation orders, and thus DLM training should be viewed as relearning the decoding path rather than relearning language representations. To investigate this, we introduce REPR-ALIGN, a representation alignment objective that adapts a bidirectional masked diffusion model to reuse representations from a pretrained AR model of identical architecture. Concretely, we align the hidden states of the DLM to the frozen AR model at every layer using cosine similarity, while optimizing the standard masked denoising objective. This simple alignment, with no adapters and no architectural changes beyond the attention mask, yields up to 4x training acceleration in our setting and is particularly effective in low-data regimes. Our results suggest that linguistic representations can transfer across generation order, and that representation alignment provides a simple and effective technique for training diffusion language models. Code is available at https://github.com/pengzhangzhi/Open-dLLM.

preprint2026arXiv

Statistical Inference for Fuzzy Clustering

Clustering is a central tool in biomedical research for discovering heterogeneous patient subpopulations, where group boundaries are often diffuse rather than sharply separated. Traditional methods produce hard partitions, whereas soft clustering methods such as fuzzy $c$-means (FCM) allow mixed memberships and better capture uncertainty and gradual transitions. Despite the widespread use of FCM, principled statistical inference for fuzzy clustering remains limited. We develop a new framework for weighted fuzzy $c$-means (WFCM) for settings with potential cluster size imbalance. Cluster-specific weights rebalance the classical FCM criterion so that smaller clusters are not overwhelmed by dominant groups, and the weighted objective induces a normalized density model with scale parameter $σ$ and fuzziness parameter $m$. Estimation is performed via a blockwise majorize--minimize (MM) procedure that alternates closed-form membership and centroid updates with likelihood-based updates of $(σ,\bw)$. The intractable normalizing constant is approximated by importance sampling using a data-adaptive Gaussian mixture proposal. We further provide likelihood ratio tests for comparing cluster centers and bootstrap-based confidence intervals. We establish consistency and asymptotic normality of the maximum likelihood estimator, validate the method through simulations, and illustrate it using single-cell RNA-seq and Alzheimer disease Neuroimaging Initiative (ADNI) data. These applications demonstrate stable uncertainty quantification and biologically meaningful soft memberships, ranging from well-separated cell populations under imbalance to a graded AD versus non-AD continuum consistent with disease progression.

preprint2025arXiv

Subtype-Aware Registration of Longitudinal Electronic Health Records

Electronic Health Records (EHRs) contain extensive patient information that can inform downstream clinical decisions, such as mortality prediction, disease phenotyping, and disease onset prediction. A key challenge in EHR data analysis is the temporal gap between when a condition is first recorded and its actual onset time. Such timeline misalignment can lead to artificially distinct biomarker trends among patients with similar disease progression, undermining the reliability of downstream analyses and complicating tasks such as disease subtyping and outcome prediction. To address this challenge, we provide a subtype-aware timeline registration method that leverages data projection and discrete optimization to correct timeline misalignment. Through simulation and real-world data analyses, we demonstrate that the proposed method effectively aligns distorted observed records with the true disease progression patterns, enhancing subtyping clarity and improving performance in downstream clinical analyses.

preprint2022arXiv

Core Shrinkage Covariance Estimation for Matrix-variate Data

A separable covariance model for a random matrix provides a parsimonious description of the covariances among the rows and among the columns of the matrix, and permits likelihood-based inference with a very small sample size. However, in many applications the assumption of exact separability is unlikely to be met, and data analysis with a separable model may overlook or misrepresent important dependence patterns in the data. In this article, we propose a compromise between separable and unstructured covariance estimation. We show how the set of covariance matrices may be uniquely parametrized in terms of the set of separable covariance matrices and a complementary set of "core" covariance matrices, where the core of a separable covariance matrix is the identity matrix. This parametrization defines a Kronecker-core decomposition of a covariance matrix. By shrinking the core of the sample covariance matrix with an empirical Bayes procedure, we obtain an estimator that can adapt to the degree of separability of the population covariance matrix.

preprint2022arXiv

Learning Polynomial Transformations

We consider the problem of learning high dimensional polynomial transformations of Gaussians. Given samples of the form $p(x)$, where $x\sim N(0, \mathrm{Id}_r)$ is hidden and $p: \mathbb{R}^r \to \mathbb{R}^d$ is a function where every output coordinate is a low-degree polynomial, the goal is to learn the distribution over $p(x)$. This problem is natural in its own right, but is also an important special case of learning deep generative models, namely pushforwards of Gaussians under two-layer neural networks with polynomial activations. Understanding the learnability of such generative models is crucial to understanding why they perform so well in practice. Our first main result is a polynomial-time algorithm for learning quadratic transformations of Gaussians in a smoothed setting. Our second main result is a polynomial-time algorithm for learning constant-degree polynomial transformations of Gaussian in a smoothed setting, when the rank of the associated tensors is small. In fact our results extend to any rotation-invariant input distribution, not just Gaussian. These are the first end-to-end guarantees for learning a pushforward under a neural network with more than one layer. Along the way, we also give the first polynomial-time algorithms with provable guarantees for tensor ring decomposition, a popular generalization of tensor decomposition that is used in practice to implicitly store large tensors.

preprint2022arXiv

On the Non-Asymptotic Concentration of Heteroskedastic Wishart-type Matrix

This paper focuses on the non-asymptotic concentration of the heteroskedastic Wishart-type matrices. Suppose $Z$ is a $p_1$-by-$p_2$ random matrix and $Z_{ij} \sim N(0,σ_{ij}^2)$ independently, we prove the expected spectral norm of Wishart matrix deviations (i.e., $\mathbb{E} \left\|ZZ^\top - \mathbb{E} ZZ^\top\right\|$) is upper bounded by \begin{equation*} \begin{split} (1+ε)\left\{2σ_Cσ_R + σ_C^2 + Cσ_Rσ_*\sqrt{\log(p_1 \wedge p_2)} + Cσ_*^2\log(p_1 \wedge p_2)\right\}, \end{split} \end{equation*} where $σ_C^2 := \max_j \sum_{i=1}^{p_1}σ_{ij}^2$, $σ_R^2 := \max_i \sum_{j=1}^{p_2}σ_{ij}^2$ and $σ_*^2 := \max_{i,j}σ_{ij}^2$. A minimax lower bound is developed that matches this upper bound. Then, we derive the concentration inequalities, moments, and tail bounds for the heteroskedastic Wishart-type matrix under more general distributions, such as sub-Gaussian and heavy-tailed distributions. Next, we consider the cases where $Z$ has homoskedastic columns or rows (i.e., $σ_{ij} \approx σ_i$ or $σ_{ij} \approx σ_j$) and derive the rate-optimal Wishart-type concentration bounds. Finally, we apply the developed tools to identify the sharp signal-to-noise ratio threshold for consistent clustering in the heteroskedastic clustering problem.

preprint2022arXiv

Optimal High-order Tensor SVD via Tensor-Train Orthogonal Iteration

This paper studies a general framework for high-order tensor SVD. We propose a new computationally efficient algorithm, tensor-train orthogonal iteration (TTOI), that aims to estimate the low tensor-train rank structure from the noisy high-order tensor observation. The proposed TTOI consists of initialization via TT-SVD (Oseledets, 2011) and new iterative backward/forward updates. We develop the general upper bound on estimation error for TTOI with the support of several new representation lemmas on tensor matricizations. By developing a matching information-theoretic lower bound, we also prove that TTOI achieves the minimax optimality under the spiked tensor model. The merits of the proposed TTOI are illustrated through applications to estimation and dimension reduction of high-order Markov processes, numerical studies, and a real data example on New York City taxi travel records. The software of the proposed algorithm is available online$^6$.

preprint2022arXiv

Sparse Group Lasso: Optimal Sample Complexity, Convergence Rate, and Statistical Inference

We study sparse group Lasso for high-dimensional double sparse linear regression, where the parameter of interest is simultaneously element-wise and group-wise sparse. This problem is an important instance of the simultaneously structured model -- an actively studied topic in statistics and machine learning. In the noiseless case, matching upper and lower bounds on sample complexity are established for the exact recovery of sparse vectors and for stable estimation of approximately sparse vectors, respectively. In the noisy case, upper and matching minimax lower bounds for estimation error are obtained. We also consider the debiased sparse group Lasso and investigate its asymptotic property for the purpose of statistical inference. Finally, numerical studies are provided to support the theoretical results.

preprint2021arXiv

An Optimal Statistical and Computational Framework for Generalized Tensor Estimation

This paper describes a flexible framework for generalized low-rank tensor estimation problems that includes many important instances arising from applications in computational imaging, genomics, and network analysis. The proposed estimator consists of finding a low-rank tensor fit to the data under generalized parametric models. To overcome the difficulty of non-convexity in these problems, we introduce a unified approach of projected gradient descent that adapts to the underlying low-rank structure. Under mild conditions on the loss function, we establish both an upper bound on statistical error and the linear rate of computational convergence through a general deterministic analysis. Then we further consider a suite of generalized tensor estimation problems, including sub-Gaussian tensor PCA, tensor regression, and Poisson and binomial tensor PCA. We prove that the proposed algorithm achieves the minimax optimal rate of convergence in estimation error. Finally, we demonstrate the superiority of the proposed framework via extensive experiments on both simulated and real data.

preprint2020arXiv

On the Non-asymptotic and Sharp Lower Tail Bounds of Random Variables

The non-asymptotic tail bounds of random variables play crucial roles in probability, statistics, and machine learning. Despite much success in developing upper bounds on tail probability in literature, the lower bounds on tail probabilities are relatively fewer. In this paper, we introduce systematic and user-friendly schemes for developing non-asymptotic lower bounds of tail probabilities. In addition, we develop sharp lower tail bounds for the sum of independent sub-Gaussian and sub-exponential random variables, which match the classic Hoeffding-type and Bernstein-type concentration inequalities, respectively. We also provide non-asymptotic matching upper and lower tail bounds for a suite of distributions, including gamma, beta, (regular, weighted, and noncentral) chi-square, binomial, Poisson, Irwin-Hall, etc. We apply the result to establish the matching upper and lower bounds for extreme value expectation of the sum of independent sub-Gaussian and sub-exponential random variables. A statistical application of signal identification from sparse heterogeneous mixtures is finally considered.

preprint2020arXiv

Open Problem: Average-Case Hardness of Hypergraphic Planted Clique Detection

We note the significance of hypergraphic planted clique (HPC) detection in the investigation of computational hardness for a range of tensor problems. We ask if more evidence for the computational hardness of HPC detection can be developed. In particular, we conjecture if it is possible to establish the equivalence of the computational hardness between HPC and PC detection.