Abstract
We review recent developments and outstanding questions regarding connecting the top-down UV complete physical framework of string theory with the observed physics of the Standard Model and beyond the Standard Model physics, emphasizing the global nonperturbative framework of F-theory and general lessons from UV physics. This paper, prepared for the TF01 conveners of the Snowmass 2022 process, provides a brief synopsis of this important area, focusing on ongoing developments and opportunities.
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