Abstract
The present work proves that the folk-lore of the pathology of non-conservation of probability in quantum anisotropic models is wrong. It is shown in full generality that all operator ordering can lead to a Hamiltonian with a self-adjoint extension as long as it is constructed to be a symmetric operator, thereby making the problem of non-unitarity in context of anisotropic homogeneous model a ghost. Moreover, it is indicated that the self-adjoint extension is not unique and this non-uniqueness is suspected not to be a feature of Anisotropic model only, in the sense that there exists operator orderings such that Hamiltonian for an isotropic homogeneous cosmological model does not have unique self-adjoint extension, albeit for isotropic model, there is a special unique extension associated with quadratic form of Hamiltonian i.e {\it Friedrichs extension}. Details of calculations are carried out for a Bianchi III model.
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