Researcher profile

Zhenhui Li

Zhenhui Li contributes to research discovery and scholarly infrastructure.

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Published work

8 published item(s)

preprint2026arXiv

A Breast Vision Pathology Foundation Model for Real-world Clinical Utility

Pathology foundation models have shown strong retrospective performance, but whether such systems can support clinically relevant use remains unclear. This challenge is particularly important in breast cancer, where pathological assessment serves as the gold standard for diagnosis and guides treatment planning, surgical decision-making and risk stratification across pre-, intra- and post-operative stages. Here we present \textbf{BRAVE}, a breast-adaptive pathology foundation model developed and evaluated using a total resource of 101,638 breast whole-slide images from 32 sources across Asia, Europe and North America. We assessed BRAVE across 34 tasks in 82 cohorts spanning pre-operative biopsy, intra-operative frozen section and post-operative resection, using an evidence chain comprising retrospective benchmarking, clinically challenging scenarios, workflow-oriented clinical impact simulations, prospective observational validation with the thresholds locked in the retrospective cohorts and crossover pathologist-AI interaction studies. Across these settings, BRAVE supported practical roles in the clinical workflow, including safe exclusion of low-risk cases from routine review, AI-assisted second-review rescue of initially missed positives and prioritization of cases for further assessment. In prospective validation across three centres, BRAVE excluded 76.9% of negative biopsy cases (NPV 0.953) and 70.1% of negative frozen-section cases (NPV 0.973), and triaged 78.8% of post-operative subtyping cases as high-confidence clear-cut cases (NPV 1.000). In reader studies, AI assistance improved balanced accuracy from 88.5% to 95.1% (OR 3.14, P<0.001), with better efficiency, confidence and inter-rater agreement. BRAVE-derived scores also independently predicted disease-free survival (adjusted HR 4.79, P<0.001) and overall survival (adjusted HR 8.14, P<0.001).

preprint2022arXiv

Objective-aware Traffic Simulation via Inverse Reinforcement Learning

Traffic simulators act as an essential component in the operating and planning of transportation systems. Conventional traffic simulators usually employ a calibrated physical car-following model to describe vehicles&#39; behaviors and their interactions with traffic environment. However, there is no universal physical model that can accurately predict the pattern of vehicle&#39;s behaviors in different situations. A fixed physical model tends to be less effective in a complicated environment given the non-stationary nature of traffic dynamics. In this paper, we formulate traffic simulation as an inverse reinforcement learning problem, and propose a parameter sharing adversarial inverse reinforcement learning model for dynamics-robust simulation learning. Our proposed model is able to imitate a vehicle&#39;s trajectories in the real world while simultaneously recovering the reward function that reveals the vehicle&#39;s true objective which is invariant to different dynamics. Extensive experiments on synthetic and real-world datasets show the superior performance of our approach compared to state-of-the-art methods and its robustness to variant dynamics of traffic.

preprint2020arXiv

A Probabilistic Simulator of Spatial Demand for Product Allocation

Connecting consumers with relevant products is a very important problem in both online and offline commerce. In physical retail, product placement is an effective way to connect consumers with products. However, selecting product locations within a store can be a tedious process. Moreover, learning important spatial patterns in offline retail is challenging due to the scarcity of data and the high cost of exploration and experimentation in the physical world. To address these challenges, we propose a stochastic model of spatial demand in physical retail. We show that the proposed model is more predictive of demand than existing baselines. We also perform a preliminary study into different automation techniques and show that an optimal product allocation policy can be learned through Deep Q-Learning.

preprint2020arXiv

A Survey on Traffic Signal Control Methods

Traffic signal control is an important and challenging real-world problem, which aims to minimize the travel time of vehicles by coordinating their movements at the road intersections. Current traffic signal control systems in use still rely heavily on oversimplified information and rule-based methods, although we now have richer data, more computing power and advanced methods to drive the development of intelligent transportation. With the growing interest in intelligent transportation using machine learning methods like reinforcement learning, this survey covers the widely acknowledged transportation approaches and a comprehensive list of recent literature on reinforcement for traffic signal control. We hope this survey can foster interdisciplinary research on this important topic.

preprint2020arXiv

Automated Relational Meta-learning

In order to efficiently learn with small amount of data on new tasks, meta-learning transfers knowledge learned from previous tasks to the new ones. However, a critical challenge in meta-learning is the task heterogeneity which cannot be well handled by traditional globally shared meta-learning methods. In addition, current task-specific meta-learning methods may either suffer from hand-crafted structure design or lack the capability to capture complex relations between tasks. In this paper, motivated by the way of knowledge organization in knowledge bases, we propose an automated relational meta-learning (ARML) framework that automatically extracts the cross-task relations and constructs the meta-knowledge graph. When a new task arrives, it can quickly find the most relevant structure and tailor the learned structure knowledge to the meta-learner. As a result, the proposed framework not only addresses the challenge of task heterogeneity by a learned meta-knowledge graph, but also increases the model interpretability. We conduct extensive experiments on 2D toy regression and few-shot image classification and the results demonstrate the superiority of ARML over state-of-the-art baselines.

preprint2020arXiv

Automatic Historical Feature Generation through Tree-based Method in Ads Prediction

Historical features are important in ads click-through rate (CTR) prediction, because they account for past engagements between users and ads. In this paper, we study how to efficiently construct historical features through counting features. The key challenge of such problem lies in how to automatically identify counting keys. We propose a tree-based method for counting key selection. The intuition is that a decision tree naturally provides various combinations of features, which could be used as counting key candidate. In order to select personalized counting features, we train one decision tree model per user, and the counting keys are selected across different users with a frequency-based importance measure. To validate the effectiveness of proposed solution, we conduct large scale experiments on Twitter video advertising data. In both online learning and offline training settings, the automatically identified counting features outperform the manually curated counting features.

preprint2020arXiv

Graph Few-shot Learning via Knowledge Transfer

Towards the challenging problem of semi-supervised node classification, there have been extensive studies. As a frontier, Graph Neural Networks (GNNs) have aroused great interest recently, which update the representation of each node by aggregating information of its neighbors. However, most GNNs have shallow layers with a limited receptive field and may not achieve satisfactory performance especially when the number of labeled nodes is quite small. To address this challenge, we innovatively propose a graph few-shot learning (GFL) algorithm that incorporates prior knowledge learned from auxiliary graphs to improve classification accuracy on the target graph. Specifically, a transferable metric space characterized by a node embedding and a graph-specific prototype embedding function is shared between auxiliary graphs and the target, facilitating the transfer of structural knowledge. Extensive experiments and ablation studies on four real-world graph datasets demonstrate the effectiveness of our proposed model.

preprint2020arXiv

Learning from Multiple Cities: A Meta-Learning Approach for Spatial-Temporal Prediction

Spatial-temporal prediction is a fundamental problem for constructing smart city, which is useful for tasks such as traffic control, taxi dispatching, and environmental policy making. Due to data collection mechanism, it is common to see data collection with unbalanced spatial distributions. For example, some cities may release taxi data for multiple years while others only release a few days of data; some regions may have constant water quality data monitored by sensors whereas some regions only have a small collection of water samples. In this paper, we tackle the problem of spatial-temporal prediction for the cities with only a short period of data collection. We aim to utilize the long-period data from other cities via transfer learning. Different from previous studies that transfer knowledge from one single source city to a target city, we are the first to leverage information from multiple cities to increase the stability of transfer. Specifically, our proposed model is designed as a spatial-temporal network with a meta-learning paradigm. The meta-learning paradigm learns a well-generalized initialization of the spatial-temporal network, which can be effectively adapted to target cities. In addition, a pattern-based spatial-temporal memory is designed to distill long-term temporal information (i.e., periodicity). We conduct extensive experiments on two tasks: traffic (taxi and bike) prediction and water quality prediction. The experiments demonstrate the effectiveness of our proposed model over several competitive baseline models.