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Yue Sun

Yue Sun contributes to research discovery and scholarly infrastructure.

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Published work

6 published item(s)

preprint2026arXiv

A Review of Urban Resilience Frameworks: Transferring Knowledge to Enhance Pandemic Resilience

Urbanization is rapidly increasing, with urban populations expected to grow significantly by 2050, particularly in developing regions. This expansion brings challenges related to chronic stresses and acute shocks, such as the COVID-19 pandemic, which has underscored the critical role of urban form in a city's capacity to manage public health crises. Despite the heightened interest in urban resilience, research examining the relationship between urban morphology and pandemic resilience remains limited, often focusing solely on density and its effect on disease transmission. This work aims to address this gap by evaluating existing frameworks that analyze the relationship between urban resilience and urban form. By critically reviewing these frameworks, with a particular emphasis on theoretical and quantitative approaches, this study seeks to transfer the knowledge gained to better understand the relationship between pandemic resilience and urban morphology. The work also links theoretical ideas with quantitative frameworks, offering a cohesive analysis. The anticipated novelty of this study lies in its comprehensive assessment of urban resilience frameworks and the identification of the current gaps in integrating resilience to pandemic thinking into urban planning and design. The goal is not only to enhance the understanding of urban resilience but also to offer practical guidance for developing more adaptive and effective frameworks for assessing resilience to pandemics in urban environments, thereby preparing cities to better withstand and recover from future crises.

preprint2026arXiv

Conditional Diffusion Model with Anatomical-Dose Dual Constraints for End-to-End Multi-Tumor Dose Prediction

Radiotherapy treatment planning often relies on time-consuming, trial-and-error adjustments that heavily depend on the expertise of specialists, while existing deep learning methods face limitations in generalization, prediction accuracy, and clinical applicability. To tackle these challenges, we propose ADDiff-Dose, an Anatomical-Dose Dual Constraints Conditional Diffusion Model for end-to-end multi-tumor dose prediction. The model employs LightweightVAE3D to compress high-dimensional CT data and integrates multimodal inputs, including target and organ-at-risk (OAR) masks and beam parameters, within a progressive noise addition and denoising framework. It incorporates conditional features via a multi-head attention mechanism and utilizes a composite loss function combining MSE, conditional terms, and KL divergence to ensure both dosimetric accuracy and compliance with clinical constraints. Evaluation on a large-scale public dataset (2,877 cases) and three external institutional cohorts (450 cases in total) demonstrates that ADDiff-Dose significantly outperforms traditional baselines, achieving an MAE of 0.101-0.154 (compared to 0.316 for UNet and 0.169 for GAN models), a DICE coefficient of 0.927 (a 6.8% improvement), and limiting spinal cord maximum dose error to within 0.1 Gy. The average plan generation time per case is reduced to 22 seconds. Ablation studies confirm that the structural encoder enhances compliance with clinical dose constraints by 28.5%. To our knowledge, this is the first study to introduce a conditional diffusion model framework for radiotherapy dose prediction, offering a generalizable and efficient solution for automated treatment planning across diverse tumor sites, with the potential to substantially reduce planning time and improve clinical workflow efficiency.

preprint2026arXiv

Diagnostic Performance of Universal-Learning Ultrasound AI Across Multiple Organs and Tasks: the UUSIC25 Challenge

IMPORTANCE: Modern ultrasound systems are universal diagnostic tools capable of imaging the entire body. However, current AI solutions remain fragmented into single-task tools. This critical gap between hardware versatility and software specificity limits workflow integration and clinical utility. OBJECTIVE: To evaluate the diagnostic accuracy, versatility, and efficiency of single general-purpose deep learning models for multi-organ classification and segmentation. DESIGN: The Universal UltraSound Image Challenge 2025 (UUSIC25) involved developing algorithms on 11,644 images aggregated from 12 sources (9 public, 3 private). Evaluation used an independent, multi-center private test set of 2,479 images, including data from a center completely unseen during training to assess generalization. OUTCOMES: Diagnostic performance (Dice Similarity Coefficient [DSC]; Area Under the Receiver Operating Characteristic Curve [AUC]) and computational efficiency (inference time, GPU memory). RESULTS: Of 15 valid algorithms, the top model (SMART) achieved a macro-averaged DSC of 0.854 across 5 segmentation tasks and AUC of 0.766 for binary classification. Models demonstrated high capability in anatomical segmentation (e.g., fetal head DSC: 0.942) but variability in complex diagnostic tasks subject to domain shift. Specifically, in breast cancer molecular subtyping, the top model's performance dropped from an AUC of 0.571 (internal) to 0.508 (unseen external center), highlighting the challenge of generalization. CONCLUSIONS: General-purpose AI models can achieve high accuracy and efficiency across multiple tasks using a single architecture. However, significant performance degradation on unseen data suggests domain generalization is critical for future clinical deployment.

preprint2026arXiv

MemFine: Memory-Aware Fine-Grained Scheduling for MoE Training

The training of large-scale Mixture of Experts (MoE) models faces a critical memory bottleneck due to severe load imbalance caused by dynamic token routing. This imbalance leads to memory overflow on GPUs with limited capacity, constraining model scalability. Existing load balancing methods, which cap expert capacity, compromise model accuracy and fail on memory-constrained hardware. To address this, we propose MemFine, a memory-aware fine-grained scheduling framework for MoE training. MemFine decomposes the token distribution and expert computation into manageable chunks and employs a chunked recomputation strategy, dynamically optimized through a theoretical memory model to balance memory efficiency and throughput. Experiments demonstrate that MemFine reduces activation memory by 48.03% and improves throughput by 4.42% compared to full recomputation-based baselines, enabling stable large-scale MoE training on memory-limited GPUs.

preprint2026arXiv

MoGen: A Unified Collaborative Framework for Controllable Multi-Object Image Generation

Existing multi-object image generation methods face difficulties in achieving precise alignment between localized image generation regions and their corresponding semantics based on language descriptions, frequently resulting in inconsistent object quantities and attribute aliasing. To mitigate this limitation, mainstream approaches typically rely on external control signals to explicitly constrain the spatial layout, local semantic and visual attributes of images. However, this strong dependency makes the input format rigid, rendering it incompatible with the heterogeneous resource conditions of users and diverse constraint requirements. To address these challenges, we propose MoGen, a user-friendly multi-object image generation method. First, we design a Regional Semantic Anchor (RSA) module that precisely anchors phrase units in language descriptions to their corresponding image regions during the generation process, enabling text-to-image generation that follows quantity specifications for multiple objects. Building upon this foundation, we further introduce an Adaptive Multi-modal Guidance (AMG) module, which adaptively parses and integrates various combinations of multi-source control signals to formulate corresponding structured intent. This intent subsequently guides selective constraints on scene layouts and object attributes, achieving dynamic fine-grained control. Experimental results demonstrate that MoGen significantly outperforms existing methods in generation quality, quantity consistency, and fine-grained control, while exhibiting superior accessibility and control flexibility. Code is available at: https://github.com/Tear-kitty/MoGen/tree/master.

preprint2026arXiv

Semantic-Enriched Latent Visual Reasoning

Multimodal latent-space reasoning aims to replace explicit thinking with images by performing visual reasoning directly in a compact latent space. However, existing approaches largely rely on visual supervision and produce latent representations that lack sufficient semantic richness, limiting their ability to support diverse region-level reasoning tasks. In this work, we introduce Semantic-Enriched Latent Visual Reasoning (SLVR), a two-stage learning framework that enriches latent representations with attribute-level visual semantics and aligns them with diverse reasoning objectives. In the first stage, SLVR learns semantically enriched region-centric latents under fine-grained attribute supervision. In the second stage, we design Multi-query Group Relative Policy Optimization (M-GRPO) to align latent representations across multiple queries grounded in the same region. To support this framework, we construct SLV-Set, comprising approximately 400K region-level attribute annotations and 800K multi-query question answering samples, and introduce SV-QA, a benchmark that evaluates latent reasoning under semantic variation. Experiments demonstrate that SLVR improves the robustness and semantic consistency of latent visual reasoning compared to existing baselines.