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Yingxue Xu

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Computer Vision eess.IV Machine Learning

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preprint2026arXiv

A Breast Vision Pathology Foundation Model for Real-world Clinical Utility

Pathology foundation models have shown strong retrospective performance, but whether such systems can support clinically relevant use remains unclear. This challenge is particularly important in breast cancer, where pathological assessment serves as the gold standard for diagnosis and guides treatment planning, surgical decision-making and risk stratification across pre-, intra- and post-operative stages. Here we present \textbf{BRAVE}, a breast-adaptive pathology foundation model developed and evaluated using a total resource of 101,638 breast whole-slide images from 32 sources across Asia, Europe and North America. We assessed BRAVE across 34 tasks in 82 cohorts spanning pre-operative biopsy, intra-operative frozen section and post-operative resection, using an evidence chain comprising retrospective benchmarking, clinically challenging scenarios, workflow-oriented clinical impact simulations, prospective observational validation with the thresholds locked in the retrospective cohorts and crossover pathologist-AI interaction studies. Across these settings, BRAVE supported practical roles in the clinical workflow, including safe exclusion of low-risk cases from routine review, AI-assisted second-review rescue of initially missed positives and prioritization of cases for further assessment. In prospective validation across three centres, BRAVE excluded 76.9% of negative biopsy cases (NPV 0.953) and 70.1% of negative frozen-section cases (NPV 0.973), and triaged 78.8% of post-operative subtyping cases as high-confidence clear-cut cases (NPV 1.000). In reader studies, AI assistance improved balanced accuracy from 88.5% to 95.1% (OR 3.14, P<0.001), with better efficiency, confidence and inter-rater agreement. BRAVE-derived scores also independently predicted disease-free survival (adjusted HR 4.79, P<0.001) and overall survival (adjusted HR 8.14, P<0.001).

preprint2021arXiv

Graph-based Visual-Semantic Entanglement Network for Zero-shot Image Recognition

Zero-shot learning uses semantic attributes to connect the search space of unseen objects. In recent years, although the deep convolutional network brings powerful visual modeling capabilities to the ZSL task, its visual features have severe pattern inertia and lack of representation of semantic relationships, which leads to severe bias and ambiguity. In response to this, we propose the Graph-based Visual-Semantic Entanglement Network to conduct graph modeling of visual features, which is mapped to semantic attributes by using a knowledge graph, it contains several novel designs: 1. it establishes a multi-path entangled network with the convolutional neural network (CNN) and the graph convolutional network (GCN), which input the visual features from CNN to GCN to model the implicit semantic relations, then GCN feedback the graph modeled information to CNN features; 2. it uses attribute word vectors as the target for the graph semantic modeling of GCN, which forms a self-consistent regression for graph modeling and supervise GCN to learn more personalized attribute relations; 3. it fuses and supplements the hierarchical visual-semantic features refined by graph modeling into visual embedding. Our method outperforms state-of-the-art approaches on multiple representative ZSL datasets: AwA2, CUB, and SUN by promoting the semantic linkage modelling of visual features.

preprint2020arXiv

Multiple Attentional Pyramid Networks for Chinese Herbal Recognition

Chinese herbs play a critical role in Traditional Chinese Medicine. Due to different recognition granularity, they can be recognized accurately only by professionals with much experience. It is expected that they can be recognized automatically using new techniques like machine learning. However, there is no Chinese herbal image dataset available. Simultaneously, there is no machine learning method which can deal with Chinese herbal image recognition well. Therefore, this paper begins with building a new standard Chinese-Herbs dataset. Subsequently, a new Attentional Pyramid Networks (APN) for Chinese herbal recognition is proposed, where both novel competitive attention and spatial collaborative attention are proposed and then applied. APN can adaptively model Chinese herbal images with different feature scales. Finally, a new framework for Chinese herbal recognition is proposed as a new application of APN. Experiments are conducted on our constructed dataset and validate the effectiveness of our methods.