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Researcher profile

Shaoliang Peng

Shaoliang Peng contributes to research discovery and scholarly infrastructure.

ResearcherAffiliation not importedOpen to collaborate
Computer Visioneess.IVMachine LearningArtificial IntelligenceQuantitative Methods

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Published work

4 published item(s)

preprint2026arXiv

Diffusion Attention Expert Model for Predicting and Semi-automatic Localizing STAS in Lung Cancer Histopathological Images

Accurate intraoperative and postoperative diagnosis of spread through air spaces (STAS) is essential for guiding surgical decisions and postoperative management in lung cancer. However, histopathological assessment is labor-intensive and is prone to missed or incorrect diagnoses. We propose a Diffusion Attention Expert Model (DAEM) to detect STAS in frozen sections (FSs) and paraffin sections (PSs). Its diffusion attention expert module leverages full attention aggregation to learn multi-scale features from histopathological images, while a dual-branch architecture strengthens multi-scale feature representation. On an internal dataset, DAEM achieves AUCs of 0.8946 for FSs and 0.9112 for PSs. Validation on external multi-center datasets from eight institutions demonstrates strong generalizability and interpretability. Using tumor microenvironment (TME) features in PSs, we further enable semi-automatic measurement of STAS location and its distance from the primary tumor. Several quantitative TME metrics are identified as potential biomarkers for STAS, including micropapillary-type STAS. Overall, DAEM offers a clinically actionable framework for STAS assessment by enabling accurate and interpretable detection on FSs and PSs, supporting postoperative risk stratification through quantitative TME-based analysis.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

A review of machine learning approaches, challenges and prospects for computational tumor pathology

Computational pathology is part of precision oncology medicine. The integration of high-throughput data including genomics, transcriptomics, proteomics, metabolomics, pathomics, and radiomics into clinical practice improves cancer treatment plans, treatment cycles, and cure rates, and helps doctors open up innovative approaches to patient prognosis. In the past decade, rapid advances in artificial intelligence, chip design and manufacturing, and mobile computing have facilitated research in computational pathology and have the potential to provide better-integrated solutions for whole-slide images, multi-omics data, and clinical informatics. However, tumor computational pathology now brings some challenges to the application of tumour screening, diagnosis and prognosis in terms of data integration, hardware processing, network sharing bandwidth and machine learning technology. This review investigates image preprocessing methods in computational pathology from a pathological and technical perspective, machine learning-based methods, and applications of computational pathology in breast, colon, prostate, lung, and various tumour disease scenarios. Finally, the challenges and prospects of machine learning in computational pathology applications are discussed.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

FEDI: Few-shot learning based on Earth Mover's Distance algorithm combined with deep residual network to identify diabetic retinopathy

Diabetic retinopathy(DR) is the main cause of blindness in diabetic patients. However, DR can easily delay the occurrence of blindness through the diagnosis of the fundus. In view of the reality, it is difficult to collect a large amount of diabetic retina data in clinical practice. This paper proposes a few-shot learning model of a deep residual network based on Earth Mover's Distance algorithm to assist in diagnosing DR. We build training and validation classification tasks for few-shot learning based on 39 categories of 1000 sample data, train deep residual networks, and obtain experience maximization pre-training models. Based on the weights of the pre-trained model, the Earth Mover's Distance algorithm calculates the distance between the images, obtains the similarity between the images, and changes the model's parameters to improve the accuracy of the training model. Finally, the experimental construction of the small sample classification task of the test set to optimize the model further, and finally, an accuracy of 93.5667% on the 3way10shot task of the diabetic retina test set. For the experimental code and results, please refer to: https://github.com/panliangrui/few-shot-learning-funds.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Noise-reducing attention cross fusion learning transformer for histological image classification of osteosarcoma

The degree of malignancy of osteosarcoma and its tendency to metastasize/spread mainly depend on the pathological grade (determined by observing the morphology of the tumor under a microscope). The purpose of this study is to use artificial intelligence to classify osteosarcoma histological images and to assess tumor survival and necrosis, which will help doctors reduce their workload, improve the accuracy of osteosarcoma cancer detection, and make a better prognosis for patients. The study proposes a typical transformer image classification framework by integrating noise reduction convolutional autoencoder and feature cross fusion learning (NRCA-FCFL) to classify osteosarcoma histological images. Noise reduction convolutional autoencoder could well denoise histological images of osteosarcoma, resulting in more pure images for osteosarcoma classification. Moreover, we introduce feature cross fusion learning, which integrates two scale image patches, to sufficiently explore their interactions by using additional classification tokens. As a result, a refined fusion feature is generated, which is fed to the residual neural network for label predictions. We conduct extensive experiments to evaluate the performance of the proposed approach. The experimental results demonstrate that our method outperforms the traditional and deep learning approaches on various evaluation metrics, with an accuracy of 99.17% to support osteosarcoma diagnosis.

0 citations0 reviewsNo code linkedOpen access