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Researcher profile

Ron Alterovitz

Ron Alterovitz contributes to research discovery and scholarly infrastructure.

ResearcherAffiliation not importedOpen to collaborate
RoboticsArtificial IntelligenceComputation and LanguageComputer Visioneess.SPeess.SYMachine LearningSystems and Control

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Published work

7 published item(s)

preprint2026arXiv

Contact-aware Path Planning for Autonomous Neuroendovascular Navigation

We propose a deterministic and time-efficient contact-aware path planner for neurovascular navigation. The algorithm leverages information from pre- and intra-operative images of the vessels to navigate pre-bent passive tools, by intelligently predicting and exploiting interactions with the anatomy. A kinematic model is derived and employed by the sampling-based planner for tree expansion that utilizes simplified motion primitives. This approach enables fast computation of the feasible path, with negligible loss in accuracy, as demonstrated in diverse and representative anatomies of the vessels. In these anatomical demonstrators, the algorithm shows a 100% convergence rate within 22.8s in the worst case, with sub-millimeter tracking errors (less than 0.64 mm), and is found effective on anatomical phantoms representative of around 94% of patients.

0 citations0 reviewsNo code linkedOpen access
preprint2026arXiv

From Prompts to Protocols: An AI Agent for Laboratory Automation

Automating science laboratories enables faster, safer, more accurate, and more reproducible execution of protocols, accelerating the discovery and testing of new materials, drugs, and more. However, setting up and running autonomous labs requires coordinating numerous instruments and robots, forcing scientists to write code, manage configuration files, and navigate complex software infrastructure. We present an AI agent architecture that integrates large language models with laboratory orchestration, enabling scientists to interactively create and monitor automated lab protocols using natural language. Integrated into the Experiment Orchestration System (EOS), the AI agent operates under an agentic loop with automated validation and error correction, and supports the complete experimental lifecycle: creating protocols, running and monitoring both protocols and closed-loop optimization campaigns, and analyzing results. A visual graph editor renders protocols as interactive node-based diagrams synchronized with the AI agent's protocol representation, enabling seamless alternation between AI-assisted and manual protocol construction. Evaluated on three simulated automated labs spanning chemistry, biology, and materials science, the AI agent achieves a 97% first-attempt protocol generation success rate and an order of magnitude reduction in required interface actions.

0 citations0 reviewsNo code linkedOpen access
preprint2026arXiv

Stop Holding Your Breath: CT-Informed Gaussian Splatting for Dynamic Bronchoscopy

Bronchoscopic navigation relies on registering endoscopic video to a preoperative CT scan, but respiratory motion deforms the airway by 5-20 mm, creating CT-to-body divergence that limits localization accuracy. In practice, this is mitigated through breath-hold protocols, which attempt to match the intraoperative anatomy to a static CT, but are difficult to reproduce and disrupt clinical workflow. We propose to eliminate the need for breath-hold protocols by leveraging patient-specific respiratory modeling. Paired inhale-exhale CT scans, already acquired for planning, implicitly define the patient-specific deformation space of the breathing airway. By registering these scans, we reduce respiratory motion to a single scalar breathing phase per frame, constraining all reconstructions to anatomically observed configurations. We embed this representation within a mesh-anchored Gaussian splatting framework, where a lightweight estimator infers breathing phase directly from endoscopic RGB, enabling continuous, deformation-aware reconstruction throughout the respiratory cycle without breath-holds or external sensing. To enable quantitative evaluation, we introduce RESPIRE, a physically grounded bronchoscopy simulation pipeline with per-frame ground truth for geometry, pose, breathing phase, and deformation. Experiments on RESPIRE show that our approach achieves geometrically faithful reconstruction, over 20x faster training, and 1.22 mm target localization accuracy (within the 3mm clinically relevant tolerances) outperforming unconstrained single-CT baselines. Please check out our website for additional visuals: https://asdunnbe.github.io/RESPIRE/

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Resolution-Optimal Motion Planning for Steerable Needles

Medical steerable needles can follow 3D curvilinear trajectories inside body tissue, enabling them to move around critical anatomical structures and precisely reach clinically significant targets in a minimally invasive way. Automating needle steering, with motion planning as a key component, has the potential to maximize the accuracy, precision, speed, and safety of steerable needle procedures. In this paper, we introduce the first resolution-optimal motion planner for steerable needles that offers excellent practical performance in terms of runtime while simultaneously providing strong theoretical guarantees on completeness and the global optimality of the motion plan in finite time. Compared to state-of-the-art steerable needle motion planners, simulation experiments on realistic scenarios of lung biopsy demonstrate that our proposed planner is faster in generating higher-quality plans while incorporating clinically relevant cost functions. This indicates that the theoretical guarantees of the proposed planner have a practical impact on the motion plan quality, which is valuable for computing motion plans that minimize patient trauma.

0 citations0 reviewsNo code linkedOpen access
preprint2021arXiv

A Recurrent Neural Network Approach to Roll Estimation for Needle Steering

Steerable needles are a promising technology for delivering targeted therapies in the body in a minimally-invasive fashion, as they can curve around anatomical obstacles and hone in on anatomical targets. In order to accurately steer them, controllers must have full knowledge of the needle tip's orientation. However, current sensors either do not provide full orientation information or interfere with the needle's ability to deliver therapy. Further, torsional dynamics can vary and depend on many parameters making steerable needles difficult to accurately model, limiting the effectiveness of traditional observer methods. To overcome these limitations, we propose a model-free, learned-method that leverages LSTM neural networks to estimate the needle tip's orientation online. We validate our method by integrating it into a sliding-mode controller and steering the needle to targets in gelatin and ex vivo ovine brain tissue. We compare our method's performance against an Extended Kalman Filter, a model-based observer, achieving significantly lower targeting errors.

0 citations0 reviewsNo code linkedOpen access
preprint2021arXiv

Robust Navigation of a Soft Growing Robot by Exploiting Contact with the Environment

Navigation and motion control of a robot to a destination are tasks that have historically been performed with the assumption that contact with the environment is harmful. This makes sense for rigid-bodied robots where obstacle collisions are fundamentally dangerous. However, because many soft robots have bodies that are low-inertia and compliant, obstacle contact is inherently safe. As a result, constraining paths of the robot to not interact with the environment is not necessary and may be limiting. In this paper, we mathematically formalize interactions of a soft growing robot with a planar environment in an empirical kinematic model. Using this interaction model, we develop a method to plan paths for the robot to a destination. Rather than avoiding contact with the environment, the planner exploits obstacle contact when beneficial for navigation. We find that a planner that takes into account and capitalizes on environmental contact produces paths that are more robust to uncertainty than a planner that avoids all obstacle contact.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Enabling Robots to Understand Incomplete Natural Language Instructions Using Commonsense Reasoning

Enabling robots to understand instructions provided via spoken natural language would facilitate interaction between robots and people in a variety of settings in homes and workplaces. However, natural language instructions are often missing information that would be obvious to a human based on environmental context and common sense, and hence does not need to be explicitly stated. In this paper, we introduce Language-Model-based Commonsense Reasoning (LMCR), a new method which enables a robot to listen to a natural language instruction from a human, observe the environment around it, and automatically fill in information missing from the instruction using environmental context and a new commonsense reasoning approach. Our approach first converts an instruction provided as unconstrained natural language into a form that a robot can understand by parsing it into verb frames. Our approach then fills in missing information in the instruction by observing objects in its vicinity and leveraging commonsense reasoning. To learn commonsense reasoning automatically, our approach distills knowledge from large unstructured textual corpora by training a language model. Our results show the feasibility of a robot learning commonsense knowledge automatically from web-based textual corpora, and the power of learned commonsense reasoning models in enabling a robot to autonomously perform tasks based on incomplete natural language instructions.

0 citations0 reviewsNo code linkedOpen access