Researcher profile

Mohamed Elsayed

Mohamed Elsayed contributes to research discovery and scholarly infrastructure.

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Published work

2 published item(s)

preprint2026arXiv

Extending Differential Temporal Difference Methods for Episodic Problems

Differential temporal difference (TD) methods are value-based reinforcement learning algorithms that have been proposed for infinite-horizon problems. They rely on reward centering, where each reward is centered by the average reward. This keeps the return bounded and removes a value function's state-independent offset. However, reward centering can alter the optimal policy in episodic problems, limiting its applicability. Motivated by recent works that emphasize the role of normalization in streaming deep reinforcement learning, we study reward centering in episodic problems and propose a generalization of differential TD. We prove that this generalization maintains the ordering of policies in the presence of termination, and thus extends differential TD to episodic problems. We show equivalence with a form of linear TD, thereby inheriting theoretical guarantees that have been shown for those algorithms. We then extend several streaming reinforcement learning algorithms to their differential counterparts. Across a range of base algorithms and environments, we empirically validate that reward centering can improve sample efficiency in episodic problems.

preprint2021arXiv

Autonomous object harvesting using synchronized optoelectronic microrobots

Optoelectronic tweezer-driven microrobots (OETdMs) are a versatile micromanipulation technology based on the use of light induced dielectrophoresis to move small dielectric structures (microrobots) across a photoconductive substrate. The microrobots in turn can be used to exert forces on secondary objects and carry out a wide range of micromanipulation operations, including collecting, transporting and depositing microscopic cargos. In contrast to alternative (direct) micromanipulation techniques, OETdMs are relatively gentle, making them particularly well suited to interacting with sensitive objects such as biological cells. However, at present such systems are used exclusively under manual control by a human operator. This limits the capacity for simultaneous control of multiple microrobots, reducing both experimental throughput and the possibility of cooperative multi-robot operations. In this article, we describe an approach to automated targeting and path planning to enable open-loop control of multiple microrobots. We demonstrate the performance of the method in practice, using microrobots to simultaneously collect, transport and deposit silica microspheres. Using computational simulations based on real microscopic image data, we investigate the capacity of microrobots to collect target cells from within a dissociated tissue culture. Our results indicate the feasibility of using OETdMs to autonomously carry out micromanipulation tasks within complex, unstructured environments.