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Mario Pezzella

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2 published item(s)

preprint2026arXiv

EPITIME: A Computational Framework for Integral Epidemic Models with Structure-Preserving Discretizations

We present EPITIME (EPidemic Integral models TIMe profile Explorer), a computational framework for the simulation of two classes of integral epidemic models: an age of infection model and an information dependent behavioural model. The framework combines structure preserving Non-Standard Finite Difference discretizations with modular implementations in MATLAB and Python, together with routines for parameter handling, input validation, performance assessment, and graphical interaction. The proposed methods preserve key qualitative properties of the continuous problems, including positivity, boundedness, invariant regions, and correct long term behaviour, independently of the time step. We outline the numerical schemes for both model classes and their main analytical properties, including first order convergence. We then describe the software architecture and illustrate its use through numerical experiments on asymptotic behaviour, inverse reconstruction of an infectivity kernel from COVID 19 incidence data, and behavioural dynamics under different memory kernels. Overall, EPITIME provides a reliable and accessible computational environment for the numerical study of renewal epidemic models.

preprint2025arXiv

Modified Patankar Semi-Lagrangian Scheme for the Optimal Control of Production-Destruction systems

In this manuscript, we present a comprehensive theoretical and numerical framework for the control of production-destruction differential systems. The general finite horizon optimal control problem is formulated and addressed through the dynamic programming approach. We develop a parallel in space conservative scheme for the corresponding backward-in-time Hamilton-Jacobi-Bellman equation. Furthermore, we provide a suitable reconstruction algorithm for optimal controls and trajectories. The application to two case studies, specifically enzyme catalyzed biochemical reactions and infectious diseases, highlights the advantages of the proposed methodology over classical semi-Lagrangian discretizations.