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Bruno Buonomo

Bruno Buonomo contributes to research discovery and scholarly infrastructure.

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Published work

2 published item(s)

preprint2026arXiv

EPITIME: A Computational Framework for Integral Epidemic Models with Structure-Preserving Discretizations

We present EPITIME (EPidemic Integral models TIMe profile Explorer), a computational framework for the simulation of two classes of integral epidemic models: an age of infection model and an information dependent behavioural model. The framework combines structure preserving Non-Standard Finite Difference discretizations with modular implementations in MATLAB and Python, together with routines for parameter handling, input validation, performance assessment, and graphical interaction. The proposed methods preserve key qualitative properties of the continuous problems, including positivity, boundedness, invariant regions, and correct long term behaviour, independently of the time step. We outline the numerical schemes for both model classes and their main analytical properties, including first order convergence. We then describe the software architecture and illustrate its use through numerical experiments on asymptotic behaviour, inverse reconstruction of an infectivity kernel from COVID 19 incidence data, and behavioural dynamics under different memory kernels. Overall, EPITIME provides a reliable and accessible computational environment for the numerical study of renewal epidemic models.

preprint2020arXiv

Modeling the effects of information-dependent vaccination behavior on meningitis transmission

We propose a mathematical model to investigate the effects of information-dependent vaccination behavior on meningitis transmission. The information is represented by means of information index as early proposed in (d'Onofrio et al., Theor. pop. biol., 2007). We perform a qualitative analysis based on stability theory, focusing to the global stability of the disease free equilibrium (DFE) and the related transcritical bifurcation taking place at the threshold for the DFE. Finally, we assess the role of epidemiological and information parameters in the model dynamics through numerical simulations. Our simulations suggests that the impact of the human behavior critically depend on the average information delay. For example, it can induce recurrent epidemics, provided that transfer rate from the carrier to the infectious state is over a threshold. Otherwise, the endemic equilibrium is (at least) locally stable.