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Kaiyuan Gao

Kaiyuan Gao contributes to research discovery and scholarly infrastructure.

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Computer Vision Machine Learning Artificial Intelligence Biomolecules Computation and Language

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preprint2026arXiv

Qwen-Image-2.0 Technical Report

We present Qwen-Image-2.0, an omni-capable image generation foundation model that unifies high-fidelity generation and precise image editing within a single framework. Despite recent progress, existing models still struggle with ultra-long text rendering, multilingual typography, high-resolution photorealism, robust instruction following, and efficient deployment, especially in text-rich and compositionally complex scenarios. Qwen-Image-2.0 addresses these challenges by coupling Qwen3-VL as the condition encoder with a Multimodal Diffusion Transformer for joint condition-target modeling, supported by large-scale data curation and a customized multi-stage training pipeline. This enables strong multimodal understanding while preserving flexible generation and editing capabilities. The model supports instructions of up to 1K tokens for generating text-rich content such as slides, posters, infographics, and comics, while significantly improving multilingual text fidelity and typography. It also enhances photorealistic generation with richer details, more realistic textures, and coherent lighting, and follows complex prompts more reliably across diverse styles. Extensive human evaluations show that Qwen-Image-2.0 substantially outperforms previous Qwen-Image models in both generation and editing, marking a step toward more general, reliable, and practical image generation foundation models.

preprint2026arXiv

Qwen-Image-VAE-2.0 Technical Report

We present Qwen-Image-VAE-2.0, a suite of high-compression Variational Autoencoders (VAEs) that achieve significant advances in both reconstruction fidelity and diffusability. To address the reconstruction bottlenecks of high compression, we adopt an improved architecture featuring Global Skip Connections (GSC) and expanded latent channels. Moreover, we scale training to billions of images and incorporate a synthetic rendering engine to improve performance in text-rich scenarios. To tackle the convergence challenges of high-dimensional latent space, we implement an enhanced semantic alignment strategy to make the latent space highly amenable to diffusion modeling. To optimize computational efficiency, we leverage an asymmetric and attention-free encoder-decoder backbone to minimize encoding overhead. We present a comprehensive evaluation of Qwen-Image-VAE-2.0 on public reconstruction benchmarks. To evaluate performance in text-rich scenarios, we propose OmniDoc-TokenBench, a new benchmark comprising a diverse collection of real-world documents coupled with specialized OCR-based evaluation metrics. Qwen-Image-VAE-2.0 achieves state-of-the-art reconstruction performance, demonstrating exceptional capabilities in both general domains and text-rich scenarios at high compression ratio. Furthermore, downstream DiT experiments reveal our models possess superior diffusability, significantly accelerating convergence compared to existing high-compression baselines. These establish Qwen-Image-VAE-2.0 as a leading model with high compression, superior reconstruction, and exceptional diffusability.

preprint2024arXiv

FABind: Fast and Accurate Protein-Ligand Binding

Modeling the interaction between proteins and ligands and accurately predicting their binding structures is a critical yet challenging task in drug discovery. Recent advancements in deep learning have shown promise in addressing this challenge, with sampling-based and regression-based methods emerging as two prominent approaches. However, these methods have notable limitations. Sampling-based methods often suffer from low efficiency due to the need for generating multiple candidate structures for selection. On the other hand, regression-based methods offer fast predictions but may experience decreased accuracy. Additionally, the variation in protein sizes often requires external modules for selecting suitable binding pockets, further impacting efficiency. In this work, we propose $\mathbf{FABind}$, an end-to-end model that combines pocket prediction and docking to achieve accurate and fast protein-ligand binding. $\mathbf{FABind}$ incorporates a unique ligand-informed pocket prediction module, which is also leveraged for docking pose estimation. The model further enhances the docking process by incrementally integrating the predicted pocket to optimize protein-ligand binding, reducing discrepancies between training and inference. Through extensive experiments on benchmark datasets, our proposed $\mathbf{FABind}$ demonstrates strong advantages in terms of effectiveness and efficiency compared to existing methods. Our code is available at https://github.com/QizhiPei/FABind

preprint2021arXiv

Revisiting Language Encoding in Learning Multilingual Representations

Transformer has demonstrated its great power to learn contextual word representations for multiple languages in a single model. To process multilingual sentences in the model, a learnable vector is usually assigned to each language, which is called "language embedding". The language embedding can be either added to the word embedding or attached at the beginning of the sentence. It serves as a language-specific signal for the Transformer to capture contextual representations across languages. In this paper, we revisit the use of language embedding and identify several problems in the existing formulations. By investigating the interaction between language embedding and word embedding in the self-attention module, we find that the current methods cannot reflect the language-specific word correlation well. Given these findings, we propose a new approach called Cross-lingual Language Projection (XLP) to replace language embedding. For a sentence, XLP projects the word embeddings into language-specific semantic space, and then the projected embeddings will be fed into the Transformer model to process with their language-specific meanings. In such a way, XLP achieves the purpose of appropriately encoding "language" in a multilingual Transformer model. Experimental results show that XLP can freely and significantly boost the model performance on extensive multilingual benchmark datasets. Codes and models will be released at https://github.com/lsj2408/XLP.

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