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Hongjian Zhou

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3 published item(s)

preprint2026arXiv

BioMedArena: An Open-source Toolkit for Building and Evaluating Biomedical Deep Research Agents

Building a deep research agent today is an exercise in glue code: the same backbone evaluated on the same benchmark can report different accuracies in different papers because harness and tool registry all differ, and integrating a new foundation model into a comparable evaluation surface costs weeks of model-specific engineering. We call this the per-paper engineering tax and release BioMedArena, an open-source toolkit that not only alleviates it but also provides an arena for fair comparison of different foundation models when evaluating them as deep-research agents. BioMedArena decouples six layers of biomedical agent evaluation -- benchmark loading, tool exposure, tool selection, execution mode, context management, and scoring -- and exposes 147 biomedical benchmarks and 75 biomedical tools across 9 functional families. Adding a new model, benchmark, or tool reduces to registering a few-line provider adapter. We further provide 6 agent harnesses with 6 context-management strategies, which provide 12 backbones with competitive research capabilities and significantly improved performance, achieving state-of-the-art (SOTA) results on 8 representative biomedical benchmarks, with an average lift of +15.03 percentage points over prior SOTA. The toolkit, configurations, and per-task traces are available at https://github.com/AI-in-Health/BioMedArena

preprint2025arXiv

Democratizing Electronic-Photonic AI Systems: An Open-Source AI-Infused Cross-Layer Co-Design and Design Automation Toolflow

Photonics is becoming a cornerstone technology for high-performance AI systems and scientific computing, offering unparalleled speed, parallelism, and energy efficiency. Despite this promise, the design and deployment of electronic-photonic AI systems remain highly challenging due to a steep learning curve across multiple layers, spanning device physics, circuit design, system architecture, and AI algorithms. The absence of a mature electronic-photonic design automation (EPDA) toolchain leads to long, inefficient design cycles and limits cross-disciplinary innovation and co-evolution. In this work, we present a cross-layer co-design and automation framework aimed at democratizing photonic AI system development. We begin by introducing our architecture designs for scalable photonic edge AI and Transformer inference, followed by SimPhony, an open-source modeling tool for rapid EPIC AI system evaluation and design-space exploration. We then highlight advances in AI-enabled photonic design automation, including physical AI-based Maxwell solvers, a fabrication-aware inverse design framework, and a scalable inverse training algorithm for meta-optical neural networks, enabling a scalable EPDA stack for next-generation electronic-photonic AI systems.

preprint2025arXiv

Toward Large-Scale Photonics-Empowered AI Systems: From Physical Design Automation to System-Algorithm Co-Exploration

In this work, we identify three considerations that are essential for realizing practical photonic AI systems at scale: (1) dynamic tensor operation support for modern models rather than only weight-static kernels, especially for attention/Transformer-style workloads; (2) systematic management of conversion, control, and data-movement overheads, where multiplexing and dataflow must amortize electronic costs instead of letting ADC/DAC and I/O dominate; and (3) robustness under hardware non-idealities that become more severe as integration density grows. To study these coupled tradeoffs quantitatively, and to ensure they remain meaningful under real implementation constraints, we build a cross-layer toolchain that supports photonic AI design from early exploration to physical realization. SimPhony provides implementation-aware modeling and rapid cross-layer evaluation, translating physical costs into system-level metrics so architectural decisions are grounded in realistic assumptions. ADEPT and ADEPT-Z enable end-to-end circuit and topology exploration, connecting system objectives to feasible photonic fabrics under practical device and circuit constraints. Finally, Apollo and LiDAR provide scalable photonic physical design automation, turning candidate circuits into manufacturable layouts while accounting for routing, thermal, and crosstalk constraints.