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Christoph Brune

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Published work

7 published item(s)

preprint2026arXiv

Manifold limit for the training of shallow graph convolutional neural networks

We study the discrete-to-continuum consistency of the training of shallow graph convolutional neural networks (GCNNs) on proximity graphs of sampled point clouds under a manifold assumption. Graph convolution is defined spectrally via the graph Laplacian, whose low-frequency spectrum approximates that of the Laplace-Beltrami operator of the underlying smooth manifold, and shallow GCNNs of possibly infinite width are linear functionals on the space of measures on the parameter space. From this functional-analytic perspective, graph signals are seen as spatial discretizations of functions on the manifold, which leads to a natural notion of training data consistent across graph resolutions. To enable convergence results, the continuum parameter space is chosen as a weakly compact product of unit balls, with Sobolev regularity imposed on the output weight and bias, but not on the convolutional parameter. The corresponding discrete parameter spaces inherit the corresponding spectral decay, and are additionally restricted by a frequency cutoff adapted to the informative spectral window of the graph Laplacians. Under these assumptions, we prove $Γ$-convergence of regularized empirical risk minimization functionals and corresponding convergence of their global minimizers, in the sense of weak convergence of the parameter measures and uniform convergence of the functions over compact sets. This provides a formalization of mesh and sample independence for the training of such networks.

preprint2026arXiv

Multi-Headed Transformer Architectures as Time-dependent Wasserstein Gradient Flows

In recent years, transformer architectures have revolutionized the field of language processing, opening the door to previously unforeseen possibilities. However, from a theoretical point of view, the mathematical models proposed in the literature often lack direct contact with the actual architectures and depend on strong simplifying assumptions. In this paper, we reduce this gap by modelling the data flow in multi-headed transformer architectures as time-dependent gradient flows for a suitable interaction energy capturing the design of the attention mechanism. The explicit dependence on time allows us to consider different weights for each head and for each layer, without imposing constraints on the initialization method. Moreover, we prove that, under a suitable integrability assumption on the evolution of the weights, each element of the $ω$-limit set of the gradient flows is a stationary point of the interaction energy at a limiting weight distribution. Finally, we analyse the stability of the gradient flows considering perturbations of both the initial data and the weights. Specifically, on the one hand, we study the robustness of the proposed models with respect to noisy inputs, establishing a continuous dependence of the gradient flows on the initial data and uniqueness of the flows. On the other hand, we prove the $Γ$-convergence of the perturbed interaction energy to the unperturbed one, leading to the convergence of the corresponding gradient flows. We complement these theoretical results with numerical experiments that confirm the predicted energy-dissipation identity and clarify the asymptotic behavior of the dynamics in both the autonomous-like (Ornstein--Uhlenbeck) and the genuinely non-autonomous (oscillating-weights) regimes.

preprint2026arXiv

Symmetry in the Wild: The Role of Equivariance in Neural Fluid Surrogates

Neural surrogates enable orders-of-magnitude acceleration of computational fluid dynamics (CFD) simulations, with the potential to transform engineering and healthcare workflows. Neural surrogate use in real-world applications requires addressing scalability to large, high-resolution surface and volume meshes, as well as to bespoke architectures, and accounting for limited training data through the use of inductive biases. Group-equivariant architectures are a principled way to introduce such bias, yet they can be detrimental when the learning problem itself breaks symmetry, for example, due to strong distributional alignment in the dataset. In this work, we investigate under which conditions equivariance improves generalization in neural CFD surrogates across tasks with increasing levels of distributional alignment and realism, covering automotive aerodynamics and blood flow (hemodynamics). To systematically assess the added value of equivariance at the limit of problem scaling, we introduce the Anchored-Branched Geometric Algebra Transformer (AB-GATr), a neural surrogate that integrates scalability and symmetry preservation to efficiently model coupled surface and volume quantities in an $E(3)$-equivariant manner. We find that on strongly aligned aerodynamics datasets, i.e., those that break symmetry, enforcing equivariance can degrade in-distribution performance. In contrast, across hemodynamic benchmarks with diverse geometries and varying alignment, equivariance is consistently beneficial. Moreover, across all benchmarks, the explicit equivariance of AB-GATr reliably outperforms implicit symmetry learning through data augmentation. Our findings showcase that equivariance is not universally beneficial across domains, yet it brings tangible advantages in problems lacking strong data regularities.

preprint2022arXiv

Mesh convolutional neural networks for wall shear stress estimation in 3D artery models

Computational fluid dynamics (CFD) is a valuable tool for personalised, non-invasive evaluation of hemodynamics in arteries, but its complexity and time-consuming nature prohibit large-scale use in practice. Recently, the use of deep learning for rapid estimation of CFD parameters like wall shear stress (WSS) on surface meshes has been investigated. However, existing approaches typically depend on a hand-crafted re-parametrisation of the surface mesh to match convolutional neural network architectures. In this work, we propose to instead use mesh convolutional neural networks that directly operate on the same finite-element surface mesh as used in CFD. We train and evaluate our method on two datasets of synthetic coronary artery models with and without bifurcation, using a ground truth obtained from CFD simulation. We show that our flexible deep learning model can accurately predict 3D WSS vectors on this surface mesh. Our method processes new meshes in less than 5 [s], consistently achieves a normalised mean absolute error of $\leq$ 1.6 [%], and peaks at 90.5 [%] median approximation accuracy over the held-out test set, comparing favourably to previously published work. This demonstrates the feasibility of CFD surrogate modelling using mesh convolutional neural networks for hemodynamic parameter estimation in artery models.

preprint2022arXiv

Super-Resolved Microbubble Localization in Single-Channel Ultrasound RF Signals Using Deep Learning

Recently, super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) has received much attention. However, ULM relies on low concentrations of microbubbles in the blood vessels, ultimately resulting in long acquisition times. Here, we present an alternative super-resolution approach, based on direct deconvolution of single-channel ultrasound radio-frequency (RF) signals with a one-dimensional dilated convolutional neural network (CNN). This work focuses on low-frequency ultrasound (1.7 MHz) for deep imaging (10 cm) of a dense cloud of monodisperse microbubbles (up to 1000 microbubbles in the measurement volume, corresponding to an average echo overlap of 94%). Data are generated with a simulator that uses a large range of acoustic pressures (5-250 kPa) and captures the full, nonlinear response of resonant, lipid-coated microbubbles. The network is trained with a novel dual-loss function, which features elements of both a classification loss and a regression loss and improves the detection-localization characteristics of the output. Whereas imposing a localization tolerance of 0 yields poor detection metrics, imposing a localization tolerance corresponding to 4% of the wavelength yields a precision and recall of both 0.90. Furthermore, the detection improves with increasing acoustic pressure and deteriorates with increasing microbubble density. The potential of the presented approach to super-resolution ultrasound imaging is demonstrated with a delay-and-sum reconstruction with deconvolved element data. The resulting image shows an order-of-magnitude gain in axial resolution compared to a delay-and-sum reconstruction with unprocessed element data.

preprint2016arXiv

Multiscale Segmentation via Bregman Distances and Nonlinear Spectral Analysis

In biomedical imaging reliable segmentation of objects (e.g. from small cells up to large organs) is of fundamental importance for automated medical diagnosis. New approaches for multi-scale segmentation can considerably improve performance in case of natural variations in intensity, size and shape. This paper aims at segmenting objects of interest based on shape contours and automatically finding multiple objects with different scales. The overall strategy of this work is to combine nonlinear segmentation with scales spaces and spectral decompositions recently introduced in literature. For this we generalize a variational segmentation model based on total variation using Bregman distances to construct an inverse scale space. This offers the new model to be accomplished by a scale analysis approach based on a spectral decomposition of the total variation. As a result we obtain a very efficient, (nearly) parameter-free multiscale segmentation method that comes with an adaptive regularization parameter choice. The added benefit of our method is demonstrated by systematic synthetic tests and its usage in a new biomedical toolbox for identifying and classifying circulating tumor cells. Due to the nature of nonlinear diffusion underlying, the mathematical concepts in this work offer promising extensions to nonlocal classification problems.

preprint2014arXiv

Optimal Data Collection For Informative Rankings Expose Well-Connected Graphs

Given a graph where vertices represent alternatives and arcs represent pairwise comparison data, the statistical ranking problem is to find a potential function, defined on the vertices, such that the gradient of the potential function agrees with the pairwise comparisons. Our goal in this paper is to develop a method for collecting data for which the least squares estimator for the ranking problem has maximal Fisher information. Our approach, based on experimental design, is to view data collection as a bi-level optimization problem where the inner problem is the ranking problem and the outer problem is to identify data which maximizes the informativeness of the ranking. Under certain assumptions, the data collection problem decouples, reducing to a problem of finding multigraphs with large algebraic connectivity. This reduction of the data collection problem to graph-theoretic questions is one of the primary contributions of this work. As an application, we study the Yahoo! Movie user rating dataset and demonstrate that the addition of a small number of well-chosen pairwise comparisons can significantly increase the Fisher informativeness of the ranking. As another application, we study the 2011-12 NCAA football schedule and propose schedules with the same number of games which are significantly more informative. Using spectral clustering methods to identify highly-connected communities within the division, we argue that the NCAA could improve its notoriously poor rankings by simply scheduling more out-of-conference games.