Researcher profile

Ardhendu Behera

Ardhendu Behera contributes to research discovery and scholarly infrastructure.

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Published work

6 published item(s)

preprint2026arXiv

Towards Label-Free Single-Cell Phenotyping Using Multi-Task Learning

Label-free single-cell imaging offers a scalable, non-invasive alternative to fluorescence-based cytometry, yet inferring molecular phenotypes directly from bright-field morphology remains challenging. We present a unified Deep Learning (DL) framework that jointly performs White Blood Cell (WBC) classification and continuous protein-expression regression from label-free Differential Phase Contrast (DPC) images. Our model employs a Hybrid architecture that fuses convolutional fine-grained texture features with transformer-based global representations through a learnable cross-branch gating module, enabling robust morpho-molecular inference from DPC images. To support downstream interpretability, we further incorporate a Large Language Model (LLM) that generates concise, biologically grounded summaries of the predicted cell states. Experiments on the Berkeley Single Cell Computational Microscopy (BSCCM) and Blood Cells Image benchmarks demonstrate strong performance, achieving a 91.3% WBC classification accuracy and a 0.72 Pearson correlation for CD16 expression regression on BSCCM. These results underscore the promise of label-free single-cell imaging for cost-effective hematological profiling, enabling simultaneous phenotype identification and quantitative biomarker estimation without fluorescent staining. The source code is available at https://github.com/saqibnaziir/Single-Cell-Phenotyping.

preprint2022arXiv

Benchmarking Deep Reinforcement Learning Algorithms for Vision-based Robotics

This paper presents a benchmarking study of some of the state-of-the-art reinforcement learning algorithms used for solving two simulated vision-based robotics problems. The algorithms considered in this study include soft actor-critic (SAC), proximal policy optimization (PPO), interpolated policy gradients (IPG), and their variants with Hindsight Experience replay (HER). The performances of these algorithms are compared against PyBullet's two simulation environments known as KukaDiverseObjectEnv and RacecarZEDGymEnv respectively. The state observations in these environments are available in the form of RGB images and the action space is continuous, making them difficult to solve. A number of strategies are suggested to provide intermediate hindsight goals required for implementing HER algorithm on these problems which are essentially single-goal environments. In addition, a number of feature extraction architectures are proposed to incorporate spatial and temporal attention in the learning process. Through rigorous simulation experiments, the improvement achieved with these components are established. To the best of our knowledge, such a benchmarking study is not available for the above two vision-based robotics problems making it a novel contribution in the field.

preprint2022arXiv

Retinal Structure Detection in OCTA Image via Voting-based Multi-task Learning

Automated detection of retinal structures, such as retinal vessels (RV), the foveal avascular zone (FAZ), and retinal vascular junctions (RVJ), are of great importance for understanding diseases of the eye and clinical decision-making. In this paper, we propose a novel Voting-based Adaptive Feature Fusion multi-task network (VAFF-Net) for joint segmentation, detection, and classification of RV, FAZ, and RVJ in optical coherence tomography angiography (OCTA). A task-specific voting gate module is proposed to adaptively extract and fuse different features for specific tasks at two levels: features at different spatial positions from a single encoder, and features from multiple encoders. In particular, since the complexity of the microvasculature in OCTA images makes simultaneous precise localization and classification of retinal vascular junctions into bifurcation/crossing a challenging task, we specifically design a task head by combining the heatmap regression and grid classification. We take advantage of three different \textit{en face} angiograms from various retinal layers, rather than following existing methods that use only a single \textit{en face}. To facilitate further research, part of these datasets with the source code and evaluation benchmark have been released for public access:https://github.com/iMED-Lab/VAFF-Net.

preprint2021arXiv

Coarse Temporal Attention Network (CTA-Net) for Driver's Activity Recognition

There is significant progress in recognizing traditional human activities from videos focusing on highly distinctive actions involving discriminative body movements, body-object and/or human-human interactions. Driver's activities are different since they are executed by the same subject with similar body parts movements, resulting in subtle changes. To address this, we propose a novel framework by exploiting the spatiotemporal attention to model the subtle changes. Our model is named Coarse Temporal Attention Network (CTA-Net), in which coarse temporal branches are introduced in a trainable glimpse network. The goal is to allow the glimpse to capture high-level temporal relationships, such as 'during', 'before' and 'after' by focusing on a specific part of a video. These branches also respect the topology of the temporal dynamics in the video, ensuring that different branches learn meaningful spatial and temporal changes. The model then uses an innovative attention mechanism to generate high-level action specific contextual information for activity recognition by exploring the hidden states of an LSTM. The attention mechanism helps in learning to decide the importance of each hidden state for the recognition task by weighing them when constructing the representation of the video. Our approach is evaluated on four publicly accessible datasets and significantly outperforms the state-of-the-art by a considerable margin with only RGB video as input.

preprint2021arXiv

Context-aware Attentional Pooling (CAP) for Fine-grained Visual Classification

Deep convolutional neural networks (CNNs) have shown a strong ability in mining discriminative object pose and parts information for image recognition. For fine-grained recognition, context-aware rich feature representation of object/scene plays a key role since it exhibits a significant variance in the same subcategory and subtle variance among different subcategories. Finding the subtle variance that fully characterizes the object/scene is not straightforward. To address this, we propose a novel context-aware attentional pooling (CAP) that effectively captures subtle changes via sub-pixel gradients, and learns to attend informative integral regions and their importance in discriminating different subcategories without requiring the bounding-box and/or distinguishable part annotations. We also introduce a novel feature encoding by considering the intrinsic consistency between the informativeness of the integral regions and their spatial structures to capture the semantic correlation among them. Our approach is simple yet extremely effective and can be easily applied on top of a standard classification backbone network. We evaluate our approach using six state-of-the-art (SotA) backbone networks and eight benchmark datasets. Our method significantly outperforms the SotA approaches on six datasets and is very competitive with the remaining two.

preprint2021arXiv

Regional Attention Network (RAN) for Head Pose and Fine-grained Gesture Recognition

Affect is often expressed via non-verbal body language such as actions/gestures, which are vital indicators for human behaviors. Recent studies on recognition of fine-grained actions/gestures in monocular images have mainly focused on modeling spatial configuration of body parts representing body pose, human-objects interactions and variations in local appearance. The results show that this is a brittle approach since it relies on accurate body parts/objects detection. In this work, we argue that there exist local discriminative semantic regions, whose "informativeness" can be evaluated by the attention mechanism for inferring fine-grained gestures/actions. To this end, we propose a novel end-to-end \textbf{Regional Attention Network (RAN)}, which is a fully Convolutional Neural Network (CNN) to combine multiple contextual regions through attention mechanism, focusing on parts of the images that are most relevant to a given task. Our regions consist of one or more consecutive cells and are adapted from the strategies used in computing HOG (Histogram of Oriented Gradient) descriptor. The model is extensively evaluated on ten datasets belonging to 3 different scenarios: 1) head pose recognition, 2) drivers state recognition, and 3) human action and facial expression recognition. The proposed approach outperforms the state-of-the-art by a considerable margin in different metrics.