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Andrea Passerini

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Published work

18 published item(s)

preprint2026arXiv

Actionable Real-Time Modeling of Surgical Team Dynamics via Time-Expanded Interaction Graphs

Surgical team performance arises from complex interactions between technical execution and non-technical skills, including communication and coordination dynamics. However, current surgical AI systems predominantly model visual workflow signals, lacking structured representations of intraoperative team interactions over time. We propose a real-time actionable approach for modeling surgical team dynamics using time-expanded interaction graphs, where team members are modeled as time-indexed nodes and communication exchanges define directed edges. This spatio-temporal expansion enables dynamic interaction modeling, while allowing efficient inference with a static graph neural network. The model predicts procedural efficiency as the deviation from the expected duration and supports real-time deployment. Beyond prediction, we perform a counterfactual analysis to identify minimal changes in communication structure and interpretable behavioral variables associated with improved predicted outcomes. Experiments on recorded surgical procedures show that structured modeling of team interactions improves early identification of prolonged interventions and provides coherent, actionable explanations. This work advances surgical AI toward real-time, team-aware, and actionable decision support in the operating room.

preprint2026arXiv

Concepts Worth Having: Refining VLM-Guided Concept Bottleneck Models with Minimal Annotations

Concept-bottleneck models (CBMs) are neural classifiers that compute predictions from high-level concepts extracted from the input. CBMs ensure stakeholders can understand the concepts -- and the predictions they entail -- by learning these from concept-level annotations, which are however seldom available. Recent CBM architectures work around this issue by obtaining annotations from Vision-Language Models (VLMs). While greatly broadening applicability, doing so can yield lower quality concepts and therefore less interpretable models. We strike for a middle ground by introducing Vision-plus-Human-guided CBM (VH-CBM), a hybrid approach that exploits both VLMs and a small amount of dense annotations. VH-CBM employs a Gaussian Process in the VLM's embedding space, which captures useful global information about the target domain, to propagate the expert's supervision to any target data point. Our empirical evaluation shows how VH-CBM predicts more accurate concepts than VLM-guided CBMs even when annotating as little as 1% of the data, while sporting better concept calibration and supporting active learning.

preprint2026arXiv

Concise and Logically Consistent Conformal Sets for Neuro-Symbolic Concept-Based Models

Neuro-Symbolic Concept-based Models (NeSy-CBMs) are a family of architectures that integrate neural networks with symbolic reasoning for enhanced reliability in high-stakes applications. They work by first extracting high-level concepts from the input and then inferring a task label from these compatibly with given logical constraints. Yet, their label and concept predictions can be overconfident, making it difficult for stakeholders to gauge when the model's decisions can be trusted. We address this issue by integrating ideas from Conformal Prediction (CP), a framework providing rigorous, distribution-free coverage guarantees. We formalize three desiderata -- consistency, coverage, and conciseness -- that any conformal method for NeSy-CBMs should satisfy, and show that existing approaches fall short of at least one. We then introduce COCOCO, a post-hoc framework that conformalizes concepts and labels jointly and reconciles them via a single deduction-abduction revision step. COCOCO satisfies all three desiderata, retains distribution-free coverage, is robust to imperfect knowledge and supports user-specified size budgets. Our experiments on 8 data sets highlight how COCOCO compares favorably against competitors and natural baselines in terms of performance and set size.

preprint2026arXiv

Human-LLM Dialogue Improves Diagnostic Accuracy in Emergency Care

Clinical decision-making in emergency medicine demands rapid, accurate diagnoses under uncertainty. Despite benchmark progress, evidence for LLMs as interactive aids in live physician workflows remains sparse. MedSyn lets physicians iteratively query an LLM provided with the full clinical record while initially viewing only the chief complaint. Seven physicians (three seniors, four residents) completed baseline and AI-assisted sessions across 52 MIMIC-IV cases stratified by difficulty. Blinded evaluation showed residents' Hard-case correctness rose from 0.589 to 0.734; difficulty-standardised completely-correct rates confirmed a medium effect (Δ = 0.092; p = 0.071; d = 0.47). Automated metrics corroborated these gains: standardised any-match accuracy improved by 0.156 (p < 0.0001), and residents showed the largest F1 gain (Δ = 0.138; p < 0.0001). Dialogue analysis revealed expertise-dependent strategies (seniors asked targeted, hypothesis-driven questions; residents relied on broader queries) and cross-expertise concordance increased (Δ = 0.145; p < 0.0001). Interactive LLM support meaningfully enhances diagnostic reasoning.

preprint2026arXiv

Shortcuts and Identifiability in Concept-based Models from a Neuro-Symbolic Lens

Concept-based Models are neural networks that learn a concept extractor to map inputs to high-level concepts and an inference layer to translate these into predictions. Ensuring these modules produce interpretable concepts and behave reliably in out-of-distribution is crucial, yet the conditions for achieving this remain unclear. We study this problem by establishing a novel connection between Concept-based Models and reasoning shortcuts (RSs), a common issue where models achieve high accuracy by learning low-quality concepts, even when the inference layer is fixed and provided upfront. Specifically, we extend RSs to the more complex setting of Concept-based Models and derive theoretical conditions for identifying both the concepts and the inference layer. Our empirical results highlight the impact of RSs and show that existing methods, even combined with multiple natural mitigation strategies, often fail to meet these conditions in practice.

preprint2022arXiv

Lifelong Personal Context Recognition

We focus on the development of AIs which live in lifelong symbiosis with a human. The key prerequisite for this task is that the AI understands - at any moment in time - the personal situational context that the human is in. We outline the key challenges that this task brings forth, namely (i) handling the human-like and ego-centric nature of the the user's context, necessary for understanding and providing useful suggestions, (ii) performing lifelong context recognition using machine learning in a way that is robust to change, and (iii) maintaining alignment between the AI's and human's representations of the world through continual bidirectional interaction. In this short paper, we summarize our recent attempts at tackling these challenges, discuss the lessons learned, and highlight directions of future research. The main take-away message is that pursuing this project requires research which lies at the intersection of knowledge representation and machine learning. Neither technology can achieve this goal without the other.

preprint2022arXiv

Machine Learning for Combinatorial Optimisation of Partially-Specified Problems: Regret Minimisation as a Unifying Lens

It is increasingly common to solve combinatorial optimisation problems that are partially-specified. We survey the case where the objective function or the relations between variables are not known or are only partially specified. The challenge is to learn them from available data, while taking into account a set of hard constraints that a solution must satisfy, and that solving the optimisation problem (esp. during learning) is computationally very demanding. This paper overviews four seemingly unrelated approaches, that can each be viewed as learning the objective function of a hard combinatorial optimisation problem: 1) surrogate-based optimisation, 2) empirical model learning, 3) decision-focused learning (`predict + optimise'), and 4) structured-output prediction. We formalise each learning paradigm, at first in the ways commonly found in the literature, and then bring the formalisations together in a compatible way using regret. We discuss the differences and interactions between these frameworks, highlight the opportunities for cross-fertilization and survey open directions.

preprint2022arXiv

SMT-based Weighted Model Integration with Structure Awareness

Weighted Model Integration (WMI) is a popular formalism aimed at unifying approaches for probabilistic inference in hybrid domains, involving logical and algebraic constraints. Despite a considerable amount of recent work, allowing WMI algorithms to scale with the complexity of the hybrid problem is still a challenge. In this paper we highlight some substantial limitations of existing state-of-the-art solutions, and develop an algorithm that combines SMT-based enumeration, an efficient technique in formal verification, with an effective encoding of the problem structure. This allows our algorithm to avoid generating redundant models, resulting in substantial computational savings. An extensive experimental evaluation on both synthetic and real-world datasets confirms the advantage of the proposed solution over existing alternatives.

preprint2022arXiv

Toward a Unified Framework for Debugging Concept-based Models

In this paper, we tackle interactive debugging of "gray-box" concept-based models (CBMs). These models learn task-relevant concepts appearing in the inputs and then compute a prediction by aggregating the concept activations. Our work stems from the observation that in CBMs both the concepts and the aggregation function can be affected by different kinds of bugs, and that fixing these bugs requires different kinds of corrective supervision. To this end, we introduce a simple schema for human supervisors to identify and prioritize bugs in both components, and discuss solution strategies and open problems. We also introduce a novel loss function for debugging the aggregation step that generalizes existing strategies for aligning black-box models to CBMs by making them robust to how the concepts change during training.

preprint2020arXiv

A chemically etched corrugated feedhorn array for D-band CMB observations

We present the design, manufacturing, and testing of a 37-element array of corrugated feedhorns for Cosmic Microwave Background (CMB) measurements between $140$ and $170$ GHz. The array was designed to be coupled to Kinetic Inductance Detector arrays, either directly (for total power measurements) or through an orthomode transducer (for polarization measurements). We manufactured the array in platelets by chemically etching aluminum plates of $0.3$ mm and $0.4$ mm thickness. The process is fast, low-cost, scalable, and yields high-performance antennas compared to other techniques in the same frequency range. Room temperature electromagnetic measurements show excellent repeatability with an average cross polarization level about $-20$ dB, return loss about $-25$ dB, first sidelobes below $-25$ dB and far sidelobes below $-35$ dB. Our results qualify this process as a valid candidate for state-of-the-art CMB experiments, where large detector arrays with high sensitivity and polarization purity are of paramount importance in the quest for the discovery of CMB polarization $B$-modes.

preprint2020arXiv

Continual egocentric object recognition

We present a framework capable of tackilng the problem of continual object recognition in a setting which resembles that under whichhumans see and learn. This setting has a set of unique characteristics:it assumes an egocentric point-of-view bound to the needs of a singleperson, which implies a relatively low diversity of data and a coldstart with no data; it requires to operate in an open world, where newobjects can be encounteredat any time; supervision is scarce and hasto be solicited to the user, and completelyunsupervised recognitionof new objects should be possible. Note that this setting differs fromthe one addressed in the open world recognition literature, where supervised feedback is always requested to be able to incorporate newobjects. We propose a first solution to this problem in the form ofa memory-based incremental framework that is capable of storinginformation of each and any object it encounters, while using the supervision of the user to learn to discriminate between known and unknown objects. Our approach is based on four main features: the useof time and space persistence (i.e., the appearance of objects changesrelatively slowly), the use of similarity as the main driving principlefor object recognition and novelty detection, the progressive introduction of new objects in a developmental fashion and the selectiveelicitation of user feedback in an online active learning fashion. Experimental results show the feasibility of open world, generic objectrecognition, the ability to recognize, memorize and re-identify newobjects even in complete absence of user supervision, and the utilityof persistence and incrementality in boosting performance.

preprint2020arXiv

Give more data, awareness and control to individual citizens, and they will help COVID-19 containment

The rapid dynamics of COVID-19 calls for quick and effective tracking of virus transmission chains and early detection of outbreaks, especially in the phase 2 of the pandemic, when lockdown and other restriction measures are progressively withdrawn, in order to avoid or minimize contagion resurgence. For this purpose, contact-tracing apps are being proposed for large scale adoption by many countries. A centralized approach, where data sensed by the app are all sent to a nation-wide server, raises concerns about citizens' privacy and needlessly strong digital surveillance, thus alerting us to the need to minimize personal data collection and avoiding location tracking. We advocate the conceptual advantage of a decentralized approach, where both contact and location data are collected exclusively in individual citizens' "personal data stores", to be shared separately and selectively, voluntarily, only when the citizen has tested positive for COVID-19, and with a privacy preserving level of granularity. This approach better protects the personal sphere of citizens and affords multiple benefits: it allows for detailed information gathering for infected people in a privacy-preserving fashion; and, in turn this enables both contact tracing, and, the early detection of outbreak hotspots on more finely-granulated geographic scale. Our recommendation is two-fold. First to extend existing decentralized architectures with a light touch, in order to manage the collection of location data locally on the device, and allow the user to share spatio-temporal aggregates - if and when they want, for specific aims - with health authorities, for instance. Second, we favour a longer-term pursuit of realizing a Personal Data Store vision, giving users the opportunity to contribute to collective good in the measure they want, enhancing self-awareness, and cultivating collective efforts for rebuilding society.

preprint2016arXiv

Coactive Critiquing: Elicitation of Preferences and Features

When faced with complex choices, users refine their own preference criteria as they explore the catalogue of options. In this paper we propose an approach to preference elicitation suited for this scenario. We extend Coactive Learning, which iteratively collects manipulative feedback, to optionally query example critiques. User critiques are integrated into the learning model by dynamically extending the feature space. Our formulation natively supports constructive learning tasks, where the option catalogue is generated on-the-fly. We present an upper bound on the average regret suffered by the learner. Our empirical analysis highlights the promise of our approach.

preprint2016arXiv

Constructive Preference Elicitation by Setwise Max-margin Learning

In this paper we propose an approach to preference elicitation that is suitable to large configuration spaces beyond the reach of existing state-of-the-art approaches. Our setwise max-margin method can be viewed as a generalization of max-margin learning to sets, and can produce a set of "diverse" items that can be used to ask informative queries to the user. Moreover, the approach can encourage sparsity in the parameter space, in order to favor the assessment of utility towards combinations of weights that concentrate on just few features. We present a mixed integer linear programming formulation and show how our approach compares favourably with Bayesian preference elicitation alternatives and easily scales to realistic datasets.

preprint2016arXiv

Interpretability in Linear Brain Decoding

Improving the interpretability of brain decoding approaches is of primary interest in many neuroimaging studies. Despite extensive studies of this type, at present, there is no formal definition for interpretability of brain decoding models. As a consequence, there is no quantitative measure for evaluating the interpretability of different brain decoding methods. In this paper, we present a simple definition for interpretability of linear brain decoding models. Then, we propose to combine the interpretability and the performance of the brain decoding into a new multi-objective criterion for model selection. Our preliminary results on the toy data show that optimizing the hyper-parameters of the regularized linear classifier based on the proposed criterion results in more informative linear models. The presented definition provides the theoretical background for quantitative evaluation of interpretability in linear brain decoding.

preprint2015arXiv

Learning Modulo Theories for preference elicitation in hybrid domains

This paper introduces CLEO, a novel preference elicitation algorithm capable of recommending complex objects in hybrid domains, characterized by both discrete and continuous attributes and constraints defined over them. The algorithm assumes minimal initial information, i.e., a set of catalog attributes, and defines decisional features as logic formulae combining Boolean and algebraic constraints over the attributes. The (unknown) utility of the decision maker (DM) is modelled as a weighted combination of features. CLEO iteratively alternates a preference elicitation step, where pairs of candidate solutions are selected based on the current utility model, and a refinement step where the utility is refined by incorporating the feedback received. The elicitation step leverages a Max-SMT solver to return optimal hybrid solutions according to the current utility model. The refinement step is implemented as learning to rank, and a sparsifying norm is used to favour the selection of few informative features in the combinatorial space of candidate decisional features. CLEO is the first preference elicitation algorithm capable of dealing with hybrid domains, thanks to the use of Max-SMT technology, while retaining uncertainty in the DM utility and noisy feedback. Experimental results on complex recommendation tasks show the ability of CLEO to quickly focus towards optimal solutions, as well as its capacity to recover from suboptimal initial choices. While no competitors exist in the hybrid setting, CLEO outperforms a state-of-the-art Bayesian preference elicitation algorithm when applied to a purely discrete task.

preprint2014arXiv

Hybrid SRL with Optimization Modulo Theories

Generally speaking, the goal of constructive learning could be seen as, given an example set of structured objects, to generate novel objects with similar properties. From a statistical-relational learning (SRL) viewpoint, the task can be interpreted as a constraint satisfaction problem, i.e. the generated objects must obey a set of soft constraints, whose weights are estimated from the data. Traditional SRL approaches rely on (finite) First-Order Logic (FOL) as a description language, and on MAX-SAT solvers to perform inference. Alas, FOL is unsuited for con- structive problems where the objects contain a mixture of Boolean and numerical variables. It is in fact difficult to implement, e.g. linear arithmetic constraints within the language of FOL. In this paper we propose a novel class of hybrid SRL methods that rely on Satisfiability Modulo Theories, an alternative class of for- mal languages that allow to describe, and reason over, mixed Boolean-numerical objects and constraints. The resulting methods, which we call Learning Mod- ulo Theories, are formulated within the structured output SVM framework, and employ a weighted SMT solver as an optimization oracle to perform efficient in- ference and discriminative max margin weight learning. We also present a few examples of constructive learning applications enabled by our method.

preprint2014arXiv

Structured Learning Modulo Theories

Modelling problems containing a mixture of Boolean and numerical variables is a long-standing interest of Artificial Intelligence. However, performing inference and learning in hybrid domains is a particularly daunting task. The ability to model this kind of domains is crucial in "learning to design" tasks, that is, learning applications where the goal is to learn from examples how to perform automatic {\em de novo} design of novel objects. In this paper we present Structured Learning Modulo Theories, a max-margin approach for learning in hybrid domains based on Satisfiability Modulo Theories, which allows to combine Boolean reasoning and optimization over continuous linear arithmetical constraints. The main idea is to leverage a state-of-the-art generalized Satisfiability Modulo Theory solver for implementing the inference and separation oracles of Structured Output SVMs. We validate our method on artificial and real world scenarios.