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Adam J. Rothman

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Computation Machine Learning Methodology math.ST Statistics Theory

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preprint2026arXiv

Nonparametric estimation of time-varying network connections by multi-stage smoothing

We consider the problem of estimating the underlying edge probabilities of a time-varying network observed at multiple time points. The probability structure is represented by a time-varying graphon that satisfies temporal Hölder smoothness and piecewise Lipschitz conditions in the latent variables. We propose a multi-stage smoothing estimator that first applies temporal local smoothing to each edge and then performs node-domain smoothing using a data-driven neighborhood construction adapted from the method. An additional temporal smoothing step is introduced as an optional refinement when uniform accuracy over the entire time domain is required. Simulation studies demonstrate the benefits of combining temporal and node-domain smoothing under different generative models. We also apply the method to a real time-varying network dataset and show that it captures both smooth temporal evolution and structural patterns in the connectivity.

preprint2022arXiv

A likelihood-based approach for multivariate categorical response regression in high dimensions

We propose a penalized likelihood method to fit the bivariate categorical response regression model. Our method allows practitioners to estimate which predictors are irrelevant, which predictors only affect the marginal distributions of the bivariate response, and which predictors affect both the marginal distributions and log odds ratios. To compute our estimator, we propose an efficient first order algorithm which we extend to settings where some subjects have only one response variable measured, i.e., the semi-supervised setting. We derive an asymptotic error bound which illustrates the performance of our estimator in high-dimensional settings. Generalizations to the multivariate categorical response regression model are proposed. Finally, simulation studies and an application in pan-cancer risk prediction demonstrate the usefulness of our method in terms of interpretability and prediction accuracy. An R package implementing the proposed method is available for download at github.com/ajmolstad/BvCategorical.

preprint2016arXiv

A penalized likelihood method for classification with matrix-valued predictors

We propose a penalized likelihood method to fit the linear discriminant analysis model when the predictor is matrix valued. We simultaneously estimate the means and the precision matrix, which we assume has a Kronecker product decomposition. Our penalties encourage pairs of response category mean matrices to have equal entries and also encourage zeros in the precision matrix. To compute our estimators, we use a blockwise coordinate descent algorithm. To update the optimization variables corresponding to response category mean matrices, we use an alternating minimization algorithm that takes advantage of the Kronecker structure of the precision matrix. We show that our method can outperform relevant competitors in classification, even when our modeling assumptions are violated. We analyze an EEG dataset to demonstrate our method's interpretability and classification accuracy.

preprint2015arXiv

Indirect multivariate response linear regression

We propose a new class of estimators of the multivariate response linear regression coefficient matrix that exploits the assumption that the response and predictors have a joint multivariate Normal distribution. This allows us to indirectly estimate the regression coefficient matrix through shrinkage estimation of the parameters of the inverse regression, or the conditional distribution of the predictors given the responses. We establish a convergence rate bound for estimators in our class and we study two examples. The first example estimator exploits an assumption that the inverse regression's coefficient matrix is sparse. The second example estimator exploits an assumption that the inverse regression's coefficient matrix is rank deficient. These estimators do not require the popular assumption that the forward regression coefficient matrix is sparse or has small Frobenius norm. Using simulation studies, we show that our example estimators outperform relevant competitors for some data generating models.

preprint2014arXiv

Ridge Fusion in Statistical Learning

We propose a penalized likelihood method to jointly estimate multiple precision matrices for use in quadratic discriminant analysis and model based clustering. A ridge penalty and a ridge fusion penalty are used to introduce shrinkage and promote similarity between precision matrix estimates. Block-wise coordinate descent is used for optimization, and validation likelihood is used for tuning parameter selection. Our method is applied in quadratic discriminant analysis and semi-supervised model based clustering.

preprint2012arXiv

Estimating sufficient reductions of the predictors in abundant high-dimensional regressions

We study the asymptotic behavior of a class of methods for sufficient dimension reduction in high-dimension regressions, as the sample size and number of predictors grow in various alignments. It is demonstrated that these methods are consistent in a variety of settings, particularly in abundant regressions where most predictors contribute some information on the response, and oracle rates are possible. Simulation results are presented to support the theoretical conclusion.