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Paper detail

Real-Time Detection of Deoxyribonucleic Acid Bases via their Negative Differential Conductance Signature

In this paper we present a method for the real-time detection of the bases of the deoxyribonucleic acid using their signatures in negative differential conductance measurements. The present methods of electronic detection of deoxyribonucleic acid bases are based on a statistical analysis because the electrical currents of the four bases are weak and do not differ significantly from one base to another. In contrast, we analyze a device that combines the accumulated knowledge in nanopore and scanning tunneling detection, and which is able to provide very distinctive electronic signatures for the four bases.

preprint2009arXivOpen access
Daniela DragomanMircea Dragoman
cond-mat.mes-hallBiological Physicscond-mat.mtrl-sci
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Daniela DragomanMircea Dragoman

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