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Modeling the mechano-chemistry of the ϕ29 DNA translocation motor

We present a study of the DNA translocation of the bacteriophage ϕ29 packaging molecular motor. From the experimental available information we present a model system based in an stochastic fashing potential, which reproduces the experimental observations such as: detailed trajectories, steps and substeps, spatial correlation, and velocity. Moreover the model allows the evaluation of power and efficiency of this motor. We have found that the maximum power regime does not correspond with that of the maximum efficiency. These informations can stimulate further experiments.

preprint2013arXivOpen access
R. Perez-CarrascoA. FiasconaroF. FaloJ. M. Sancho
cond-mat.stat-mechBiological PhysicsBiomolecules
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R. Perez-CarrascoA. FiasconaroF. FaloJ. M. Sancho

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