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Impact of Tandem Repeats on the Scaling of Nucleotide Sequences

Techniques such as detrended fluctuation analysis (DFA) and its extensions have been widely used to determine the nature of scaling in nucleotide sequences. In this brief communication we show that tandem repeats which are ubiquitous in nucleotide sequences can prevent reliable estimation of possible long-range correlations. Therefore, it is important to investigate the presence of tandem repeats prior to scaling exponent estimation.

preprint2005arXivOpen access
Radhakrishnan NagarajanMeenakshi Upreti
cond-mat.stat-mechGenomics
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Radhakrishnan NagarajanMeenakshi Upreti

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