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Paper detail

Dynamic and thermodynamic bounds for collective motor-driven transport

Molecular motors work collectively to transport cargo within cells, with anywhere from one to several hundred motors towing a single cargo. For a broad class of collective-transport systems, we use tools from stochastic thermodynamics to derive a new lower bound for the entropy production rate which is tighter than the second law. This implies new bounds on the velocity, efficiency, and precision of general transport systems and a set of analytic Pareto frontiers for identical motors. In a specific model, we identify conditions for saturation of these Pareto frontiers.

preprint2022arXivOpen access
Matthew P. LeightonDavid A. Sivak
cond-mat.stat-mechQuantitative Methods
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Matthew P. LeightonDavid A. Sivak

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