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Zhe Ding

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2 published item(s)

preprint2026arXiv

CoQuant: Joint Weight-Activation Subspace Projection for Mixed-Precision LLMs

Post-training quantization (PTQ) has become an important technique for reducing the inference cost of Large Language Models (LLMs). While recent mixed-precision methods improve ultra-low bit quantization by preserving critical subspaces in high precision, they typically construct these subspaces relying solely on activation statistics. This ignores the fundamental nature of linear operations, where the output perturbation is jointly driven by both activation and weight quantization noise. In this paper, we propose CoQuant, a joint weight-activation subspace projection method. By theoretically modeling the expected output error, CoQuant formulates a closed-form weighted PCA solution that balances activation and weight covariances to select the optimal high-precision subspace. Extensive experiments on Llama-3.2 and Qwen2.5 models show that CoQuant consistently outperforms strong PTQ baselines in both WikiText perplexity and zero-shot common-sense reasoning accuracy. These results demonstrate that joint weight-activation subspace modeling provides a principled and effective direction for low-bit LLM quantization. The source code is available at https://github.com/Zachary5895/CoQuant.

preprint2022arXiv

Skipping the boundary layer: high-speed droplet-based immunoassay using Rayleigh acoustic streaming

Acoustic mixing of droplets is a promising way to implement biosensors that combine high speed and minimal reagent consumption. To date, this type of droplet mixing is driven by a volume force resulting from the absorption of high-frequency acoustic waves in the bulk of the fluid. Here, we show that the speed of these sensors is limited by the slow advection of analyte to the sensor surface due to the formation of a hydrodynamic boundary layer. We eliminate this hydrodynamic boundary layer by using much lower ultrasonic frequencies to excite the droplet, which drives a Rayleigh streaming that behaves essentially like a slip velocity. Three-dimensional simulations show that this provides a threefold speedup compared to Eckart streaming. Experimentally, we shorten a SARS-CoV-2 antibody immunoassay from 20 min to 40 s.