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Yugyung Lee

Yugyung Lee contributes to research discovery and scholarly infrastructure.

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Published work

7 published item(s)

preprint2026arXiv

Clinical Knowledge Graph Construction and Evaluation with Multi-LLMs via Retrieval-Augmented Generation

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy and semantic consistency, limitations that are especially problematic in oncology. We introduce an end-to-end framework for clinical KG construction and evaluation directly from free text using multi-agent prompting and a schema-constrained Retrieval-Augmented Generation (KG-RAG) strategy. Our pipeline integrates (1) prompt-driven entity, attribute, and relation extraction; (2) entropy-based uncertainty scoring; (3) ontology-aligned RDF/OWL schema generation; and (4) multi-LLM consensus validation for hallucination detection and semantic refinement. Beyond static graph construction, the framework supports continuous refinement and self-supervised evaluation, enabling iterative improvement of graph quality. Applied to two oncology cohorts (PDAC and BRCA), our method produces interpretable, SPARQL-compatible, and clinically grounded knowledge graphs without relying on gold-standard annotations. Experimental results demonstrate consistent gains in precision, relevance, and ontology compliance over baseline methods.

preprint2026arXiv

MATEX: Multi-scale Attention and Text-guided Explainability of Medical Vision-Language Models

We introduce MATEX (Multi-scale Attention and Text-guided Explainability), a novel framework that advances interpretability in medical vision-language models by incorporating anatomically informed spatial reasoning. MATEX synergistically combines multi-layer attention rollout, text-guided spatial priors, and layer consistency analysis to produce precise, stable, and clinically meaningful gradient attribution maps. By addressing key limitations of prior methods, such as spatial imprecision, lack of anatomical grounding, and limited attention granularity, MATEX enables more faithful and interpretable model explanations. Evaluated on the MS-CXR dataset, MATEX outperforms the state-of-the-art M2IB approach in both spatial precision and alignment with expert-annotated findings. These results highlight MATEX's potential to enhance trust and transparency in radiological AI applications.

preprint2026arXiv

Predicting When to Trust Vision-Language Models for Spatial Reasoning

Vision-Language Models (VLMs) demonstrate impressive capabilities across multimodal tasks, yet exhibit systematic spatial reasoning failures, achieving only 49% (CLIP) to 54% (BLIP-2) accuracy on basic directional relationships. For safe deployment in robotics and autonomous systems, we need to predict when to trust VLM spatial predictions rather than accepting all outputs. We propose a vision-based confidence estimation framework that validates VLM predictions through independent geometric verification using object detection. Unlike text-based approaches relying on self-assessment, our method fuses four signals via gradient boosting: geometric alignment between VLM claims and coordinates, spatial ambiguity from overlap, detection quality, and VLM internal uncertainty. We achieve 0.674 AUROC on BLIP-2 (34.0% improvement over text-based baselines) and 0.583 AUROC on CLIP (16.1% improvement), generalizing across generative and classification architectures. Our framework enables selective prediction: at 60% target accuracy, we achieve 61.9% coverage versus 27.6% baseline (2.2x improvement) on BLIP-2. Feature analysis reveals vision-based signals contribute 87.4% of model importance versus 12.7% from VLM confidence, validating that external geometric verification outperforms self-assessment. We demonstrate reliable scene graph construction where confidence-based pruning improves precision from 52.1% to 78.3% while retaining 68.2% of edges.

preprint2026arXiv

SEMIR: Semantic Minor-Induced Representation Learning on Graphs for Visual Segmentation

Segmenting small and sparse structures in large-scale images is fundamentally constrained by voxel-level, lattice-bound computation and extreme class imbalance -- dense, full-resolution inference scales poorly and forces most pipelines to rely on fixed regionization or downsampling, coupling computational cost to image resolution and attenuating boundary evidence precisely where minority structures are most informative. We introduce SEMIR (Semantic Minor-Induced Representation Learning), a representation framework that decouples inference from the native grid by learning a task-adapted, topology-preserving latent graph representation with exact decoding. SEMIR transforms the underlying grid graph into a compact, boundary-aligned graph minor through parameterized edge contraction, node deletion, and edge deletion, while preserving an exact lifting map from minor predictions to lattice labels. Minor construction is formalized as a few-shot structure learning problem that replaces hand-tuned preprocessing with a boundary-alignment objective: minor parameters are learned by maximizing agreement between predicted boundary elements and target-specific semantic edges under a boundary Dice criterion, and the induced minor is annotated with scale- and rotation-robust geometric and intensity descriptors and supports efficient region-level inference via message passing on a graph neural network (GNN) with relational edge features. We benchmark SEMIR on three tumor segmentation datasets -- BraTS 2021, KiTS23, and LiTS -- where targets exhibit high structural variability and distributional uncertainty. SEMIR yields consistent improvements in minority-structure Dice at practical runtime. More broadly, SEMIR establishes a framework for learning task-adapted, topology-preserving latent representations with exact decoding for high-resolution structured visual data.

preprint2020arXiv

CRL: Class Representative Learning for Image Classification

Building robust and real-time classifiers with diverse datasets are one of the most significant challenges to deep learning researchers. It is because there is a considerable gap between a model built with training (seen) data and real (unseen) data in applications. Recent works including Zero-Shot Learning (ZSL), have attempted to deal with this problem of overcoming the apparent gap through transfer learning. In this paper, we propose a novel model, called Class Representative Learning Model (CRL), that can be especially effective in image classification influenced by ZSL. In the CRL model, first, the learning step is to build class representatives to represent classes in datasets by aggregating prominent features extracted from a Convolutional Neural Network (CNN). Second, the inferencing step in CRL is to match between the class representatives and new data. The proposed CRL model demonstrated superior performance compared to the current state-of-the-art research in ZSL and mobile deep learning. The proposed CRL model has been implemented and evaluated in a parallel environment, using Apache Spark, for both distributed learning and recognition. An extensive experimental study on the benchmark datasets, ImageNet-1K, CalTech-101, CalTech-256, CIFAR-100, shows that CRL can build a class distribution model with drastic improvement in learning and recognition performance without sacrificing accuracy compared to the state-of-the-art performances in image classification.

preprint2020arXiv

Link Prediction for Temporally Consistent Networks

Dynamic networks have intrinsic structural, computational, and multidisciplinary advantages. Link prediction estimates the next relationship in dynamic networks. However, in the current link prediction approaches, only bipartite or non-bipartite but homogeneous networks are considered. The use of adjacency matrix to represent dynamically evolving networks limits the ability to analytically learn from heterogeneous, sparse, or forming networks. In the case of a heterogeneous network, modeling all network states using a binary-valued matrix can be difficult. On the other hand, sparse or currently forming networks have many missing edges, which are represented as zeros, thus introducing class imbalance or noise. We propose a time-parameterized matrix (TP-matrix) and empirically demonstrate its effectiveness in non-bipartite, heterogeneous networks. In addition, we propose a predictive influence index as a measure of a node's boosting or diminishing predictive influence using backward and forward-looking maximization over the temporal space of the n-degree neighborhood. We further propose a new method of canonically representing heterogeneous time-evolving activities as a temporally parameterized network model (TPNM). The new method robustly enables activities to be represented as a form of a network, thus potentially inspiring new link prediction applications, including intelligent business process management systems and context-aware workflow engines. We evaluated our model on four datasets of different network systems. We present results that show the proposed model is more effective in capturing and retaining temporal relationships in dynamically evolving networks. We also show that our model performed better than state-of-the-art link prediction benchmark results for networks that are sensitive to temporal evolution.

preprint2020arXiv

SCAT: Second Chance Autoencoder for Textual Data

We present a k-competitive learning approach for textual autoencoders named Second Chance Autoencoder (SCAT). SCAT selects the $k$ largest and smallest positive activations as the winner neurons, which gain the activation values of the loser neurons during the learning process, and thus focus on retrieving well-representative features for topics. Our experiments show that SCAT achieves outstanding performance in classification, topic modeling, and document visualization compared to LDA, K-Sparse, NVCTM, and KATE.