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Yuanhong Chen

Yuanhong Chen contributes to research discovery and scholarly infrastructure.

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Published work

10 published item(s)

preprint2026arXiv

People-Centred Medical Image Analysis

Recent advances in data-centric medical AI have produced highly accurate diagnostic systems, but the emphasis on data curation and performance metrics has not translated into widespread clinical adoption. We conjecture that this limited uptake stems from insufficient attention dedicated to the optimisation of fair performance across diverse patient populations and to workflow integration: performance biases can create regulatory barriers, and poorly integrated automation can disrupt clinical routines, degrade the quality of human-AI collaboration, and reduce clinicians' willingness to adopt AI tools. Prior work on workflow integration (e.g., Learning to Defer (L2D) and Learning to Complement (L2C)) and AI fairness has typically examined these challenges in isolation, overlooking their natural interdependence and the practical constraints of clinical environments, such as restricted clinician availability. We propose People-Centred Medical Image Analysis (PecMan), a human-AI framework that jointly optimises fairness, diagnostic accuracy, and workflow effectiveness through a dynamic gating mechanism that assigns cases to AI, clinicians, or both under clinician workload constraints. We also introduce the Fairness and Human-Centred AI (FairHAI) benchmark for evaluating trade-offs between accuracy, fairness, and clinician workload. Experiments using this benchmark show that PecMan consistently outperforms existing methods, paving the way for more trustworthy and clinically viable AI systems. Code will be available upon paper acceptance.

preprint2023arXiv

Asymmetric Co-teaching with Multi-view Consensus for Noisy Label Learning

Learning with noisy-labels has become an important research topic in computer vision where state-of-the-art (SOTA) methods explore: 1) prediction disagreement with co-teaching strategy that updates two models when they disagree on the prediction of training samples; and 2) sample selection to divide the training set into clean and noisy sets based on small training loss. However, the quick convergence of co-teaching models to select the same clean subsets combined with relatively fast overfitting of noisy labels may induce the wrong selection of noisy label samples as clean, leading to an inevitable confirmation bias that damages accuracy. In this paper, we introduce our noisy-label learning approach, called Asymmetric Co-teaching (AsyCo), which introduces novel prediction disagreement that produces more consistent divergent results of the co-teaching models, and a new sample selection approach that does not require small-loss assumption to enable a better robustness to confirmation bias than previous methods. More specifically, the new prediction disagreement is achieved with the use of different training strategies, where one model is trained with multi-class learning and the other with multi-label learning. Also, the new sample selection is based on multi-view consensus, which uses the label views from training labels and model predictions to divide the training set into clean and noisy for training the multi-class model and to re-label the training samples with multiple top-ranked labels for training the multi-label model. Extensive experiments on synthetic and real-world noisy-label datasets show that AsyCo improves over current SOTA methods.

preprint2023arXiv

Knowledge Distillation to Ensemble Global and Interpretable Prototype-Based Mammogram Classification Models

State-of-the-art (SOTA) deep learning mammogram classifiers, trained with weakly-labelled images, often rely on global models that produce predictions with limited interpretability, which is a key barrier to their successful translation into clinical practice. On the other hand, prototype-based models improve interpretability by associating predictions with training image prototypes, but they are less accurate than global models and their prototypes tend to have poor diversity. We address these two issues with the proposal of BRAIxProtoPNet++, which adds interpretability to a global model by ensembling it with a prototype-based model. BRAIxProtoPNet++ distills the knowledge of the global model when training the prototype-based model with the goal of increasing the classification accuracy of the ensemble. Moreover, we propose an approach to increase prototype diversity by guaranteeing that all prototypes are associated with different training images. Experiments on weakly-labelled private and public datasets show that BRAIxProtoPNet++ has higher classification accuracy than SOTA global and prototype-based models. Using lesion localisation to assess model interpretability, we show BRAIxProtoPNet++ is more effective than other prototype-based models and post-hoc explanation of global models. Finally, we show that the diversity of the prototypes learned by BRAIxProtoPNet++ is superior to SOTA prototype-based approaches.

preprint2022arXiv

ACPL: Anti-curriculum Pseudo-labelling for Semi-supervised Medical Image Classification

Effective semi-supervised learning (SSL) in medical image analysis (MIA) must address two challenges: 1) work effectively on both multi-class (e.g., lesion classification) and multi-label (e.g., multiple-disease diagnosis) problems, and 2) handle imbalanced learning (because of the high variance in disease prevalence). One strategy to explore in SSL MIA is based on the pseudo labelling strategy, but it has a few shortcomings. Pseudo-labelling has in general lower accuracy than consistency learning, it is not specifically designed for both multi-class and multi-label problems, and it can be challenged by imbalanced learning. In this paper, unlike traditional methods that select confident pseudo label by threshold, we propose a new SSL algorithm, called anti-curriculum pseudo-labelling (ACPL), which introduces novel techniques to select informative unlabelled samples, improving training balance and allowing the model to work for both multi-label and multi-class problems, and to estimate pseudo labels by an accurate ensemble of classifiers (improving pseudo label accuracy). We run extensive experiments to evaluate ACPL on two public medical image classification benchmarks: Chest X-Ray14 for thorax disease multi-label classification and ISIC2018 for skin lesion multi-class classification. Our method outperforms previous SOTA SSL methods on both datasets

preprint2022arXiv

Contrastive Transformer-based Multiple Instance Learning for Weakly Supervised Polyp Frame Detection

Current polyp detection methods from colonoscopy videos use exclusively normal (i.e., healthy) training images, which i) ignore the importance of temporal information in consecutive video frames, and ii) lack knowledge about the polyps. Consequently, they often have high detection errors, especially on challenging polyp cases (e.g., small, flat, or partially visible polyps). In this work, we formulate polyp detection as a weakly-supervised anomaly detection task that uses video-level labelled training data to detect frame-level polyps. In particular, we propose a novel convolutional transformer-based multiple instance learning method designed to identify abnormal frames (i.e., frames with polyps) from anomalous videos (i.e., videos containing at least one frame with polyp). In our method, local and global temporal dependencies are seamlessly captured while we simultaneously optimise video and snippet-level anomaly scores. A contrastive snippet mining method is also proposed to enable an effective modelling of the challenging polyp cases. The resulting method achieves a detection accuracy that is substantially better than current state-of-the-art approaches on a new large-scale colonoscopy video dataset introduced in this work.

preprint2022arXiv

Deep One-Class Classification via Interpolated Gaussian Descriptor

One-class classification (OCC) aims to learn an effective data description to enclose all normal training samples and detect anomalies based on the deviation from the data description. Current state-of-the-art OCC models learn a compact normality description by hyper-sphere minimisation, but they often suffer from overfitting the training data, especially when the training set is small or contaminated with anomalous samples. To address this issue, we introduce the interpolated Gaussian descriptor (IGD) method, a novel OCC model that learns a one-class Gaussian anomaly classifier trained with adversarially interpolated training samples. The Gaussian anomaly classifier differentiates the training samples based on their distance to the Gaussian centre and the standard deviation of these distances, offering the model a discriminability w.r.t. the given samples during training. The adversarial interpolation is enforced to consistently learn a smooth Gaussian descriptor, even when the training data is small or contaminated with anomalous samples. This enables our model to learn the data description based on the representative normal samples rather than fringe or anomalous samples, resulting in significantly improved normality description. In extensive experiments on diverse popular benchmarks, including MNIST, Fashion MNIST, CIFAR10, MVTec AD and two medical datasets, IGD achieves better detection accuracy than current state-of-the-art models. IGD also shows better robustness in problems with small or contaminated training sets. Code is available at https://github.com/tianyu0207/IGD.

preprint2022arXiv

NVUM: Non-Volatile Unbiased Memory for Robust Medical Image Classification

Real-world large-scale medical image analysis (MIA) datasets have three challenges: 1) they contain noisy-labelled samples that affect training convergence and generalisation, 2) they usually have an imbalanced distribution of samples per class, and 3) they normally comprise a multi-label problem, where samples can have multiple diagnoses. Current approaches are commonly trained to solve a subset of those problems, but we are unaware of methods that address the three problems simultaneously. In this paper, we propose a new training module called Non-Volatile Unbiased Memory (NVUM), which non-volatility stores running average of model logits for a new regularization loss on noisy multi-label problem. We further unbias the classification prediction in NVUM update for imbalanced learning problem. We run extensive experiments to evaluate NVUM on new benchmarks proposed by this paper, where training is performed on noisy multi-label imbalanced chest X-ray (CXR) training sets, formed by Chest-Xray14 and CheXpert, and the testing is performed on the clean multi-label CXR datasets OpenI and PadChest. Our method outperforms previous state-of-the-art CXR classifiers and previous methods that can deal with noisy labels on all evaluations. Our code is available at https://github.com/FBLADL/NVUM.

preprint2022arXiv

Perturbed and Strict Mean Teachers for Semi-supervised Semantic Segmentation

Consistency learning using input image, feature, or network perturbations has shown remarkable results in semi-supervised semantic segmentation, but this approach can be seriously affected by inaccurate predictions of unlabelled training images. There are two consequences of these inaccurate predictions: 1) the training based on the "strict" cross-entropy (CE) loss can easily overfit prediction mistakes, leading to confirmation bias; and 2) the perturbations applied to these inaccurate predictions will use potentially erroneous predictions as training signals, degrading consistency learning. In this paper, we address the prediction accuracy problem of consistency learning methods with novel extensions of the mean-teacher (MT) model, which include a new auxiliary teacher, and the replacement of MT's mean square error (MSE) by a stricter confidence-weighted cross-entropy (Conf-CE) loss. The accurate prediction by this model allows us to use a challenging combination of network, input data and feature perturbations to improve the consistency learning generalisation, where the feature perturbations consist of a new adversarial perturbation. Results on public benchmarks show that our approach achieves remarkable improvements over the previous SOTA methods in the field. Our code is available at https://github.com/yyliu01/PS-MT.

preprint2022arXiv

Pixel-wise Energy-biased Abstention Learning for Anomaly Segmentation on Complex Urban Driving Scenes

State-of-the-art (SOTA) anomaly segmentation approaches on complex urban driving scenes explore pixel-wise classification uncertainty learned from outlier exposure, or external reconstruction models. However, previous uncertainty approaches that directly associate high uncertainty to anomaly may sometimes lead to incorrect anomaly predictions, and external reconstruction models tend to be too inefficient for real-time self-driving embedded systems. In this paper, we propose a new anomaly segmentation method, named pixel-wise energy-biased abstention learning (PEBAL), that explores pixel-wise abstention learning (AL) with a model that learns an adaptive pixel-level anomaly class, and an energy-based model (EBM) that learns inlier pixel distribution. More specifically, PEBAL is based on a non-trivial joint training of EBM and AL, where EBM is trained to output high-energy for anomaly pixels (from outlier exposure) and AL is trained such that these high-energy pixels receive adaptive low penalty for being included to the anomaly class. We extensively evaluate PEBAL against the SOTA and show that it achieves the best performance across four benchmarks. Code is available at https://github.com/tianyu0207/PEBAL.

preprint2022arXiv

Uncertainty-aware Multi-modal Learning via Cross-modal Random Network Prediction

Multi-modal learning focuses on training models by equally combining multiple input data modalities during the prediction process. However, this equal combination can be detrimental to the prediction accuracy because different modalities are usually accompanied by varying levels of uncertainty. Using such uncertainty to combine modalities has been studied by a couple of approaches, but with limited success because these approaches are either designed to deal with specific classification or segmentation problems and cannot be easily translated into other tasks, or suffer from numerical instabilities. In this paper, we propose a new Uncertainty-aware Multi-modal Learner that estimates uncertainty by measuring feature density via Cross-modal Random Network Prediction (CRNP). CRNP is designed to require little adaptation to translate between different prediction tasks, while having a stable training process. From a technical point of view, CRNP is the first approach to explore random network prediction to estimate uncertainty and to combine multi-modal data. Experiments on two 3D multi-modal medical image segmentation tasks and three 2D multi-modal computer vision classification tasks show the effectiveness, adaptability and robustness of CRNP. Also, we provide an extensive discussion on different fusion functions and visualization to validate the proposed model.