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Yuan Liu

Yuan Liu contributes to research discovery and scholarly infrastructure.

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Published work

10 published item(s)

preprint2026arXiv

An AI-guided mechanotyping instrument for fully automated oocyte quality assessment

The mechanical properties of oocytes are regarded as important indicators of their developmental potential. During fertilization, deviations from the normal mechanical range can hinder sperm penetration, ultimately reducing fertilization efficiency and compromising embryo quality. However, current methods for measuring oocyte mechanics often suffer from serious cellular damage, low automation levels, and large measurement errors. To address these limitations, we developed an AI-guided micronewton-scale mechanical measurement system for safe and automated oocyte quality assessment. The system integrates voice interaction with automated experimental workflows to control a magnetically actuated microgripper, which applies defined loading forces to induce micron-scale compressive deformation of the oocyte. Combined with AI-assisted object detection and image segmentation algorithms, the system captures cellular deformation in real time, enabling precise calculation of the oocyte's compressive modulus. This measurement system enables automated, quantitative, and non-destructive evaluation of oocyte mechanical properties, providing an effective approach for oocyte quality screening in in vitro fertilization (IVF) and other assisted reproductive technologies (ART).

preprint2026arXiv

COMPAS: A Distributed Multi-Party SWAP Test for Parallel Quantum Algorithms

The limited number of qubits per chip remains a critical bottleneck in quantum computing, motivating the use of distributed architectures that interconnect multiple quantum processing units (QPUs). However, executing quantum algorithms across distributed systems requires careful co-design of algorithmic primitives and hardware architectures to manage circuit depth and entanglement overhead. We identify multivariate trace estimation as a key subroutine that is naturally suited for distribution, and broadly useful in tasks such as estimating Rényi entropies, virtual cooling and distillation, and certain applications of quantum signal processing. In this work, we introduce COMPAS, an architecture that realizes multivariate trace estimation across a multi-party network of interconnected modular and distributed QPUs by leveraging pre-shared entangled Bell pairs as resources. COMPAS adds only a constant depth overhead and consumes Bell pairs at a rate linear in circuit width, making it suitable for near-term hardware. Unlike other schemes, which must choose between asymptotic optimality in circuit depth or GHZ width, COMPAS achieves both at once. Additionally, we analyze network-level errors and simulate the effects of circuit-level noise on the architecture.

preprint2026arXiv

Distributed Integrated Sensing, Localization, and Communications over LEO Satellite Constellations

Low Earth orbit (LEO) satellite constellations are rapidly becoming essential enablers of next-generation wireless systems, offering global broadband access, high-precision localization, and reliable sensing beyond terrestrial coverage. However, the inherent limitations of individual LEO satellites, including restricted power, limited antenna aperture, and constrained onboard processing, hinder their ability to meet the growing demands of 6G applications. To address these challenges, this article introduces the concept of distributed integrated sensing, localization, and communication (DISLAC) over LEO constellations, inspired by distributed multiple input multiple output architectures. By enabling inter-satellite cooperation through inter-satellite links, DISLAC jointly exploits communication, localization, and sensing functionalities, achieving synergistic gains in throughput, positioning accuracy, and sensing robustness through shared resources and cooperative design. We present illustrative case studies that quantify these benefits and analyze key system-level considerations, including synchronization, antenna reconfigurability, and inter-satellite link design. The article concludes by outlining open research directions to advance the practical deployment of DISLAC in future non-terrestrial networks.

preprint2026arXiv

EgoReAct: Egocentric Video-Driven 3D Human Reaction Generation

Humans exhibit adaptive, context-sensitive responses to egocentric visual input. However, faithfully modeling such reactions from egocentric video remains challenging due to the dual requirements of strictly causal generation and precise 3D spatial alignment. To tackle this problem, we first construct the Human Reaction Dataset (HRD) to address data scarcity and misalignment by building a spatially aligned egocentric video-reaction dataset, as existing datasets (e.g., ViMo) suffer from significant spatial inconsistency between the egocentric video and reaction motion, e.g., dynamically moving motions are always paired with fixed-camera videos. Leveraging HRD, we present EgoReAct, the first autoregressive framework that generates 3D-aligned human reaction motions from egocentric video streams in real-time. We first compress the reaction motion into a compact yet expressive latent space via a Vector Quantised-Variational AutoEncoder and then train a Generative Pre-trained Transformer for reaction generation from the visual input. EgoReAct incorporates 3D dynamic features, i.e., metric depth, and head dynamics during the generation, which effectively enhance spatial grounding. Extensive experiments demonstrate that EgoReAct achieves remarkably higher realism, spatial consistency, and generation efficiency compared with prior methods, while maintaining strict causality during generation. We will release code, models, and data upon acceptance.

preprint2026arXiv

OpenCompass: A Universal Evaluation Platform for Large Language Models

In recent years, the field of artificial intelligence has undergone a paradigm shift from task-specific small-scale models to general-purpose large language models (LLMs). With the rapid iteration of LLMs, objective, quantitative, and comprehensive evaluation of their capabilities has become a critical link in advancing technological development. Currently, the mainstream static benchmark dataset-based evaluation methods face challenges such as the diversity of task types, inconsistent evaluation criteria, and fragmentation of data and processing workflows, making it difficult to efficiently conduct cross-domain and large-scale model evaluation. To address the aforementioned issues, this paper proposes and open-sources OpenCompass, a one-stop, scalable, and high-concurrency-supported general-purpose LLM evaluation platform. Adhering to the design philosophy of modularization and component decoupling, the platform boasts three core advantages: high compatibility, flexibility, and high concurrency. The core architecture of OpenCompass comprises five key components: the Configuration System, Task Partitioning Module, Execution and Scheduling Module, Task Execution Unit, and Result Visualization Module. Its workflow provides rule-based, LLM-as-a-Judge, and cascaded evaluators to adapt to the requirements of different task scenarios. Supporting mainstream benchmark datasets across multiple domains, including knowledge, reasoning, computation, science, language, code, etc., the platform offers a unified and efficient LLM evaluation tool for both academia and industry, facilitating the accurate identification of strengths and weaknesses of LLMs as well as their subsequent optimization.

preprint2026arXiv

SPATIALGEN: Layout-guided 3D Indoor Scene Generation

Creating high-fidelity 3D models of indoor environments is essential for applications in design, virtual reality, and robotics. However, manual 3D modeling remains time-consuming and labor-intensive. While recent advances in generative AI have enabled automated scene synthesis, existing methods often face challenges in balancing visual quality, diversity, semantic consistency, and user control. A major bottleneck is the lack of a large-scale, high-quality dataset tailored to this task. To address this gap, we introduce a comprehensive synthetic dataset, featuring 12,328 structured annotated scenes with 57,431 rooms, and 4.7M photorealistic 2D renderings. Leveraging this dataset, we present SpatialGen, a novel multi-view multi-modal diffusion model that generates realistic and semantically consistent 3D indoor scenes. Given a 3D layout and a reference image (derived from a text prompt), our model synthesizes appearance (color image), geometry (scene coordinate map), and semantic (semantic segmentation map) from arbitrary viewpoints, while preserving spatial consistency across modalities. SpatialGen consistently generates superior results to previous methods in our experiments. We are open-sourcing our data and models to empower the community and advance the field of indoor scene understanding and generation.

preprint2026arXiv

UniSH: Unifying Scene and Human Reconstruction in a Feed-Forward Pass

We present UniSH, a unified, feed-forward framework for joint metric-scale 3D scene and human reconstruction. A key challenge in this domain is the scarcity of large-scale, annotated real-world data, forcing a reliance on synthetic datasets. This reliance introduces a significant sim-to-real domain gap, leading to poor generalization, low-fidelity human geometry, and poor alignment on in-the-wild videos. To address this, we propose an innovative training paradigm that effectively leverages unlabeled in-the-wild data. Our framework bridges strong, disparate priors from scene reconstruction and HMR, and is trained with two core components: (1) a robust distillation strategy to refine human surface details by distilling high-frequency details from an expert depth model, and (2) a two-stage supervision scheme, which first learns coarse localization on synthetic data, then fine-tunes on real data by directly optimizing the geometric correspondence between the SMPL mesh and the human point cloud. This approach enables our feed-forward model to jointly recover high-fidelity scene geometry, human point clouds, camera parameters, and coherent, metric-scale SMPL bodies, all in a single forward pass. Extensive experiments demonstrate that our model achieves state-of-the-art performance on human-centric scene reconstruction and delivers highly competitive results on global human motion estimation, comparing favorably against both optimization-based frameworks and HMR-only methods. Project page: https://murphylmf.github.io/UniSH/

preprint2025arXiv

Co-Designing Spectral Transformation Oracles with Hybrid Oscillator-Qubit Quantum Processors: From Algorithms to Compilation

We co-design a family of quantum eigenvalue transformation oracles that can be efficiently implemented on hybrid discrete/continuous-variable (qubit/qumode) hardware. To illustrate the oracle's representation-theoretic power and near-term experimental accessibility, we encode a Gaussian imaginary time evolution spectral filter. As a result, we define a continuous linear combination of unitaries block-encoding. Due to the ancillary qumode's infinite-dimensional nature, continuous variable qumodes constitute a powerful compilation tool for encoding continuous spectral functions without discretization errors while minimizing resource requirements. We then focus on the ubiquitous task of preparing eigenstates in quantum spin models. For completeness, we provide an end-to-end compilation which expresses high-level oracles in terms of an experimentally realizable instruction set architecture in both 1D and 2D. Finally, we examine the leading-order effects of physical errors and highlight open research directions. Our algorithms scale linearly with the spatial extent of the target system and are applicable to both near-term and large-scale quantum processors.

preprint2025arXiv

Hybrid Oscillator-Qubit Quantum Processors: Instruction Set Architectures, Abstract Machine Models, and Applications

Quantum computing with discrete variable (DV, qubit) hardware is approaching the large scales necessary for computations beyond the reach of classical computers. However, important use cases such as quantum simulations of physical models containing bosonic modes, and quantum error correction are challenging for DV-only systems. Separately, hardware containing native continuous-variable (CV, oscillator) systems has received attention as an alternative approach, yet the universal control of such systems is non-trivial. In this work, we show that hybrid CV-DV hardware offers a great advantage in meeting these challenges, offering a powerful computational paradigm that inherits the strengths of both DV and CV processors. We provide a pedagogical introduction to CV-DV systems and the multiple abstraction layers needed to produce a full software stack connecting applications to hardware. We present a variety of new hybrid CV-DV compilation techniques, algorithms, and applications, including the extension of quantum signal processing concepts to CV-DV systems and strategies to simulate systems of interacting spins, fermions, and bosons. To facilitate the development of hybrid CV-DV processor systems, we introduce formal Abstract Machine Models and Instruction Set Architectures -- essential abstractions that enable developers to formulate applications, compile algorithms, and explore the potential of current and future hardware for realizing fault-tolerant circuits, modules, and processors. Hybrid CV-DV quantum computations are beginning to be performed in superconducting, trapped ion, and neutral atom platforms, and large-scale experiments are set to be demonstrated in the near future. We present a timely and comprehensive guide to this relatively unexplored yet promising approach to quantum computation and providing an architectural backbone to guide future development.

preprint2025arXiv

WonderHuman: Hallucinating Unseen Parts in Dynamic 3D Human Reconstruction

In this paper, we present WonderHuman to reconstruct dynamic human avatars from a monocular video for high-fidelity novel view synthesis. Previous dynamic human avatar reconstruction methods typically require the input video to have full coverage of the observed human body. However, in daily practice, one typically has access to limited viewpoints, such as monocular front-view videos, making it a cumbersome task for previous methods to reconstruct the unseen parts of the human avatar. To tackle the issue, we present WonderHuman, which leverages 2D generative diffusion model priors to achieve high-quality, photorealistic reconstructions of dynamic human avatars from monocular videos, including accurate rendering of unseen body parts. Our approach introduces a Dual-Space Optimization technique, applying Score Distillation Sampling (SDS) in both canonical and observation spaces to ensure visual consistency and enhance realism in dynamic human reconstruction. Additionally, we present a View Selection strategy and Pose Feature Injection to enforce the consistency between SDS predictions and observed data, ensuring pose-dependent effects and higher fidelity in the reconstructed avatar. In the experiments, our method achieves SOTA performance in producing photorealistic renderings from the given monocular video, particularly for those challenging unseen parts. The project page and source code can be found at https://wyiguanw.github.io/WonderHuman/.