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Yixuan Yuan

Yixuan Yuan contributes to research discovery and scholarly infrastructure.

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Computer Vision Artificial Intelligence eess.IV physics.app-ph physics.optics Software Engineering

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preprint2026arXiv

Claw-Eval-Live: A Live Agent Benchmark for Evolving Real-World Workflows

LLM agents are expected to complete end-to-end units of work across software tools, business services, and local workspaces. Yet many agent benchmarks freeze a curated task set at release time and grade mainly the final response, making it difficult to evaluate agents against evolving workflow demand or verify whether a task was executed. We introduce Claw-Eval-Live, a live benchmark for workflow agents that separates a refreshable signal layer, updated across releases from public workflow-demand signals, from a reproducible, time-stamped release snapshot. Each release is constructed from public workflow-demand signals, with ClawHub Top-500 skills used in the current release, and materialized as controlled tasks with fixed fixtures, services, workspaces, and graders. For grading, Claw-Eval-Live records execution traces, audit logs, service state, and post-run workspace artifacts, using deterministic checks when evidence is sufficient and structured LLM judging only for semantic dimensions. The release contains 105 tasks spanning controlled business services and local workspace repair, and evaluates 13 frontier models under a shared public pass rule. Experiments reveal that reliable workflow automation remains far from solved: the leading model passes only 66.7% of tasks and no model reaches 70%. Failures are structured by task family and execution surface, with HR, management, and multi-system business workflows as persistent bottlenecks and local workspace repair comparatively easier but unsaturated. Leaderboard rank alone is insufficient because models with similar pass rates can diverge in overall completion, and task-level discrimination concentrates in a middle band of tasks. Claw-Eval-Live suggests that workflow-agent evaluation should be grounded twice, in fresh external demand and in verifiable agent action.

preprint2026arXiv

The autoPET3 Challenge: Automated Lesion Segmentation in Whole-Body PET/CT $\unicode{x2013}$ Multitracer Multicenter Generalization

We report the design and results of the third autoPET challenge (MICCAI 2024), which benchmarked automated lesion segmentation in whole-body PET/CT under a compositional generalization setting. Training data comprised 1,014 [18F]-FDG PET/CT studies from the University Hospital Tübingen and 597 [18F]/[68Ga]-PSMA PET/CT studies from the LMU University Hospital Munich, constituting the largest publicly available annotated PSMA PET/CT dataset to date. The held-out test set of 200 studies covered four tracer-center combinations, two of which represented unseen compositional pairings. A complementary data-centric award category isolated the contribution of data handling strategies by restricting participants to a fixed baseline model. Seventeen teams submitted 27 algorithms, predominantly nnU-Net-based 3D networks with PET/CT channel concatenation. The top-ranked algorithm achieved a mean DSC of 0.66, FNV of 3.18 mL, and FPV of 2.78 mL across all four test conditions, improving DSC by 8% and reducing the false-negative volume by 5 mL relative to the provided baseline. Ranking was stable across bootstrap resampling and alternative ranking schemes for the top tier. Beyond the benchmark, we provide an in-depth analysis of segmentation performance at the patient and lesion level. Three main conclusions can be drawn: (1) in-domain multitracer PET/CT segmentation is sufficient and probably approaching reader agreement; (2) compositional generalization to unseen tracer-center combinations remains an open problem mainly driven by systematic volume overestimation; (3) heterogeneity and case difficulty drive performance variation substantially more than the choice of algorithm among top-ranked teams.

preprint2026arXiv

Towards a Virtual Neuroscientist: Autonomous Neuroimaging Analysis via Multi-Agent Collaboration

Transforming neuroimaging data into clinically actionable biomarkers is a knowledge-intensive and labor-intensive process. Standardized workflows such as fMRIPrep have improved robustness and efficiency, but they are statically configured and cannot reason about downstream objectives, deliberate over alternative strategies, or close the loop between intermediate evidence and subsequent decisions in the way a human researcher would. This lack of closed-loop adaptation often leaves domain experts trapped in a cycle of manual trial-and-error to tune parameters and remediate pipeline failures, severely constraining the scalability of clinical biomarker development. To bridge this gap, we introduce NIAgent, a multi-agent system for autonomous end-to-end neuroimaging analysis. Unlike conventional flat tool-calling agents, NIAgent adopts a code-centric execution paradigm where specialist agents collaboratively synthesize and optimize executable programs over composable domain-specific primitives. This design enables robust, long-horizon workflow construction that adapts dynamically to runtime observations. Furthermore, we propose a hierarchical verification framework for autonomous quality control, integrating cohort-level metric screening with agentic visual inspection to drive evidence-grounded workflow remediation. Experiments on ADHD-200 and ADNI demonstrate that NIAgent outperforms standard workflow-based baselines in predictive performance while exhibiting sophisticated agentic behaviors, including strategy exploration and adaptive refinement.

preprint2026arXiv

Unveiling and Bridging the Functional Perception Gap in MLLMs: Atomic Visual Alignment and Hierarchical Evaluation via PET-Bench

While Multimodal Large Language Models (MLLMs) have demonstrated remarkable proficiency in tasks such as abnormality detection and report generation for anatomical modalities, their capability in functional imaging remains largely unexplored. In this work, we identify and quantify a fundamental functional perception gap: the inability of current vision encoders to decode functional tracer biodistribution independent of morphological priors. Identifying Positron Emission Tomography (PET) as the quintessential modality to investigate this disconnect, we introduce PET-Bench, the first large-scale functional imaging benchmark comprising 52,308 hierarchical QA pairs from 9,732 multi-site, multi-tracer PET studies. Extensive evaluation of 19 state-of-the-art MLLMs reveals a critical safety hazard termed the Chain-of-Thought (CoT) hallucination trap. We observe that standard CoT prompting, widely considered to enhance reasoning, paradoxically decouples linguistic generation from visual evidence in PET, producing clinically fluent but factually ungrounded diagnoses. To resolve this, we propose Atomic Visual Alignment (AVA), a simple fine-tuning strategy that enforces the mastery of low-level functional perception prior to high-level diagnostic reasoning. Our results demonstrate that AVA effectively bridges the perception gap, transforming CoT from a source of hallucination into a robust inference tool and improving diagnostic accuracy by up to 14.83%. Code and data are available at https://github.com/yezanting/PET-Bench.

preprint2025arXiv

Exploiting Scale-Variant Attention for Segmenting Small Medical Objects

Early detection and accurate diagnosis can predict the risk of malignant disease transformation, thereby increasing the probability of effective treatment. Identifying mild syndrome with small pathological regions serves as an ominous warning and is fundamental in the early diagnosis of diseases. While deep learning algorithms, particularly convolutional neural networks (CNNs), have shown promise in segmenting medical objects, analyzing small areas in medical images remains challenging. This difficulty arises due to information losses and compression defects from convolution and pooling operations in CNNs, which become more pronounced as the network deepens, especially for small medical objects. To address these challenges, we propose a novel scale-variant attention-based network (SvANet) for accurately segmenting small-scale objects in medical images. The SvANet consists of scale-variant attention, cross-scale guidance, Monte Carlo attention, and vision transformer, which incorporates cross-scale features and alleviates compression artifacts for enhancing the discrimination of small medical objects. Quantitative experimental results demonstrate the superior performance of SvANet, achieving 96.12%, 96.11%, 89.79%, 84.15%, 80.25%, 73.05%, and 72.58% in mean Dice coefficient for segmenting kidney tumors, skin lesions, hepatic tumors, polyps, surgical excision cells, retinal vasculatures, and sperms, which occupy less than 1% of the image areas in KiTS23, ISIC 2018, ATLAS, PolypGen, TissueNet, FIVES, and SpermHealth datasets, respectively.

preprint2024arXiv

Integrated lithium niobate microwave photonic processing engine

Integrated microwave photonics is an intriguing field that leverages integrated photonic technologies for the generation, transmission, and manipulation of microwave signals in chip-scale optical systems. In particular, ultrafast processing and computation of analog electronic signals in the optical domain with high fidelity and low latency could enable a variety of applications such as MWP filters, microwave signal processing, and image recognition. An ideal photonic platform for achieving these integrated MWP processing tasks shall simultaneously offer an efficient, linear and high-speed electro-optic modulation block to faithfully perform microwave-optic conversion at low power, and a low-loss functional photonic network that can be configured for a variety of signal processing tasks, as well as large-scale, low-cost manufacturability to monolithically integrate the two building blocks on the same chip. In this work, we demonstrate such an integrated MWP processing engine based on a thin-film lithium niobate platform capable of performing multi-purpose processing and computation tasks of analog signals up to 92 giga samples per second at CMOS-compatible voltages. We demonstrate high-speed analog computation, i.e., first- and second-order temporal integration and differentiation with computing accuracies up to 98.1 %, and deploy these functions to showcase three proof-of-concept applications, namely, ordinary differential equation solving, ultra-wideband signal generation and high-speed edge detection of images. We further leverage the image edge detector to enable a photonic-assisted image segmentation model that could effectively outline the boundaries of melanoma lesion in medical diagnostic images, achieving orders of magnitude faster processing speed and lower power consumption than conventional electronic processors.

preprint2022arXiv

Image Super-resolution with An Enhanced Group Convolutional Neural Network

CNNs with strong learning abilities are widely chosen to resolve super-resolution problem. However, CNNs depend on deeper network architectures to improve performance of image super-resolution, which may increase computational cost in general. In this paper, we present an enhanced super-resolution group CNN (ESRGCNN) with a shallow architecture by fully fusing deep and wide channel features to extract more accurate low-frequency information in terms of correlations of different channels in single image super-resolution (SISR). Also, a signal enhancement operation in the ESRGCNN is useful to inherit more long-distance contextual information for resolving long-term dependency. An adaptive up-sampling operation is gathered into a CNN to obtain an image super-resolution model with low-resolution images of different sizes. Extensive experiments report that our ESRGCNN surpasses the state-of-the-arts in terms of SISR performance, complexity, execution speed, image quality evaluation and visual effect in SISR. Code is found at https://github.com/hellloxiaotian/ESRGCNN.

preprint2022arXiv

Incremental Cross-view Mutual Distillation for Self-supervised Medical CT Synthesis

Due to the constraints of the imaging device and high cost in operation time, computer tomography (CT) scans are usually acquired with low intra-slice resolution. Improving the intra-slice resolution is beneficial to the disease diagnosis for both human experts and computer-aided systems. To this end, this paper builds a novel medical slice synthesis to increase the between-slice resolution. Considering that the ground-truth intermediate medical slices are always absent in clinical practice, we introduce the incremental cross-view mutual distillation strategy to accomplish this task in the self-supervised learning manner. Specifically, we model this problem from three different views: slice-wise interpolation from axial view and pixel-wise interpolation from coronal and sagittal views. Under this circumstance, the models learned from different views can distill valuable knowledge to guide the learning processes of each other. We can repeat this process to make the models synthesize intermediate slice data with increasing inter-slice resolution. To demonstrate the effectiveness of the proposed approach, we conduct comprehensive experiments on a large-scale CT dataset. Quantitative and qualitative comparison results show that our method outperforms state-of-the-art algorithms by clear margins.

preprint2022arXiv

Joint Class-Affinity Loss Correction for Robust Medical Image Segmentation with Noisy Labels

Noisy labels collected with limited annotation cost prevent medical image segmentation algorithms from learning precise semantic correlations. Previous segmentation arts of learning with noisy labels merely perform a pixel-wise manner to preserve semantics, such as pixel-wise label correction, but neglect the pair-wise manner. In fact, we observe that the pair-wise manner capturing affinity relations between pixels can greatly reduce the label noise rate. Motivated by this observation, we present a novel perspective for noisy mitigation by incorporating both pixel-wise and pair-wise manners, where supervisions are derived from noisy class and affinity labels, respectively. Unifying the pixel-wise and pair-wise manners, we propose a robust Joint Class-Affinity Segmentation (JCAS) framework to combat label noise issues in medical image segmentation. Considering the affinity in pair-wise manner incorporates contextual dependencies, a differentiated affinity reasoning (DAR) module is devised to rectify the pixel-wise segmentation prediction by reasoning about intra-class and inter-class affinity relations. To further enhance the noise resistance, a class-affinity loss correction (CALC) strategy is designed to correct supervision signals via the modeled noise label distributions in class and affinity labels. Meanwhile, CALC strategy interacts the pixel-wise and pair-wise manners through the theoretically derived consistency regularization. Extensive experiments under both synthetic and real-world noisy labels corroborate the efficacy of the proposed JCAS framework with a minimum gap towards the upper bound performance. The source code is available at \url{https://github.com/CityU-AIM-Group/JCAS}.

preprint2022arXiv

SIGMA: Semantic-complete Graph Matching for Domain Adaptive Object Detection

Domain Adaptive Object Detection (DAOD) leverages a labeled domain to learn an object detector generalizing to a novel domain free of annotations. Recent advances align class-conditional distributions by narrowing down cross-domain prototypes (class centers). Though great success,they ignore the significant within-class variance and the domain-mismatched semantics within the training batch, leading to a sub-optimal adaptation. To overcome these challenges, we propose a novel SemantIc-complete Graph MAtching (SIGMA) framework for DAOD, which completes mismatched semantics and reformulates the adaptation with graph matching. Specifically, we design a Graph-embedded Semantic Completion module (GSC) that completes mismatched semantics through generating hallucination graph nodes in missing categories. Then, we establish cross-image graphs to model class-conditional distributions and learn a graph-guided memory bank for better semantic completion in turn. After representing the source and target data as graphs, we reformulate the adaptation as a graph matching problem, i.e., finding well-matched node pairs across graphs to reduce the domain gap, which is solved with a novel Bipartite Graph Matching adaptor (BGM). In a nutshell, we utilize graph nodes to establish semantic-aware node affinity and leverage graph edges as quadratic constraints in a structure-aware matching loss, achieving fine-grained adaptation with a node-to-node graph matching. Extensive experiments verify that SIGMA outperforms existing works significantly. Our code is available at https://github.com/CityU-AIM-Group/SIGMA.

preprint2022arXiv

SimT: Handling Open-set Noise for Domain Adaptive Semantic Segmentation

This paper studies a practical domain adaptive (DA) semantic segmentation problem where only pseudo-labeled target data is accessible through a black-box model. Due to the domain gap and label shift between two domains, pseudo-labeled target data contains mixed closed-set and open-set label noises. In this paper, we propose a simplex noise transition matrix (SimT) to model the mixed noise distributions in DA semantic segmentation and formulate the problem as estimation of SimT. By exploiting computational geometry analysis and properties of segmentation, we design three complementary regularizers, i.e. volume regularization, anchor guidance, convex guarantee, to approximate the true SimT. Specifically, volume regularization minimizes the volume of simplex formed by rows of the non-square SimT, which ensures outputs of segmentation model to fit into the ground truth label distribution. To compensate for the lack of open-set knowledge, anchor guidance and convex guarantee are devised to facilitate the modeling of open-set noise distribution and enhance the discriminative feature learning among closed-set and open-set classes. The estimated SimT is further utilized to correct noise issues in pseudo labels and promote the generalization ability of segmentation model on target domain data. Extensive experimental results demonstrate that the proposed SimT can be flexibly plugged into existing DA methods to boost the performance. The source code is available at https://github.com/CityU-AIM-Group/SimT.

preprint2022arXiv

Towards Robust Adaptive Object Detection under Noisy Annotations

Domain Adaptive Object Detection (DAOD) models a joint distribution of images and labels from an annotated source domain and learns a domain-invariant transformation to estimate the target labels with the given target domain images. Existing methods assume that the source domain labels are completely clean, yet large-scale datasets often contain error-prone annotations due to instance ambiguity, which may lead to a biased source distribution and severely degrade the performance of the domain adaptive detector de facto. In this paper, we represent the first effort to formulate noisy DAOD and propose a Noise Latent Transferability Exploration (NLTE) framework to address this issue. It is featured with 1) Potential Instance Mining (PIM), which leverages eligible proposals to recapture the miss-annotated instances from the background; 2) Morphable Graph Relation Module (MGRM), which models the adaptation feasibility and transition probability of noisy samples with relation matrices; 3) Entropy-Aware Gradient Reconcilement (EAGR), which incorporates the semantic information into the discrimination process and enforces the gradients provided by noisy and clean samples to be consistent towards learning domain-invariant representations. A thorough evaluation on benchmark DAOD datasets with noisy source annotations validates the effectiveness of NLTE. In particular, NLTE improves the mAP by 8.4\% under 60\% corrupted annotations and even approaches the ideal upper bound of training on a clean source dataset.

preprint2021arXiv

MetaCorrection: Domain-aware Meta Loss Correction for Unsupervised Domain Adaptation in Semantic Segmentation

Unsupervised domain adaptation (UDA) aims to transfer the knowledge from the labeled source domain to the unlabeled target domain. Existing self-training based UDA approaches assign pseudo labels for target data and treat them as ground truth labels to fully leverage unlabeled target data for model adaptation. However, the generated pseudo labels from the model optimized on the source domain inevitably contain noise due to the domain gap. To tackle this issue, we advance a MetaCorrection framework, where a Domain-aware Meta-learning strategy is devised to benefit Loss Correction (DMLC) for UDA semantic segmentation. In particular, we model the noise distribution of pseudo labels in target domain by introducing a noise transition matrix (NTM) and construct meta data set with domain-invariant source data to guide the estimation of NTM. Through the risk minimization on the meta data set, the optimized NTM thus can correct the noisy issues in pseudo labels and enhance the generalization ability of the model on the target data. Considering the capacity gap between shallow and deep features, we further employ the proposed DMLC strategy to provide matched and compatible supervision signals for different level features, thereby ensuring deep adaptation. Extensive experimental results highlight the effectiveness of our method against existing state-of-the-art methods on three benchmarks.

preprint2020arXiv

Complementary Network with Adaptive Receptive Fields for Melanoma Segmentation

Automatic melanoma segmentation in dermoscopic images is essential in computer-aided diagnosis of skin cancer. Existing methods may suffer from the hole and shrink problems with limited segmentation performance. To tackle these issues, we propose a novel complementary network with adaptive receptive filed learning. Instead of regarding the segmentation task independently, we introduce a foreground network to detect melanoma lesions and a background network to mask non-melanoma regions. Moreover, we propose adaptive atrous convolution (AAC) and knowledge aggregation module (KAM) to fill holes and alleviate the shrink problems. AAC explicitly controls the receptive field at multiple scales and KAM convolves shallow feature maps by dilated convolutions with adaptive receptive fields, which are adjusted according to deep feature maps. In addition, a novel mutual loss is proposed to utilize the dependency between the foreground and background networks, thereby enabling the reciprocally influence within these two networks. Consequently, this mutual training strategy enables the semi-supervised learning and improve the boundary-sensitivity. Training with Skin Imaging Collaboration (ISIC) 2018 skin lesion segmentation dataset, our method achieves a dice co-efficient of 86.4% and shows better performance compared with state-of-the-art melanoma segmentation methods.

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