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Yixuan Sun

Yixuan Sun contributes to research discovery and scholarly infrastructure.

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Published work

9 published item(s)

preprint2026arXiv

Beyond Instance-Level Self-Supervision in 3D Multi-Modal Medical Imaging

Self-supervised pre-training methods in medical imaging typically treat each individual as an isolated instance, learning representations through augmentation-based objectives or masked reconstruction. They often do not adequately capitalize on a key characteristic of physiological features: anatomical structures maintain consistent spatial relationships across individuals (instances), such as the thalamus being medial to the basal ganglia, regardless of variations in brain size, shape, or pathology. We propose leveraging this cross-instance topological consistency as a supervisory signal. The challenge arises from the inherent variability in medical imaging, which can differ significantly across instances and modalities. To tackle this, we focus on two alignment regimes. (i) Intra-instance: with pixel-level correspondences available, a cross-modal triplet objective explicitly preserves local neighborhood topology. (ii) Inter-instance: without such supervision, we derive pseudo-correspondences to control partial neighborhood alignment and prevent topology collapse across modalities. We validate our approach across 7 downstream multi-modal tasks, achieving average improvements of 1.1% and 5.94% in segmentation and classification tasks, respectively, and demonstrating significantly better robustness when modalities are missing at test time.

preprint2025arXiv

Tracing the Heart's Pathways: ECG Representation Learning from a Cardiac Conduction Perspective

The multi-lead electrocardiogram (ECG) stands as a cornerstone of cardiac diagnosis. Recent strides in electrocardiogram self-supervised learning (eSSL) have brightened prospects for enhancing representation learning without relying on high-quality annotations. Yet earlier eSSL methods suffer a key limitation: they focus on consistent patterns across leads and beats, overlooking the inherent differences in heartbeats rooted in cardiac conduction processes, while subtle but significant variations carry unique physiological signatures. Moreover, representation learning for ECG analysis should align with ECG diagnostic guidelines, which progress from individual heartbeats to single leads and ultimately to lead combinations. This sequential logic, however, is often neglected when applying pre-trained models to downstream tasks. To address these gaps, we propose CLEAR-HUG, a two-stage framework designed to capture subtle variations in cardiac conduction across leads while adhering to ECG diagnostic guidelines. In the first stage, we introduce an eSSL model termed Conduction-LEAd Reconstructor (CLEAR), which captures both specific variations and general commonalities across heartbeats. Treating each heartbeat as a distinct entity, CLEAR employs a simple yet effective sparse attention mechanism to reconstruct signals without interference from other heartbeats. In the second stage, we implement a Hierarchical lead-Unified Group head (HUG) for disease diagnosis, mirroring clinical workflow. Experimental results across six tasks show a 6.84% improvement, validating the effectiveness of CLEAR-HUG. This highlights its ability to enhance representations of cardiac conduction and align patterns with expert diagnostic guidelines.

preprint2022arXiv

A data-centric weak supervised learning for highway traffic incident detection

Using the data from loop detector sensors for near-real-time detection of traffic incidents in highways is crucial to averting major traffic congestion. While recent supervised machine learning methods offer solutions to incident detection by leveraging human-labeled incident data, the false alarm rate is often too high to be used in practice. Specifically, the inconsistency in the human labeling of the incidents significantly affects the performance of supervised learning models. To that end, we focus on a data-centric approach to improve the accuracy and reduce the false alarm rate of traffic incident detection on highways. We develop a weak supervised learning workflow to generate high-quality training labels for the incident data without the ground truth labels, and we use those generated labels in the supervised learning setup for final detection. This approach comprises three stages. First, we introduce a data preprocessing and curation pipeline that processes traffic sensor data to generate high-quality training data through leveraging labeling functions, which can be domain knowledge-related or simple heuristic rules. Second, we evaluate the training data generated by weak supervision using three supervised learning models -- random forest, k-nearest neighbors, and a support vector machine ensemble -- and long short-term memory classifiers. The results show that the accuracy of all of the models improves significantly after using the training data generated by weak supervision. Third, we develop an online real-time incident detection approach that leverages the model ensemble and the uncertainty quantification while detecting incidents. Overall, we show that our proposed weak supervised learning workflow achieves a high incident detection rate (0.90) and low false alarm rate (0.08).

preprint2022arXiv

A Survey of Human-in-the-loop for Machine Learning

Human-in-the-loop aims to train an accurate prediction model with minimum cost by integrating human knowledge and experience. Humans can provide training data for machine learning applications and directly accomplish tasks that are hard for computers in the pipeline with the help of machine-based approaches. In this paper, we survey existing works on human-in-the-loop from a data perspective and classify them into three categories with a progressive relationship: (1) the work of improving model performance from data processing, (2) the work of improving model performance through interventional model training, and (3) the design of the system independent human-in-the-loop. Using the above categorization, we summarize major approaches in the field; along with their technical strengths/ weaknesses, we have simple classification and discussion in natural language processing, computer vision, and others. Besides, we provide some open challenges and opportunities. This survey intends to provide a high-level summarization for human-in-the-loop and motivates interested readers to consider approaches for designing effective human-in-the-loop solutions.

preprint2022arXiv

A Systematic Review on Affective Computing: Emotion Models, Databases, and Recent Advances

Affective computing plays a key role in human-computer interactions, entertainment, teaching, safe driving, and multimedia integration. Major breakthroughs have been made recently in the areas of affective computing (i.e., emotion recognition and sentiment analysis). Affective computing is realized based on unimodal or multimodal data, primarily consisting of physical information (e.g., textual, audio, and visual data) and physiological signals (e.g., EEG and ECG signals). Physical-based affect recognition caters to more researchers due to multiple public databases. However, it is hard to reveal one's inner emotion hidden purposely from facial expressions, audio tones, body gestures, etc. Physiological signals can generate more precise and reliable emotional results; yet, the difficulty in acquiring physiological signals also hinders their practical application. Thus, the fusion of physical information and physiological signals can provide useful features of emotional states and lead to higher accuracy. Instead of focusing on one specific field of affective analysis, we systematically review recent advances in the affective computing, and taxonomize unimodal affect recognition as well as multimodal affective analysis. Firstly, we introduce two typical emotion models followed by commonly used databases for affective computing. Next, we survey and taxonomize state-of-the-art unimodal affect recognition and multimodal affective analysis in terms of their detailed architectures and performances. Finally, we discuss some important aspects on affective computing and their applications and conclude this review with an indication of the most promising future directions, such as the establishment of baseline dataset, fusion strategies for multimodal affective analysis, and unsupervised learning models.

preprint2022arXiv

A Wavelet-CNN-LSTM Model for Tailings Pond Risk Prediction

Tailings ponds are places for storing industrial waste. Once the tailings pond collapses, the villages nearby will be destroyed and the harmful chemicals will cause serious environmental pollution. There is an urgent need for a reliable forecast model, which could investigate the variation trend of stability coefficient of tailing dam and issue early warnings. In order to fill the gap, this work presents an hybrid network - Wavelet-based Long-Short-Term Memory (LSTM) and Convolutional Neural Network (CNN), namely Wavelet-CNN-LSTM netwrok for predicting the tailings pond risk. Firstly, we construct the especial nonlinear data processing method to impute the missing value with the numerical inversion (NI) method, which combines correlation analysis, sensitivity analysis, and Random Forest (RF) algorithms. Secondly, a new forecasting model was proposed to monitor the saturation line, which is the lifeline of the tailings pond and can directly reflect the stability of the tailings pond. After using the discrete wavelet transform (DWT) to decompose the original saturation line data into 4-layer wavelets and de-noise the data, the CNN was used to identify and learn the spatial structures in the time series, followed by LSTM cells for detecting the long-short-term dependence. Finally, different experiments were conducted to evaluate the effectiveness of our model by comparing it with other state-of-the-art algorithms. The results show that Wavelet-CNN-LSTM achieves the best score both in mean absolute percentage error (MAPE), root-mean-square error (RMSE) and R 2 .

preprint2022arXiv

FERV39k: A Large-Scale Multi-Scene Dataset for Facial Expression Recognition in Videos

Current benchmarks for facial expression recognition (FER) mainly focus on static images, while there are limited datasets for FER in videos. It is still ambiguous to evaluate whether performances of existing methods remain satisfactory in real-world application-oriented scenes. For example, the "Happy" expression with high intensity in Talk-Show is more discriminating than the same expression with low intensity in Official-Event. To fill this gap, we build a large-scale multi-scene dataset, coined as FERV39k. We analyze the important ingredients of constructing such a novel dataset in three aspects: (1) multi-scene hierarchy and expression class, (2) generation of candidate video clips, (3) trusted manual labelling process. Based on these guidelines, we select 4 scenarios subdivided into 22 scenes, annotate 86k samples automatically obtained from 4k videos based on the well-designed workflow, and finally build 38,935 video clips labeled with 7 classic expressions. Experiment benchmarks on four kinds of baseline frameworks were also provided and further analysis on their performance across different scenes and some challenges for future research were given. Besides, we systematically investigate key components of DFER by ablation studies. The baseline framework and our project will be available.

preprint2020arXiv

Survey of the Detection and Classification of Pulmonary Lesions via CT and X-Ray

In recent years, the prevalence of several pulmonary diseases, especially the coronavirus disease 2019 (COVID-19) pandemic, has attracted worldwide attention. These diseases can be effectively diagnosed and treated with the help of lung imaging. With the development of deep learning technology and the emergence of many public medical image datasets, the diagnosis of lung diseases via medical imaging has been further improved. This article reviews pulmonary CT and X-ray image detection and classification in the last decade. It also provides an overview of the detection of lung nodules, pneumonia, and other common lung lesions based on the imaging characteristics of various lesions. Furthermore, this review introduces 26 commonly used public medical image datasets, summarizes the latest technology, and discusses current challenges and future research directions.

preprint2019arXiv

Modeling and design optimization for pleated membrane filters

Pleated membrane filters, which offer larger surface area to volume ratios than unpleated membrane filters, are used in a wide variety of applications. However, the performance of the pleated filter, as characterized by a flux-throughput plot, indicates that the equivalent unpleated filter provides better performance under the same pressure drop. Earlier work (Sanaei & Cummings 2016) used a highly-simplified membrane model to investigate how the pleating effect and membrane geometry affect this performance differential. In this work, we extend this line of investigation and use asymptotic methods to couple an outer problem for the flow within the pleated structure to an inner problem that accounts for the pore structure within the membrane. We use our new model to formulate and address questions of optimal membrane design for a given filtration application.