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Yinuo Zhang

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Published work

3 published item(s)

preprint2026arXiv

Direct Detection of Type II-P Supernova Progenitors with the Euclid and CSST Surveys

A central goal in supernova (SN) research is to identify and characterize their progenitors. However, this is very difficult due to the limited archival images with sufficient depth and spatial resolution required for direct progenitor detection and due to the circumstellar dust which often biases the estimate of their intrinsic parameters. This field will be revolutionized by Euclid and the upcoming Chinese Space Station Survey Telescope (CSST), which conduct deep, wide-field, high-resolution and multi-band imaging surveys. We analyze their detection capability by comparing the model magnitudes of red supergiant (RSG) progenitors with the detection limits under different conditions, and we estimate the annual detection rates with Monte-Carlo simulations. We explore how to recover the intrinsic properties of SN progenitors with the help of radiation transfer calculations in circumstellar dust. We find the optical and near-infrared filters of the Euclid and CSST are highly effective for detecting RSG progenitors. We predict that archival images from the completed 2 surveys will enable $\lesssim13$ (or 24) progenitor detections per year within the mass range of 8--16 (or 8--25)M_\odot, an order of magnitude higher than the current detection rate of $\sim1$ detection per year. In the presence of circumstellar dust, the emerging spectral energy distribution (SED) of the progenitor is mainly affected by the optical depth and is almost independent of dust temperature in the Euclid and CSST filters. Our mock tests demonstrate that one can derive the progenitor mass and dust optical depth simultaneously by fitting the observed SED over the 11 filters of the 2 surveys while fixing the dust temperature to a typical value. Euclid and CSST will significantly enlarge the sample of direct progenitor detections with accurate mass measurements, which is crucial to resolve the long-standing RSG problem.

preprint2026arXiv

TD3B: Transition-Directed Discrete Diffusion for Allosteric Binder Generation

Protein function is often controlled by ligands that bias the direction of state transitions, such as agonists and antagonists, rather than stabilizing a single conformation. This is especially important for clinically relevant G protein-coupled receptors (GPCRs), where therapeutic efficacy depends on functional directionality. Structure-based design methods optimize binding to static conformations and cannot represent non-reversible, directional effects or systematically distinguish agonist from antagonist behavior. To address this gap, we introduce Transition-Directed Discrete Diffusion for Allosteric Binder Design (TD3B), a sequence-based generative framework that designs binders with specified agonist or antagonist behavior via a directional transition control objective. TD3B combines a target-aware Direction Oracle, a soft binding-affinity gate, and amortized fine-tuning of a pre-trained discrete diffusion model, enabling targeted agonist and antagonist generation decoupled from binding affinity and unattainable by equilibrium-based or inference-only guidance baselines. The code and checkpoints are available at https://huggingface.co/ChatterjeeLab/TD3B.

preprint2015arXiv

Shifted Hecke insertion and the K-theory of OG(n,2n+1)

Patrias and Pylyavskyy introduced shifted Hecke insertion as an application of their theory of dual filtered graphs. We use shifted Hecke insertion to construct symmetric function representatives for the K-theory of the orthogonal Grassmannian. These representatives are closely related to the shifted Grothendieck polynomials of Ikeda and Naruse. We then recover the K-theory structure coefficients of Clifford-Thomas-Yong/Buch-Samuel by introducing a shifted K-theoretic Poirier-Reutenauer algebra. Our proofs depend on the theory of shifted K-theoretic jeu de taquin and the weak K-Knuth relations.