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Truong-Son Hy

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2 published item(s)

preprint2026arXiv

DiFlow-TTS: Compact and Low-Latency Zero-Shot Text-to-Speech with Factorized Discrete Flow Matching

This paper introduces DiFlow-TTS, a novel zero-shot text-to-speech (TTS) system that employs discrete flow matching for generative speech modeling. We position this work as an entry point that may facilitate further advances in this research direction. Through extensive empirical evaluation, we analyze both the strengths and limitations of this approach across key aspects, including naturalness, expressive attributes, speaker identity, and inference latency. To this end, we leverage factorized speech representations and design a deterministic Phoneme-Content Mapper for modeling linguistic content, together with a Factorized Discrete Flow Denoiser that jointly models multiple discrete token streams corresponding to prosody and acoustics to capture expressive speech attributes. Experimental results demonstrate that DiFlow-TTS achieves strong performance across multiple metrics while maintaining a compact model size, up to 11.7 times smaller, and enabling low-latency inference that is up to 34 times faster than recent state-of-the-art baselines. Audio samples are available on our demo page: https://diflow-tts.github.io.

preprint2026arXiv

PRIME: Protein Representation via Physics-Informed Multiscale Equivariant Hierarchies

Proteins are inherently multiscale physical systems whose functional properties emerge from coordinated structural organization across multiple spatial resolutions, ranging from atomic interactions to global fold topology. However, existing protein representation learning methods typically operate at a single structural level or treat different sources of structural information as parallel modalities, without explicitly modeling their hierarchical relationships. We introduce PRIME (Protein Representation via Physics-Informed Multiscale Equivariant Hierarchies), a unified framework that models proteins as a nested family of five physically grounded structural graphs spanning surface, atomic, residue, secondary-structure, and protein levels. Adjacent levels are connected through deterministic, physics-informed assignment operators, enabling bidirectional information exchange via bottom-up aggregation and top-down contextual refinement. Experiments on standard protein representation learning benchmarks demonstrate strong and competitive performance across diverse tasks, with particularly notable gains on the Fold Classification benchmark, where PRIME outperforms the strongest geometric GNN baseline by margins of 13.80 and 18.30 points on the harder Superfamily and Fold splits, and achieves a state-of-the-art accuracy of 84.10\% on Reaction Class prediction, surpassing all baseline methods, including ESM. Ablation studies confirm that each structural level contributes complementary and non-redundant information, and adaptive cross-attention analysis reveals that PRIME autonomously identifies the most task-relevant structural resolutions at prediction time. Our source code is publicly available at https://github.com/HySonLab/PRIME