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Sitong Wu

Sitong Wu contributes to research discovery and scholarly infrastructure.

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Published work

5 published item(s)

preprint2026arXiv

Efficient Long-Context Modeling in Diffusion Language Models via Block Approximate Sparse Attention

Diffusion Language Models (DLMs) enable globally coherent, bidirectional, and controllable text generation, offering advantages over traditional autoregressive LLMs, while scaling to ultra-long sequences remains costly. Many existing block-sparse attention methods select blocks by fixed sampling patterns over the high-resolution attention space, such as tail regions or anti-diagonal stripes. Such prior-driven sampling can miss salient tokens and introduce instability under distribution shifts. In this paper, we propose the Block Approximate Sparse Attention framework (BA-Att) with block-wise pre-downsampled operation, which identifies informative regions within a compact downsampled space, avoiding reliance on brittle positional priors. To analyze its theoretical behavior, we define an oracle post-downsample attention map and formalize the approximation error between pre- and post-downsample schemes. Based on this insight, we introduce a lightweight norm-sorting module and a covariance-compensated correction that approximates full covariance using diagonal QK variances, reducing computational complexity. Extensive experiments show that our operator achieves up to 6.95x acceleration over FlashAttention in attention computation, and maintains near full-attention performance at 50% sparsity across language models, multimodal language models, and video generation models, demonstrating strong efficiency and generalization.

preprint2023arXiv

Nanoparticles Passive Targeting Allows Optical Imaging of Bone Diseases

Bone health related skeletal disorders are commonly diagnosed by X-ray imaging, but the radiation limits its use. Light excitation and optical imaging through the near-infrared-II window (NIR-II, 1000-1700 nm) can penetrate deep tissues without radiation risk, but the targeting of contrast agent is non-specific. Here, we report that lanthanide-doped nanocrystals can be passively transported by endothelial cells and macrophages from the blood vessels into bone marrow microenvironment. We found that this passive targeting scheme can be effective for longer than two months. We therefore developed an intravital 3D and high-resolution planar imaging instrumentation for bone disease diagnosis. We demonstrated the regular monitoring of 1 mm bone defects for over 10 days, with resolution similar to X-ray imaging result, but more flexible use in prognosis. Moreover, the passive targeting can be used to reveal the early onset inflammation at the joints as the synovitis in the early stage of rheumatoid arthritis. Furthermore, the proposed method is comparable to μCT in recognizing symptoms of osteoarthritis, including the mild hyperostosis in femur which is ~100 μm thicker than normal, and the growth of millimeter-scale osteophyte in the knee joint, which further proves the power and universality of our approach in diagnosis of bone diseases

preprint2022arXiv

CATrans: Context and Affinity Transformer for Few-Shot Segmentation

Few-shot segmentation (FSS) aims to segment novel categories given scarce annotated support images. The crux of FSS is how to aggregate dense correlations between support and query images for query segmentation while being robust to the large variations in appearance and context. To this end, previous Transformer-based methods explore global consensus either on context similarity or affinity map between support-query pairs. In this work, we effectively integrate the context and affinity information via the proposed novel Context and Affinity Transformer (CATrans) in a hierarchical architecture. Specifically, the Relation-guided Context Transformer (RCT) propagates context information from support to query images conditioned on more informative support features. Based on the observation that a huge feature distinction between support and query pairs brings barriers for context knowledge transfer, the Relation-guided Affinity Transformer (RAT) measures attention-aware affinity as auxiliary information for FSS, in which the self-affinity is responsible for more reliable cross-affinity. We conduct experiments to demonstrate the effectiveness of the proposed model, outperforming the state-of-the-art methods.

preprint2022arXiv

Feature Selective Transformer for Semantic Image Segmentation

Recently, it has attracted more and more attentions to fuse multi-scale features for semantic image segmentation. Various works were proposed to employ progressive local or global fusion, but the feature fusions are not rich enough for modeling multi-scale context features. In this work, we focus on fusing multi-scale features from Transformer-based backbones for semantic segmentation, and propose a Feature Selective Transformer (FeSeFormer), which aggregates features from all scales (or levels) for each query feature. Specifically, we first propose a Scale-level Feature Selection (SFS) module, which can choose an informative subset from the whole multi-scale feature set for each scale, where those features that are important for the current scale (or level) are selected and the redundant are discarded. Furthermore, we propose a Full-scale Feature Fusion (FFF) module, which can adaptively fuse features of all scales for queries. Based on the proposed SFS and FFF modules, we develop a Feature Selective Transformer (FeSeFormer), and evaluate our FeSeFormer on four challenging semantic segmentation benchmarks, including PASCAL Context, ADE20K, COCO-Stuff 10K, and Cityscapes, outperforming the state-of-the-art.

preprint2022arXiv

High Spatial and Temporal Resolution NIR-IIb Gastrointestinal Imaging in Mice

Conventional biomedical imaging modalities, including endoscopy, X-rays, and magnetic resonance, are invasive and cannot provide sufficient spatial and temporal resolutions for regular imaging of gastrointestinal (GI) tract to guide prognosis and therapy of GI diseases. Here we report a non-invasive method for optical imaging of GI tract. It is based on a new type of lanthanide-doped nanocrystal with near-infrared (NIR) excitation at 980 nm and second NIR window (NIR-IIb) (1500~1700 nm) fluorescence emission at around 1530 nm. The rational design and controlled synthesis of nanocrystals with high brightness have led to an absolute quantum yield (QY) up to 48.6%. Further benefitting from the minimized scattering through the NIR-IIb window, we enhanced the spatial resolution by 3 times compared with the other NIR-IIa (1000~1500 nm) contract agents for GI tract imaging. The approach also led to a high temporal resolution of 8 frames per second, so that the moment of mice intestinal peristalsis happened in one minute can be captured. Furthermore, with a light-sheet imaging system, we demonstrated a three-dimensional (3D) imaging of the stereoscopic structure of the GI tract. Moreover, we successfully translate these advances to diagnose inflammatory bowel disease (IBD) in a pre-clinical model of mice colitis.