Researcher profile

Shahriar Noroozizadeh

Shahriar Noroozizadeh contributes to research discovery and scholarly infrastructure.

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Published work

2 published item(s)

preprint2026arXiv

PMOA-TTS: Introducing the PubMed Open Access Textual Times Series Corpus

Clinical narratives encode temporal dynamics essential for modeling patient trajectories, yet large-scale temporally annotated resources are scarce. We introduce PMOA-TTS, a corpus of 124,699 single-patient PubMed Open Access case reports converted into structured textual timelines of (event, time) pairs using a scalable large-language-model pipeline (Llama 3.3 70B and DeepSeek-R1). The corpus comprises over 5.6 million timestamped events, alongside extracted demographics and diagnoses. Technical validation uses a clinician-curated gold set and three measures: semantic event matching, temporal concordance (c-index), and alignment error summarized with Area Under the Log-Time CDF (AULTC). We benchmark alternative prompting and model choices and provide documentation to support reproduction. PMOA-TTS enables research on timeline extraction, temporal reasoning, survival modeling and event forecasting from narrative text, and offers broad diagnostic and demographic coverage. Data and code are openly available in public repositories.

preprint2026arXiv

Text Knows What, Tables Know When: Clinical Timeline Reconstruction via Retrieval-Augmented Multimodal Alignment

Reconstructing precise clinical timelines is essential for modeling patient trajectories and forecasting risk in complex, heterogeneous conditions like sepsis. While unstructured clinical narratives offer semantically rich and contextually complete descriptions of a patient's course, they often lack temporal precision and contain ambiguous event timing. Conversely, structured electronic health record (EHR) data provides precise temporal anchors but misses a substantial portion of clinically meaningful events. We introduce a retrieval-augmented multimodal alignment framework that bridges this gap to improve the temporal precision of absolute clinical timelines extracted from text. Our approach formulates timeline reconstruction as a graph-based multistep process: it first extracts central anchor events from narratives to build an initial temporal scaffold, places non-central events relative to this backbone, and then calibrates the timeline using retrieved structured EHR rows as external temporal evidence. Evaluated using instruction-tuned large language models on the i2m4 benchmark spanning MIMIC-III and MIMIC-IV, our multimodal pipeline consistently improves absolute timestamp accuracy (AULTC) and improves temporal concordance across nearly all evaluated models over unimodal text-only reconstruction, without compromising event match rates. Furthermore, our empirical gap analysis reveals that 34.8% of text-derived events are entirely absent from tabular records, demonstrating that aligning these modalities can produce a more temporally faithful and clinically informative reconstruction of patient trajectories than either source alone.