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Researcher profile

Sebastian Lapuschkin

Sebastian Lapuschkin contributes to research discovery and scholarly infrastructure.

ResearcherAffiliation not importedOpen to collaborate
Machine LearningComputer VisionArtificial Intelligenceeess.IVNeural and Evolutionary ComputingQuantitative Methods

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Published work

9 published item(s)

preprint2026arXiv

Playing the network backward: A Game Theoretic Attribution Framework

Attribution methods explain which input features drive a model's prediction, making them central to model debugging and mechanistic interpretability. Yet backward attribution methods, including gradients, LRP, and transformer-specific rules, lack a shared framework in which to compare the underlying backward calculations. We introduce such a framework by recasting backward attribution as a two-player game on an extended network graph, building on Gaubert and Vlassopoulos' ReLU Net Game. Gradients and the full alpha-beta-LRP family arise as integrals over game trajectories under specific equilibria, so attribution maps become projections of trajectory distributions rather than the primary object. Desired explanation properties, such as localisation focus, robustness to input noise, or stable attention routing, can be specified as game-theoretic concepts, including policy regularization, risk aversion, and extended action sets, and translate directly into novel adaptations of the well-known backward rules. On ViT-B/16, one such selected adaptation of alpha-beta-LRP outperforms prior transformer-specific backward methods across all considered localisation metrics.

0 citations0 reviewsNo code linkedOpen access
preprint2024arXiv

From Attribution Maps to Human-Understandable Explanations through Concept Relevance Propagation

The field of eXplainable Artificial Intelligence (XAI) aims to bring transparency to today's powerful but opaque deep learning models. While local XAI methods explain individual predictions in form of attribution maps, thereby identifying where important features occur (but not providing information about what they represent), global explanation techniques visualize what concepts a model has generally learned to encode. Both types of methods thus only provide partial insights and leave the burden of interpreting the model's reasoning to the user. In this work we introduce the Concept Relevance Propagation (CRP) approach, which combines the local and global perspectives and thus allows answering both the "where" and "what" questions for individual predictions. We demonstrate the capability of our method in various settings, showcasing that CRP leads to more human interpretable explanations and provides deep insights into the model's representation and reasoning through concept atlases, concept composition analyses, and quantitative investigations of concept subspaces and their role in fine-grained decision making.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Beyond Explaining: Opportunities and Challenges of XAI-Based Model Improvement

Explainable Artificial Intelligence (XAI) is an emerging research field bringing transparency to highly complex and opaque machine learning (ML) models. Despite the development of a multitude of methods to explain the decisions of black-box classifiers in recent years, these tools are seldomly used beyond visualization purposes. Only recently, researchers have started to employ explanations in practice to actually improve models. This paper offers a comprehensive overview over techniques that apply XAI practically for improving various properties of ML models, and systematically categorizes these approaches, comparing their respective strengths and weaknesses. We provide a theoretical perspective on these methods, and show empirically through experiments on toy and realistic settings how explanations can help improve properties such as model generalization ability or reasoning, among others. We further discuss potential caveats and drawbacks of these methods. We conclude that while model improvement based on XAI can have significant beneficial effects even on complex and not easily quantifyable model properties, these methods need to be applied carefully, since their success can vary depending on a multitude of factors, such as the model and dataset used, or the employed explanation method.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Explain to Not Forget: Defending Against Catastrophic Forgetting with XAI

The ability to continuously process and retain new information like we do naturally as humans is a feat that is highly sought after when training neural networks. Unfortunately, the traditional optimization algorithms often require large amounts of data available during training time and updates wrt. new data are difficult after the training process has been completed. In fact, when new data or tasks arise, previous progress may be lost as neural networks are prone to catastrophic forgetting. Catastrophic forgetting describes the phenomenon when a neural network completely forgets previous knowledge when given new information. We propose a novel training algorithm called training by explaining in which we leverage Layer-wise Relevance Propagation in order to retain the information a neural network has already learned in previous tasks when training on new data. The method is evaluated on a range of benchmark datasets as well as more complex data. Our method not only successfully retains the knowledge of old tasks within the neural networks but does so more resource-efficiently than other state-of-the-art solutions.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Measurably Stronger Explanation Reliability via Model Canonization

While rule-based attribution methods have proven useful for providing local explanations for Deep Neural Networks, explaining modern and more varied network architectures yields new challenges in generating trustworthy explanations, since the established rule sets might not be sufficient or applicable to novel network structures. As an elegant solution to the above issue, network canonization has recently been introduced. This procedure leverages the implementation-dependency of rule-based attributions and restructures a model into a functionally identical equivalent of alternative design to which established attribution rules can be applied. However, the idea of canonization and its usefulness have so far only been explored qualitatively. In this work, we quantitatively verify the beneficial effects of network canonization to rule-based attributions on VGG-16 and ResNet18 models with BatchNorm layers and thus extend the current best practices for obtaining reliable neural network explanations.

0 citations0 reviewsNo code linkedOpen access
preprint2021arXiv

Explaining Deep Neural Networks and Beyond: A Review of Methods and Applications

With the broader and highly successful usage of machine learning in industry and the sciences, there has been a growing demand for Explainable AI. Interpretability and explanation methods for gaining a better understanding about the problem solving abilities and strategies of nonlinear Machine Learning, in particular, deep neural networks, are therefore receiving increased attention. In this work we aim to (1) provide a timely overview of this active emerging field, with a focus on 'post-hoc' explanations, and explain its theoretical foundations, (2) put interpretability algorithms to a test both from a theory and comparative evaluation perspective using extensive simulations, (3) outline best practice aspects i.e. how to best include interpretation methods into the standard usage of machine learning and (4) demonstrate successful usage of explainable AI in a representative selection of application scenarios. Finally, we discuss challenges and possible future directions of this exciting foundational field of machine learning.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

On the Explanation of Machine Learning Predictions in Clinical Gait Analysis

Machine learning (ML) is increasingly used to support decision-making in the healthcare sector. While ML approaches provide promising results with regard to their classification performance, most share a central limitation, namely their black-box character. Motivated by the interest to understand the functioning of ML models, methods from the field of Explainable Artificial Intelligence (XAI) have recently become important. This article investigates the usefulness of XAI methods in clinical gait classification. For this purpose, predictions of state-of-the-art classification methods are explained with an established XAI method, i.e., Layer-wise Relevance Propagation (LRP). We propose to evaluate the obtained explanations with two complementary approaches: a statistical analysis of the underlying data using Statistical Parametric Mapping and a qualitative evaluation by a clinical expert. A gait dataset comprising ground reaction force measurements from 132 patients with different lower-body gait disorders and 62 healthy controls is utilized. We investigate several gait classification tasks, employ multiple classification methods, and analyze the impact of data normalization and different signal components for classification performance and explanation quality. Our experiments show that explanations obtained by LRP exhibit promising statistical properties concerning inter-class discriminativity and are also in line with clinically relevant biomechanical gait characteristics.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Resolving challenges in deep learning-based analyses of histopathological images using explanation methods

Deep learning has recently gained popularity in digital pathology due to its high prediction quality. However, the medical domain requires explanation and insight for a better understanding beyond standard quantitative performance evaluation. Recently, explanation methods have emerged, which are so far still rarely used in medicine. This work shows their application to generate heatmaps that allow to resolve common challenges encountered in deep learning-based digital histopathology analyses. These challenges comprise biases typically inherent to histopathology data. We study binary classification tasks of tumor tissue discrimination in publicly available haematoxylin and eosin slides of various tumor entities and investigate three types of biases: (1) biases which affect the entire dataset, (2) biases which are by chance correlated with class labels and (3) sampling biases. While standard analyses focus on patch-level evaluation, we advocate pixel-wise heatmaps, which offer a more precise and versatile diagnostic instrument and furthermore help to reveal biases in the data. This insight is shown to not only detect but also to be helpful to remove the effects of common hidden biases, which improves generalization within and across datasets. For example, we could see a trend of improved area under the receiver operating characteristic curve by 5% when reducing a labeling bias. Explanation techniques are thus demonstrated to be a helpful and highly relevant tool for the development and the deployment phases within the life cycle of real-world applications in digital pathology.

0 citations0 reviewsNo code linkedOpen access
preprint2020arXiv

Towards Best Practice in Explaining Neural Network Decisions with LRP

Within the last decade, neural network based predictors have demonstrated impressive - and at times super-human - capabilities. This performance is often paid for with an intransparent prediction process and thus has sparked numerous contributions in the novel field of explainable artificial intelligence (XAI). In this paper, we focus on a popular and widely used method of XAI, the Layer-wise Relevance Propagation (LRP). Since its initial proposition LRP has evolved as a method, and a best practice for applying the method has tacitly emerged, based however on humanly observed evidence alone. In this paper we investigate - and for the first time quantify - the effect of this current best practice on feedforward neural networks in a visual object detection setting. The results verify that the layer-dependent approach to LRP applied in recent literature better represents the model's reasoning, and at the same time increases the object localization and class discriminativity of LRP.

0 citations0 reviewsNo code linkedOpen access