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Ruiyu Wang

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Published work

4 published item(s)

preprint2026arXiv

A Multimodal Pre-trained Network for Integrated EEG-Video Seizure Detection

Reliable seizure detection in mouse models is essential for preclinical epilepsy research, yet manual review of synchronized video-EEG recordings is labor-intensive and single-modality systems fail for complementary reasons: video-based methods are easily confounded by benign behaviors, whereas EEG-based methods are vulnerable to ictal motion artifacts. We present EEGVFusion, a multimodal framework that combines self-supervised EEG representation learning, spatio-temporal video encoding, optimal-transport alignment, and bidirectional cross-attention to integrate neural and behavioral evidence. We also curate an expert-annotated dataset of synchronized EEG and video recordings comprising 93 sessions from 15 mice for training and evaluation. In the random-session split, EEGVFusion achieved a Balanced Accuracy of 0.9957 with perfect event sensitivity and an Event FAR of 0.6250 FP/h, indicating strong seizure detection performance with a low false-alarm burden. In a single held-out-subject evaluation with Subject 110 reserved for testing, EEGVFusion achieved a Balanced Accuracy of 0.9718 and reduced Event FAR from 2.7250 FP/h for the EEG-only counterpart to 0.4833 FP/h while preserving perfect event sensitivity. Targeted ablations further showed that EEG pre-training and OT alignment help reduce false alarms while preserving event sensitivity.

preprint2026arXiv

CADMorph: Geometry-Driven Parametric CAD Editing via a Plan-Generate-Verify Loop

A Computer-Aided Design (CAD) model encodes an object in two coupled forms: a parametric construction sequence and its resulting visible geometric shape. During iterative design, adjustments to the geometric shape inevitably require synchronized edits to the underlying parametric sequence, called geometry-driven parametric CAD editing. The task calls for 1) preserving the original sequence's structure, 2) ensuring each edit's semantic validity, and 3) maintaining high shape fidelity to the target shape, all under scarce editing data triplets. We present CADMorph, an iterative plan-generate-verify framework that orchestrates pretrained domain-specific foundation models during inference: a parameter-to-shape (P2S) latent diffusion model and a masked-parameter-prediction (MPP) model. In the planning stage, cross-attention maps from the P2S model pinpoint the segments that need modification and offer editing masks. The MPP model then infills these masks with semantically valid edits in the generation stage. During verification, the P2S model embeds each candidate sequence in shape-latent space, measures its distance to the target shape, and selects the closest one. The three stages leverage the inherent geometric consciousness and design knowledge in pretrained priors, and thus tackle structure preservation, semantic validity, and shape fidelity respectively. Besides, both P2S and MPP models are trained without triplet data, bypassing the data-scarcity bottleneck. CADMorph surpasses GPT-4o and specialized CAD baselines, and supports downstream applications such as iterative editing and reverse-engineering enhancement.

preprint2026arXiv

Thinking with Blueprints: Assisting Vision-Language Models in Spatial Reasoning via Structured Object Representation

Spatial reasoning -- the ability to perceive and reason about relationships in space -- advances vision-language models (VLMs) from visual perception toward spatial semantic understanding. Existing approaches either revisit local image patches, improving fine-grained perception but weakening global spatial awareness, or mark isolated coordinates, which capture object locations but overlook their overall organization. In this work, we integrate the cognitive concept of an object-centric blueprint into VLMs to enhance spatial reasoning. Given an image and a question, the model first constructs a JSON-style blueprint that records the positions, sizes, and attributes of relevant objects, and then reasons over this structured representation to produce the final answer. To achieve this, we introduce three key techniques: (1) blueprint-embedded reasoning traces for supervised fine-tuning to elicit basic reasoning skills; (2) blueprint-aware rewards in reinforcement learning to encourage the blueprint to include an appropriate number of objects and to align final answers with this causal reasoning; and (3) anti-shortcut data augmentation that applies targeted perturbations to images and questions, discouraging reliance on superficial visual or linguistic cues. Experiments show that our method consistently outperforms existing VLMs and specialized spatial reasoning models.

preprint2023arXiv

Is the Local Ion Density Sufficient to Drive NaCl Nucleation from the Melt and Aqueous Solution?

Even though nucleation is ubiquitous in different science and engineering problems, investigating nucleation is extremely difficult due to the complicated ranges of time and length scales involved. In this work, we simulate NaCl nucleation in both molten and aqueous environments using enhanced sampling all-atom molecular dynamics with deep learning-based estimation of reaction coordinates. By incorporating various structural order parameters and learning the reaction coordinate as a function thereof, we achieve significantly improved sampling relative to traditional ad hoc descriptions of what drives nucleation, particularly in the aqueous medium. Our results reveal a one-step nucleation mechanism in both environments, with reaction coordinate analysis highlighting the importance of local ion density in distinguishing solid and liquid states. However, while fluctuations in the local ion density are necessary to drive nucleation, they are not sufficient. Our analysis shows that near the transition states, descriptors such as enthalpy and local structure become crucial. Our protocol proposed here enables robust nucleation analysis and phase sampling, and could offer insights into nucleation mechanisms for generic small molecules in different environments.