BZPEERReading, trust and collaboration for research
Menu

Discover

GraphFollow connections around a paper, topic or saved view.

Workspaces

HomePick up where your research flow left off.InboxHandle requests, replies and notifications from one place.CollectionsCurate reading lists, evidence sets and shareable dossiers.ResearchSee your private provenance graph, trail and imports.CollaborationMove from discovery into focused discussion rooms.PublishDraft, preview and publish full-text research articles.

Network

ExpertsFind specialists worth following or asking for help.CommunitiesJoin research circles organized around shared work.PartnersSee external organizations active around the same topics.

Opportunities

ListingsBrowse roles, calls and collaborations with clearer fit signals.

Account

Log inReturn to your reading and collaboration workspace.Create accountStart saving work, following people and joining teams.
Log inCreate account

Researcher profile

Rene Werner

Rene Werner contributes to research discovery and scholarly infrastructure.

ResearcherAffiliation not importedOpen to collaborate
Computer Visioneess.IVArtificial IntelligenceMachine Learning

Trust snapshot

Quick read

Trust 13 - UnverifiedVerification L1Unclaimed author
2works
0followers
4topics
4close collaborators

Actions

Decide how to stay connected

Follow researcher0

Identity and collaboration

How to connect with this researcher

Claiming links this public author record to a researcher profile and unlocks direct collaboration workflows.

Log in to claim

Direct collaboration

Open a focused conversation when the fit is right

Claim this author entity first to unlock direct invitations.

Research graph

See the researcher in context

Open full explorer

Inspect adjacent work, topics, institutions and collaborators without jumping out to a separate graph page.

Building this graph slice

BZPEER is loading the nearby papers, people, topics and institutions for this page.

Published work

2 published item(s)

preprint2026arXiv

Layer Selection in Feature-Based Losses Affects Image Quality and Microstructural Consistency in Deep Learning Super-Resolution of Brain Diffusion MRI

Clinical application of high-resolution diffusion MRI is hindered by hardware limitations and prohibitive scan times, motivating computational super-resolution. This study investigates the efficacy of a feature-based loss function in preserving diffusion signal consistency in deep learning super-resolution. Using 7T data from the human connectome project to generate pairs of low- and high-resolution diffusion weighted images (DWI), we trained UNets for 2D super-resolution. Ablation and isolation studies evaluated different VGG16-layers for feature-based losses against an image-based L1 baseline. Deeper layers and combinations thereof resulted in grid-like artifacts in super-resolution DWIs, which persisted in diffusion parameters like quantitative and fractional anisotropy. No such artifacts were present when using the shallowest layer. Downstream analysis for this layer showed great consistency with the ground truth, even for 9-fold super-resolution. Image SNR and used VGG16-layer depths modulated artifact appearance and severity, mandating careful selection of contributing layers for application in and beyond diffusion MRI.

0 citations0 reviewsNo code linkedOpen access
preprint2025arXiv

MOIS-SAM2: Exemplar-based Segment Anything Model 2 for multilesion interactive segmentation of neurofibromas in whole-body MRI

Background and Objectives: Neurofibromatosis type 1 is a genetic disorder characterized by the development of numerous neurofibromas (NFs) throughout the body. Whole-body MRI (WB-MRI) is the clinical standard for detection and longitudinal surveillance of NF tumor growth. Existing interactive segmentation methods fail to combine high lesion-wise precision with scalability to hundreds of lesions. This study proposes a novel interactive segmentation model tailored to this challenge. Methods: We introduce MOIS-SAM2, a multi-object interactive segmentation model that extends the state-of-the-art, transformer-based, promptable Segment Anything Model 2 (SAM2) with exemplar-based semantic propagation. MOIS-SAM2 was trained and evaluated on 119 WB-MRI scans from 84 NF1 patients acquired using T2-weighted fat-suppressed sequences. The dataset was split at the patient level into a training set and four test sets (one in-domain and three reflecting different domain shift scenarios, e.g., MRI field strength variation, low tumor burden, differences in clinical site and scanner vendor). Results: On the in-domain test set, MOIS-SAM2 achieved a scan-wise DSC of 0.60 against expert manual annotations, outperforming baseline 3D nnU-Net (DSC: 0.54) and SAM2 (DSC: 0.35). Performance of the proposed model was maintained under MRI field strength shift (DSC: 0.53) and scanner vendor variation (DSC: 0.50), and improved in low tumor burden cases (DSC: 0.61). Lesion detection F1 scores ranged from 0.62 to 0.78 across test sets. Preliminary inter-reader variability analysis showed model-to-expert agreement (DSC: 0.62-0.68), comparable to inter-expert agreement (DSC: 0.57-0.69). Conclusions: The proposed MOIS-SAM2 enables efficient and scalable interactive segmentation of NFs in WB-MRI with minimal user input and strong generalization, supporting integration into clinical workflows.

0 citations0 reviewsNo code linkedOpen access