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Krishnaprasad Thirunarayan

Krishnaprasad Thirunarayan contributes to research discovery and scholarly infrastructure.

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Published work

9 published item(s)

preprint2026arXiv

Moral Sensitivity in LLMs: A Tiered Evaluation of Contextual Bias via Behavioral Profiling and Mechanistic Interpretability

Large language models (LLMs) are increasingly deployed in settings that require nuanced ethical reasoning, yet existing bias evaluations treat model outputs as simply "biased" or "unbiased." This binary framing misses the gradual, context-sensitive way bias actually emerges. We address this gap in two stages: behavioral profiling and mechanistic validation. In the behavioral stage, we introduce the Moral Sensitivity Index (MSI), a metric that quantifies the probability of biased output across a graduated, seven-tier stress test ranging from abstract numerical problems to scenarios rooted in historical and socioeconomic injustice. Evaluating four leading models (Claude 3.5, Qwen 3.5, Llama 3, and Gemini 1.5), we identify distinct behavioral signatures shaped by alignment design: for instance, Gemini 1.5 reaches 72.7% MSI by Tier 5 under socioeconomic framing, while Claude exhibits sharp suppression consistent with identity-based safety training. We then verify these behavioral patterns mechanistically. We select criminal-bias scenarios, which produced the highest MSI scores across models, as probes and apply logit lens, attention analysis, activation patching, and semantic probing to a controlled set of six models spanning three capability tiers: small language models (SLMs), instruction-tuned base models, and reasoning-distilled variants. Circuit-level analysis reveals a U-curve of bias: SLMs exhibit strong criminal bias; scaling to instruction-tuned models eliminates it; reasoning distillation reintroduces bias to SLM-like levels despite identical parameter counts, suggesting distillation compresses reasoning traces in ways that reactivate shallow statistical associations. Critically, the socially loaded cues that drive high MSI scores activate the same bias-driving circuits identified mechanistically, providing cross-stage validation.

preprint2022arXiv

Entity-driven Fact-aware Abstractive Summarization of Biomedical Literature

As part of the large number of scientific articles being published every year, the publication rate of biomedical literature has been increasing. Consequently, there has been considerable effort to harness and summarize the massive amount of biomedical research articles. While transformer-based encoder-decoder models in a vanilla source document-to-summary setting have been extensively studied for abstractive summarization in different domains, their major limitations continue to be entity hallucination (a phenomenon where generated summaries constitute entities not related to or present in source article(s)) and factual inconsistency. This problem is exacerbated in a biomedical setting where named entities and their semantics (which can be captured through a knowledge base) constitute the essence of an article. The use of named entities and facts mined from background knowledge bases pertaining to the named entities to guide abstractive summarization has not been studied in biomedical article summarization literature. In this paper, we propose an entity-driven fact-aware framework for training end-to-end transformer-based encoder-decoder models for abstractive summarization of biomedical articles. We call the proposed approach, whose building block is a transformer-based model, EFAS, Entity-driven Fact-aware Abstractive Summarization. We conduct experiments using five state-of-the-art transformer-based models (two of which are specifically designed for long document summarization) and demonstrate that injecting knowledge into the training/inference phase of these models enables the models to achieve significantly better performance than the standard source document-to-summary setting in terms of entity-level factual accuracy, N-gram novelty, and semantic equivalence while performing comparably on ROUGE metrics. The proposed approach is evaluated on ICD-11-Summ-1000, and PubMed-50k.

preprint2022arXiv

Improving the Factual Accuracy of Abstractive Clinical Text Summarization using Multi-Objective Optimization

While there has been recent progress in abstractive summarization as applied to different domains including news articles, scientific articles, and blog posts, the application of these techniques to clinical text summarization has been limited. This is primarily due to the lack of large-scale training data and the messy/unstructured nature of clinical notes as opposed to other domains where massive training data come in structured or semi-structured form. Further, one of the least explored and critical components of clinical text summarization is factual accuracy of clinical summaries. This is specifically crucial in the healthcare domain, cardiology in particular, where an accurate summary generation that preserves the facts in the source notes is critical to the well-being of a patient. In this study, we propose a framework for improving the factual accuracy of abstractive summarization of clinical text using knowledge-guided multi-objective optimization. We propose to jointly optimize three cost functions in our proposed architecture during training: generative loss, entity loss and knowledge loss and evaluate the proposed architecture on 1) clinical notes of patients with heart failure (HF), which we collect for this study; and 2) two benchmark datasets, Indiana University Chest X-ray collection (IU X-Ray), and MIMIC-CXR, that are publicly available. We experiment with three transformer encoder-decoder architectures and demonstrate that optimizing different loss functions leads to improved performance in terms of entity-level factual accuracy.

preprint2022arXiv

Leveraging Natural Learning Processing to Uncover Themes in Clinical Notes of Patients Admitted for Heart Failure

Heart failure occurs when the heart is not able to pump blood and oxygen to support other organs in the body as it should. Treatments include medications and sometimes hospitalization. Patients with heart failure can have both cardiovascular as well as non-cardiovascular comorbidities. Clinical notes of patients with heart failure can be analyzed to gain insight into the topics discussed in these notes and the major comorbidities in these patients. In this regard, we apply machine learning techniques, such as topic modeling, to identify the major themes found in the clinical notes specific to the procedures performed on 1,200 patients admitted for heart failure at the University of Illinois Hospital and Health Sciences System (UI Health). Topic modeling revealed five hidden themes in these clinical notes, including one related to heart disease comorbidities.

preprint2021arXiv

Predicting Early Indicators of Cognitive Decline from Verbal Utterances

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the earliest clinically detectable stage of incipient dementia, commonly known as mild cognitive impairment (MCI). Currently, these disorders are diagnosed using a manual analysis of neuropsychological examinations. We measure the feasibility of using the linguistic characteristics of verbal utterances elicited during neuropsychological exams of elderly subjects to distinguish between elderly control groups, people with MCI, people diagnosed with possible Alzheimer's disease (AD), and probable AD. We investigated the performance of both theory-driven psycholinguistic features and data-driven contextual language embeddings in identifying different clinically diagnosed groups. Our experiments show that a combination of contextual and psycholinguistic features extracted by a Support Vector Machine improved distinguishing the verbal utterances of elderly controls, people with MCI, possible AD, and probable AD. This is the first work to identify four clinical diagnosis groups of dementia in a highly imbalanced dataset. Our work shows that machine learning algorithms built on contextual and psycholinguistic features can learn the linguistic biomarkers from verbal utterances and assist clinical diagnosis of different stages and types of dementia, even with limited data.

preprint2020arXiv

A Practical Incremental Learning Framework For Sparse Entity Extraction

This work addresses challenges arising from extracting entities from textual data, including the high cost of data annotation, model accuracy, selecting appropriate evaluation criteria, and the overall quality of annotation. We present a framework that integrates Entity Set Expansion (ESE) and Active Learning (AL) to reduce the annotation cost of sparse data and provide an online evaluation method as feedback. This incremental and interactive learning framework allows for rapid annotation and subsequent extraction of sparse data while maintaining high accuracy. We evaluate our framework on three publicly available datasets and show that it drastically reduces the cost of sparse entity annotation by an average of 85% and 45% to reach 0.9 and 1.0 F-Scores respectively. Moreover, the method exhibited robust performance across all datasets.

preprint2020arXiv

Location Name Extraction from Targeted Text Streams using Gazetteer-based Statistical Language Models

Extracting location names from informal and unstructured social media data requires the identification of referent boundaries and partitioning compound names. Variability, particularly systematic variability in location names (Carroll, 1983), challenges the identification task. Some of this variability can be anticipated as operations within a statistical language model, in this case drawn from gazetteers such as OpenStreetMap (OSM), Geonames, and DBpedia. This permits evaluation of an observed n-gram in Twitter targeted text as a legitimate location name variant from the same location-context. Using n-gram statistics and location-related dictionaries, our Location Name Extraction tool (LNEx) handles abbreviations and automatically filters and augments the location names in gazetteers (handling name contractions and auxiliary contents) to help detect the boundaries of multi-word location names and thereby delimit them in texts. We evaluated our approach on 4,500 event-specific tweets from three targeted streams to compare the performance of LNEx against that of ten state-of-the-art taggers that rely on standard semantic, syntactic and/or orthographic features. LNEx improved the average F-Score by 33-179%, outperforming all taggers. Further, LNEx is capable of stream processing.

preprint2020arXiv

Measuring Pain in Sickle Cell Disease using Clinical Text

Sickle Cell Disease (SCD) is a hereditary disorder of red blood cells in humans. Complications such as pain, stroke, and organ failure occur in SCD as malformed, sickled red blood cells passing through small blood vessels get trapped. Particularly, acute pain is known to be the primary symptom of SCD. The insidious and subjective nature of SCD pain leads to challenges in pain assessment among Medical Practitioners (MPs). Thus, accurate identification of markers of pain in patients with SCD is crucial for pain management. Classifying clinical notes of patients with SCD based on their pain level enables MPs to give appropriate treatment. We propose a binary classification model to predict pain relevance of clinical notes and a multiclass classification model to predict pain level. While our four binary machine learning (ML) classifiers are comparable in their performance, Decision Trees had the best performance for the multiclass classification task achieving 0.70 in F-measure. Our results show the potential clinical text analysis and machine learning offer to pain management in sickle cell patients.

preprint2020arXiv

Towards Geocoding Spatial Expressions

Imprecise composite location references formed using ad hoc spatial expressions in English text makes the geocoding task challenging for both inference and evaluation. Typically such spatial expressions fill in unestablished areas with new toponyms for finer spatial referents. For example, the spatial extent of the ad hoc spatial expression "north of" or "50 minutes away from" in relation to the toponym "Dayton, OH" refers to an ambiguous, imprecise area, requiring translation from this qualitative representation to a quantitative one with precise semantics using systems such as WGS84. Here we highlight the challenges of geocoding such referents and propose a formal representation that employs background knowledge, semantic approximations and rules, and fuzzy linguistic variables. We also discuss an appropriate evaluation technique for the task that is based on human contextualized and subjective judgment.