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Researcher profile

Hui-Po Wang

Hui-Po Wang contributes to research discovery and scholarly infrastructure.

ResearcherAffiliation not importedOpen to collaborate
Computer VisionMachine Learning

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Published work

2 published item(s)

preprint2026arXiv

Automated Detection of Abnormalities in Zebrafish Development

Zebrafish embryos are a valuable model for drug discovery due to their optical transparency and genetic similarity to humans. However, current evaluations rely on manual inspection, which is costly and labor-intensive. While machine learning offers automation potential, progress is limited by the lack of comprehensive datasets. To address this, we introduce a large-scale dataset of high-resolution microscopic image sequences capturing zebrafish embryonic development under both control conditions and exposure to compounds (3,4-dichloroaniline). This dataset, with expert annotations at fine-grained temporal levels, supports two benchmarking tasks: (1) fertility classification, assessing zebrafish egg viability (130,368 images), and (2) toxicity assessment, detecting malformations induced by toxic exposure over time (55,296 images). Alongside the dataset, we present the first transformer-based baseline model that integrates spatiotemporal features to predict developmental abnormalities at early stages. Experimental results present the model's effectiveness, achieving 98% accuracy in fertility classification and 92% in toxicity assessment. These findings underscore the potential of automated approaches to enhance zebrafish-based toxicity analysis.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

CosSGD: Communication-Efficient Federated Learning with a Simple Cosine-Based Quantization

Federated learning is a promising framework to mitigate data privacy and computation concerns. However, the communication cost between the server and clients has become the major bottleneck for successful deployment. Despite notable progress in gradient compression, the existing quantization methods require further improvement when low-bits compression is applied, especially the overall systems often degenerate a lot when quantization are applied in double directions to compress model weights and gradients. In this work, we propose a simple cosine-based nonlinear quantization and achieve impressive results in compressing round-trip communication costs. We are not only able to compress model weights and gradients at higher ratios than previous methods, but also achieve competing model performance at the same time. Further, our approach is highly suitable for federated learning problems since it has low computational complexity and requires only a little additional data to recover the compressed information. Extensive experiments have been conducted on image classification and brain tumor semantic segmentation using the CIFAR-10, and BraTS datasets where we show state-of-the-art effectiveness and impressive communication efficiency.

0 citations0 reviewsNo code linkedOpen access