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Huan Song

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Machine Learning Artificial Intelligence Computation and Language Computer Vision

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preprint2026arXiv

Disentangling Shared and Task-Specific Representations from Multi-Modal Clinical Data

Real-world clinical data is inherently multimodal, providing complementary evidence that mirrors the practical necessity of jointly assessing multiple related outcomes. Although multi-task learning can improve efficiency by sharing information across outcomes, existing approaches often fail to balance shared representation learning with outcome-specific modeling. Hard parameter sharing can trigger negative transfer when task gradients conflict, while flexible sharing may still entangle shared and task-specific signals. To address this, we propose a multi-task framework built on a unified Transformer for multimodal fusion, augmented with Orthogonal Task Decomposition (OrthTD) to split patient representations into shared and task-specific subspaces and impose a geometric orthogonality constraint to reduce redundancy and isolate task-specific signals. We evaluated OrthTD on a real-world cohort of 12,430 surgical patients for predicting four outcomes. OrthTD achieved average AUC (area under the receiver operating characteristic curve) of 87.5% and average AUPRC (area under the precision-recall curve) of 37.2%, consistently outperformed advanced tabular and multi-task methods. Notably, OrthTD achieves substantial gains in AUPRC, indicating superior performance in identifying rare events within imbalanced clinical data. These results suggest that enforcing non-redundant shared and task-specific representations can improve multi-outcome prediction from multimodal clinical data.

preprint2023arXiv

Graph Neural Prompting with Large Language Models

Large language models (LLMs) have shown remarkable generalization capability with exceptional performance in various language modeling tasks. However, they still exhibit inherent limitations in precisely capturing and returning grounded knowledge. While existing work has explored utilizing knowledge graphs (KGs) to enhance language modeling via joint training and customized model architectures, applying this to LLMs is problematic owing to their large number of parameters and high computational cost. Therefore, how to enhance pre-trained LLMs using grounded knowledge, e.g., retrieval-augmented generation, remains an open question. In this work, we propose Graph Neural Prompting (GNP), a novel plug-and-play method to assist pre-trained LLMs in learning beneficial knowledge from KGs. GNP encompasses various designs, including a standard graph neural network encoder, a cross-modality pooling module, a domain projector, and a self-supervised link prediction objective. Extensive experiments on multiple datasets demonstrate the superiority of GNP on both commonsense and biomedical reasoning tasks across different LLM sizes and settings. Code is available at https://github.com/meettyj/GNP.

preprint2020arXiv

Improve Unsupervised Domain Adaptation with Mixup Training

Unsupervised domain adaptation studies the problem of utilizing a relevant source domain with abundant labels to build predictive modeling for an unannotated target domain. Recent work observe that the popular adversarial approach of learning domain-invariant features is insufficient to achieve desirable target domain performance and thus introduce additional training constraints, e.g. cluster assumption. However, these approaches impose the constraints on source and target domains individually, ignoring the important interplay between them. In this work, we propose to enforce training constraints across domains using mixup formulation to directly address the generalization performance for target data. In order to tackle potentially huge domain discrepancy, we further propose a feature-level consistency regularizer to facilitate the inter-domain constraint. When adding intra-domain mixup and domain adversarial learning, our general framework significantly improves state-of-the-art performance on several important tasks from both image classification and human activity recognition.

preprint2016arXiv

A Deep Learning Approach To Multiple Kernel Fusion

Kernel fusion is a popular and effective approach for combining multiple features that characterize different aspects of data. Traditional approaches for Multiple Kernel Learning (MKL) attempt to learn the parameters for combining the kernels through sophisticated optimization procedures. In this paper, we propose an alternative approach that creates dense embeddings for data using the kernel similarities and adopts a deep neural network architecture for fusing the embeddings. In order to improve the effectiveness of this network, we introduce the kernel dropout regularization strategy coupled with the use of an expanded set of composition kernels. Experiment results on a real-world activity recognition dataset show that the proposed architecture is effective in fusing kernels and achieves state-of-the-art performance.