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Gowtham Atluri

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Machine Learning Computational Engineering, Finance, and Science Cryptography and Security Genomics Molecular Networks

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preprint2026arXiv

Spectral Priors vs. Attention: Investigating the Utility of Attention Mechanisms in EEG-Based Diagnosis

Electroencephalograph (EEG) timeseries signals are characterized by significant noise and coarse spatial resolution, which complicates the classification of neurodegenerative diseases. Even SOTA deep learning architectures struggle to distinguish between healthy controls and diseased subjects, or between different disease types, due to high intergroup similarity. In this paper, we show that a spectrally selective approach to feature construction enhances class separability. By isolating signal strengths within the primary brainwave bands, we transform high dimensional raw data into high value spectral features. Our results demonstrate that a) features derived from frequency and time frequency domain allow traditional machine learning models to match or exceed the performance of SOTA deep learning models, b) Attention mechanism is unable to distill the stable feature signatures that characterize healthy neural activity in both resting and task EEGs, and c) the limitations of attention based models in finding relevant spectral features appear to be fundamental in that providing frequency selective time domain input do not appreciably improve their performance. We validate our methodology across three open source resting EEG datasets and one task EEG dataset, providing robust empirical evidence for our claims.

preprint2020arXiv

Fingerprinting Encrypted Voice Traffic on Smart Speakers with Deep Learning

This paper investigates the privacy leakage of smart speakers under an encrypted traffic analysis attack, referred to as voice command fingerprinting. In this attack, an adversary can eavesdrop both outgoing and incoming encrypted voice traffic of a smart speaker, and infers which voice command a user says over encrypted traffic. We first built an automatic voice traffic collection tool and collected two large-scale datasets on two smart speakers, Amazon Echo and Google Home. Then, we implemented proof-of-concept attacks by leveraging deep learning. Our experimental results over the two datasets indicate disturbing privacy concerns. Specifically, compared to 1% accuracy with random guess, our attacks can correctly infer voice commands over encrypted traffic with 92.89\% accuracy on Amazon Echo. Despite variances that human voices may cause on outgoing traffic, our proof-of-concept attacks remain effective even only leveraging incoming traffic (i.e., the traffic from the server). This is because the AI-based voice services running on the server side response commands in the same voice and with a deterministic or predictable manner in text, which leaves distinguishable pattern over encrypted traffic. We also built a proof-of-concept defense to obfuscate encrypted traffic. Our results show that the defense can effectively mitigate attack accuracy on Amazon Echo to 32.18%.

preprint2012arXiv

Enhancing the functional content of protein interaction networks

Protein interaction networks are a promising type of data for studying complex biological systems. However, despite the rich information embedded in these networks, they face important data quality challenges of noise and incompleteness that adversely affect the results obtained from their analysis. Here, we explore the use of the concept of common neighborhood similarity (CNS), which is a form of local structure in networks, to address these issues. Although several CNS measures have been proposed in the literature, an understanding of their relative efficacies for the analysis of interaction networks has been lacking. We follow the framework of graph transformation to convert the given interaction network into a transformed network corresponding to a variety of CNS measures evaluated. The effectiveness of each measure is then estimated by comparing the quality of protein function predictions obtained from its corresponding transformed network with those from the original network. Using a large set of S. cerevisiae interactions, and a set of 136 GO terms, we find that several of the transformed networks produce more accurate predictions than those obtained from the original network. In particular, the $HC.cont$ measure proposed here performs particularly well for this task. Further investigation reveals that the two major factors contributing to this improvement are the abilities of CNS measures, especially $HC.cont$, to prune out noisy edges and introduce new links between functionally related proteins.