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Fan Ma

Fan Ma contributes to research discovery and scholarly infrastructure.

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Artificial Intelligence Computer Vision Computation and Language Machine Learning eess.IV

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preprint2026arXiv

EHRNavigator: A Multi-Agent System for Patient-Level Clinical Question Answering over Heterogeneous Electronic Health Records

Clinical decision-making increasingly relies on timely and context-aware access to patient information within Electronic Health Records (EHRs), yet most existing natural language question-answering (QA) systems are evaluated solely on benchmark datasets, limiting their practical relevance. To overcome this limitation, we introduce EHRNavigator, a multi-agent framework that harnesses AI agents to perform patient-level question answering across heterogeneous and multimodal EHR data. We assessed its performance using both public benchmark and institutional datasets under realistic hospital conditions characterized by diverse schemas, temporal reasoning demands, and multimodal evidence integration. Through quantitative evaluation and clinician-validated chart review, EHRNavigator demonstrated strong generalization, achieving 86% accuracy on real-world cases while maintaining clinically acceptable response times. Overall, these findings confirm that EHRNavigator effectively bridges the gap between benchmark evaluation and clinical deployment, offering a robust, adaptive, and efficient solution for real-world EHR question answering.

preprint2026arXiv

Foundation Models to Unlock Real-World Evidence from Nationwide Medical Claims

Evidence derived from large-scale real-world data (RWD) is increasingly informing regulatory evaluation and healthcare decision-making. Administrative claims provide population-scale, longitudinal records of healthcare utilization, expenditure, and detailed coding of diagnoses, procedures, and medications, yet their potential as a substrate for healthcare foundation models remains largely unexplored. Here we present ReClaim, a generative transformer trained from scratch on 43.8 billion medical events from more than 200 million enrollees in the MarketScan claims data spanning 2008-2022. ReClaim models longitudinal trajectories across diagnoses, procedures, medications, and expenditure, and was scaled to 140 million, 700 million, and 1.7 billion parameters. Across over 1,000 disease-onset prediction tasks, ReClaim achieved a mean AUC of 75.6%, substantially outperforming disease-specific LightGBM (66.3%) and the transformer-based Delphi model (69.4%), with the largest gains for rare diseases. These advantages held across retrospective and prospective evaluations and in external validation on two independent datasets. Performance improved monotonically with scale, and post-training added 13.8 percentage points over pre-training alone. Beyond disease prediction, ReClaim captured financial outcomes and improved real-world evidence (RWE) analyses: for healthcare expenditure forecasting it increased explained variance from 0.28 to 0.37 relative to LightGBM, and in a target trial emulation it reduced systematic bias by 72% on average relative to Delphi. Together, these results establish administrative claims as a scalable substrate for healthcare foundation models and show that learned representations generalize across time periods and data sources, supporting disease surveillance, expenditure forecasting, and RWE generation.

preprint2026arXiv

TRACE: Temporal Routing with Autoregressive Cross-channel Experts for EEG Representation Learning

Learning transferable representations for electroencephalography (EEG) remains challenging because EEG signals are inherently multi-channel and non-stationary. Channels observed at the same time provide coupled measurements of neural activity, while the relevant temporal dynamics vary across contexts. This structure is poorly matched by architectures that apply uniform computation across time or route each channel patch independently. To this end, we propose TRACE, an autoregressive EEG pre-training framework that predicts future EEG patches from causal context while performing temporally adaptive and cross-channel coherent computation. At each temporal step, TRACE derives an expert routing decision from the causal cross-channel history and applies it jointly to all channels at that step. This preserves instantaneous cross-channel coherence while allowing different temporal regimes to activate different computation. Since routing is defined over the available channel set and causal temporal context, TRACE is compatible with heterogeneous pre-training across corpora with different channel counts, montages, sequence lengths, and recording domains. Across eight downstream EEG benchmarks, TRACE is evaluated in both settings: when downstream domains are seen only as unlabeled pre-training data and when downstream datasets are completely unseen during pre-training. It obtains the best results on several benchmarks while remaining competitive on motor imagery and clinical event classification tasks, with ablations supporting the importance of cross-channel temporal routing.

preprint2023arXiv

Temporal Perceiving Video-Language Pre-training

Video-Language Pre-training models have recently significantly improved various multi-modal downstream tasks. Previous dominant works mainly adopt contrastive learning to achieve global feature alignment across modalities. However, the local associations between videos and texts are not modeled, restricting the pre-training models' generality, especially for tasks requiring the temporal video boundary for certain query texts. This work introduces a novel text-video localization pre-text task to enable fine-grained temporal and semantic alignment such that the trained model can accurately perceive temporal boundaries in videos given the text description. Specifically, text-video localization consists of moment retrieval, which predicts start and end boundaries in videos given the text description, and text localization which matches the subset of texts with the video features. To produce temporal boundaries, frame features in several videos are manually merged into a long video sequence that interacts with a text sequence. With the localization task, our method connects the fine-grained frame representations with the word representations and implicitly distinguishes representations of different instances in the single modality. Notably, comprehensive experimental results show that our method significantly improves the state-of-the-art performance on various benchmarks, covering text-to-video retrieval, video question answering, video captioning, temporal action localization and temporal moment retrieval. The code will be released soon.

preprint2022arXiv

Unified Transformer Tracker for Object Tracking

As an important area in computer vision, object tracking has formed two separate communities that respectively study Single Object Tracking (SOT) and Multiple Object Tracking (MOT). However, current methods in one tracking scenario are not easily adapted to the other due to the divergent training datasets and tracking objects of both tasks. Although UniTrack \cite{wang2021different} demonstrates that a shared appearance model with multiple heads can be used to tackle individual tracking tasks, it fails to exploit the large-scale tracking datasets for training and performs poorly on single object tracking. In this work, we present the Unified Transformer Tracker (UTT) to address tracking problems in different scenarios with one paradigm. A track transformer is developed in our UTT to track the target in both SOT and MOT. The correlation between the target and tracking frame features is exploited to localize the target. We demonstrate that both SOT and MOT tasks can be solved within this framework. The model can be simultaneously end-to-end trained by alternatively optimizing the SOT and MOT objectives on the datasets of individual tasks. Extensive experiments are conducted on several benchmarks with a unified model trained on SOT and MOT datasets. Code will be available at https://github.com/Flowerfan/Trackron.

preprint2020arXiv

SF-Net: Single-Frame Supervision for Temporal Action Localization

In this paper, we study an intermediate form of supervision, i.e., single-frame supervision, for temporal action localization (TAL). To obtain the single-frame supervision, the annotators are asked to identify only a single frame within the temporal window of an action. This can significantly reduce the labor cost of obtaining full supervision which requires annotating the action boundary. Compared to the weak supervision that only annotates the video-level label, the single-frame supervision introduces extra temporal action signals while maintaining low annotation overhead. To make full use of such single-frame supervision, we propose a unified system called SF-Net. First, we propose to predict an actionness score for each video frame. Along with a typical category score, the actionness score can provide comprehensive information about the occurrence of a potential action and aid the temporal boundary refinement during inference. Second, we mine pseudo action and background frames based on the single-frame annotations. We identify pseudo action frames by adaptively expanding each annotated single frame to its nearby, contextual frames and we mine pseudo background frames from all the unannotated frames across multiple videos. Together with the ground-truth labeled frames, these pseudo-labeled frames are further used for training the classifier. In extensive experiments on THUMOS14, GTEA, and BEOID, SF-Net significantly improves upon state-of-the-art weakly-supervised methods in terms of both segment localization and single-frame localization. Notably, SF-Net achieves comparable results to its fully-supervised counterpart which requires much more resource intensive annotations. The code is available at https://github.com/Flowerfan/SF-Net.

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