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Chuang Zhu

Chuang Zhu contributes to research discovery and scholarly infrastructure.

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Computer Vision eess.IV Artificial Intelligence Machine Learning physics.med-ph

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preprint2026arXiv

DSAA: Dual-Stage Attribute Activation for Fine-grained Open Vocabulary Detection

Open-Vocabulary Object Detection (OVD) models break the limitations of closed-set detection, enabling the iden- tification of unseen categories through natural language prompts. However, they exhibit notable limitations in fine- grained detection tasks involving attributes like color, ma- terial, and texture. We attribute this performance bottle- neck in OVD models to a core issue: when category sig- nals dominate, OVD models tend to marginalize attribute information during inference. This leads to incorrect bind- ing between attributes and target objects. To address this, we propose the Dual-Stage Attribute Activation (DSAA) framework, which enhances fine-grained detection capa- bilities by strengthening attribute semantics at two criti- cal stages. In the text embedding stage, we employ At- tribute Prefix Adapter (APA) module to generate attribute prefixes that inject explicit attribute priors. To further am- plify the influence of these attributes, our Key/Value (K/V) Modulator module then intervenes during the BERT encod- ing phase, selectively enhancing the Key and Value vec- tors of the corresponding attribute tokens. In addition, we introduce an attribute-aware contrastive loss to improve discrimination among same-category instances with differ- ent attributes during training. Experimental results on the FG-OVD benchmark demonstrate the effectiveness of our method across various mainstream open-vocabulary mod- els.

preprint2026arXiv

RE-VLM: Event-Augmented Vision-Language Model for Scene Understanding

Conventional vision-language models (VLMs) struggle to interpret scenes captured under adverse conditions (e.g., low light, high dynamic range, or fast motion) because standard RGB images degrade in such environments. Event cameras provide a complementary modality: they asynchronously record per-pixel brightness changes with high temporal resolution and wide dynamic range, preserving motion cues where frames fail. We propose RE-VLM, the first dual-stream vision-language model that jointly leverages RGB images and event streams for robust scene understanding across both normal and challenging conditions. RE-VLM employs parallel RGB and event encoders together with a progressive training strategy that aligns heterogeneous visual features with language. To address the scarcity of RGB-Event-Text supervision, we further propose a graph-driven pipeline that converts synchronized RGB-Event streams into verifiable scene graphs, from which we synthesize captions and question-answer (QA) pairs. To develop and evaluate RE-VLM, we construct two datasets: PEOD-Chat, targeting illumination-challenged scenes, and RGBE-Chat, covering diverse scenarios. On captioning and VQA benchmarks, RE-VLM consistently outperforms state-of-the-art RGB-only and event-only models with comparable parameter counts, with particularly large gains under challenging conditions. These results demonstrate the effectiveness of event-augmented VLMs in achieving robust vision-language understanding across a wide range of real-world environments. Code and datasets are available at https://github.com/bupt-ai-cz/RE-VLM.

preprint2022arXiv

BCI: Breast Cancer Immunohistochemical Image Generation through Pyramid Pix2pix

The evaluation of human epidermal growth factor receptor 2 (HER2) expression is essential to formulate a precise treatment for breast cancer. The routine evaluation of HER2 is conducted with immunohistochemical techniques (IHC), which is very expensive. Therefore, for the first time, we propose a breast cancer immunohistochemical (BCI) benchmark attempting to synthesize IHC data directly with the paired hematoxylin and eosin (HE) stained images. The dataset contains 4870 registered image pairs, covering a variety of HER2 expression levels. Based on BCI, as a minor contribution, we further build a pyramid pix2pix image generation method, which achieves better HE to IHC translation results than the other current popular algorithms. Extensive experiments demonstrate that BCI poses new challenges to the existing image translation research. Besides, BCI also opens the door for future pathology studies in HER2 expression evaluation based on the synthesized IHC images. BCI dataset can be downloaded from https://bupt-ai-cz.github.io/BCI.

preprint2022arXiv

Hard-sample Guided Hybrid Contrast Learning for Unsupervised Person Re-Identification

Unsupervised person re-identification (Re-ID) is a promising and very challenging research problem in computer vision. Learning robust and discriminative features with unlabeled data is of central importance to Re-ID. Recently, more attention has been paid to unsupervised Re-ID algorithms based on clustered pseudo-label. However, the previous approaches did not fully exploit information of hard samples, simply using cluster centroid or all instances for contrastive learning. In this paper, we propose a Hard-sample Guided Hybrid Contrast Learning (HHCL) approach combining cluster-level loss with instance-level loss for unsupervised person Re-ID. Our approach applies cluster centroid contrastive loss to ensure that the network is updated in a more stable way. Meanwhile, introduction of a hard instance contrastive loss further mines the discriminative information. Extensive experiments on two popular large-scale Re-ID benchmarks demonstrate that our HHCL outperforms previous state-of-the-art methods and significantly improves the performance of unsupervised person Re-ID. The code of our work is available soon at https://github.com/bupt-ai-cz/HHCL-ReID.

preprint2022arXiv

Predicting Axillary Lymph Node Metastasis in Early Breast Cancer Using Deep Learning on Primary Tumor Biopsy Slides

Objectives: To develop and validate a deep learning (DL)-based primary tumor biopsy signature for predicting axillary lymph node (ALN) metastasis preoperatively in early breast cancer (EBC) patients with clinically negative ALN. Methods: A total of 1,058 EBC patients with pathologically confirmed ALN status were enrolled from May 2010 to August 2020. A DL core-needle biopsy (DL-CNB) model was built on the attention-based multiple instance-learning (AMIL) framework to predict ALN status utilizing the DL features, which were extracted from the cancer areas of digitized whole-slide images (WSIs) of breast CNB specimens annotated by two pathologists. Accuracy, sensitivity, specificity, receiver operating characteristic (ROC) curves, and areas under the ROC curve (AUCs) were analyzed to evaluate our model. Results: The best-performing DL-CNB model with VGG16_BN as the feature extractor achieved an AUC of 0.816 (95% confidence interval (CI): 0.758, 0.865) in predicting positive ALN metastasis in the independent test cohort. Furthermore, our model incorporating the clinical data, which was called DL-CNB+C, yielded the best accuracy of 0.831 (95%CI: 0.775, 0.878), especially for patients younger than 50 years (AUC: 0.918, 95%CI: 0.825, 0.971). The interpretation of DL-CNB model showed that the top signatures most predictive of ALN metastasis were characterized by the nucleus features including density ($p$ = 0.015), circumference ($p$ = 0.009), circularity ($p$ = 0.010), and orientation ($p$ = 0.012). Conclusion: Our study provides a novel DL-based biomarker on primary tumor CNB slides to predict the metastatic status of ALN preoperatively for patients with EBC. The codes and dataset are available at https://github.com/bupt-ai-cz/BALNMP

preprint2022arXiv

Sample Prior Guided Robust Model Learning to Suppress Noisy Labels

Imperfect labels are ubiquitous in real-world datasets and seriously harm the model performance. Several recent effective methods for handling noisy labels have two key steps: 1) dividing samples into cleanly labeled and wrongly labeled sets by training loss, 2) using semi-supervised methods to generate pseudo-labels for samples in the wrongly labeled set. However, current methods always hurt the informative hard samples due to the similar loss distribution between the hard samples and the noisy ones. In this paper, we proposed PGDF (Prior Guided Denoising Framework), a novel framework to learn a deep model to suppress noise by generating the samples' prior knowledge, which is integrated into both dividing samples step and semi-supervised step. Our framework can save more informative hard clean samples into the cleanly labeled set. Besides, our framework also promotes the quality of pseudo-labels during the semi-supervised step by suppressing the noise in the current pseudo-labels generating scheme. To further enhance the hard samples, we reweight the samples in the cleanly labeled set during training. We evaluated our method using synthetic datasets based on CIFAR-10 and CIFAR-100, as well as on the real-world datasets WebVision and Clothing1M. The results demonstrate substantial improvements over state-of-the-art methods.

preprint2020arXiv

Cross-stained Segmentation from Renal Biopsy Images Using Multi-level Adversarial Learning

Segmentation from renal pathological images is a key step in automatic analyzing the renal histological characteristics. However, the performance of models varies significantly in different types of stained datasets due to the appearance variations. In this paper, we design a robust and flexible model for cross-stained segmentation. It is a novel multi-level deep adversarial network architecture that consists of three sub-networks: (i) a segmentation network; (ii) a pair of multi-level mirrored discriminators for guiding the segmentation network to extract domain-invariant features; (iii) a shape discriminator that is utilized to further identify the output of the segmentation network and the ground truth. Experimental results on glomeruli segmentation from renal biopsy images indicate that our network is able to improve segmentation performance on target type of stained images and use unlabeled data to achieve similar accuracy to labeled data. In addition, this method can be easily applied to other tasks.

preprint2020arXiv

Instance Adaptive Self-Training for Unsupervised Domain Adaptation

The divergence between labeled training data and unlabeled testing data is a significant challenge for recent deep learning models. Unsupervised domain adaptation (UDA) attempts to solve such a problem. Recent works show that self-training is a powerful approach to UDA. However, existing methods have difficulty in balancing scalability and performance. In this paper, we propose an instance adaptive self-training framework for UDA on the task of semantic segmentation. To effectively improve the quality of pseudo-labels, we develop a novel pseudo-label generation strategy with an instance adaptive selector. Besides, we propose the region-guided regularization to smooth the pseudo-label region and sharpen the non-pseudo-label region. Our method is so concise and efficient that it is easy to be generalized to other unsupervised domain adaptation methods. Experiments on 'GTA5 to Cityscapes' and 'SYNTHIA to Cityscapes' demonstrate the superior performance of our approach compared with the state-of-the-art methods.

preprint2020arXiv

Multi-level colonoscopy malignant tissue detection with adversarial CAC-UNet

The automatic and objective medical diagnostic model can be valuable to achieve early cancer detection, and thus reducing the mortality rate. In this paper, we propose a highly efficient multi-level malignant tissue detection through the designed adversarial CAC-UNet. A patch-level model with a pre-prediction strategy and a malignancy area guided label smoothing is adopted to remove the negative WSIs, with which to lower the risk of false positive detection. For the selected key patches by multi-model ensemble, an adversarial context-aware and appearance consistency UNet (CAC-UNet) is designed to achieve robust segmentation. In CAC-UNet, mirror designed discriminators are able to seamlessly fuse the whole feature maps of the skillfully designed powerful backbone network without any information loss. Besides, a mask prior is further added to guide the accurate segmentation mask prediction through an extra mask-domain discriminator. The proposed scheme achieves the best results in MICCAI DigestPath2019 challenge on colonoscopy tissue segmentation and classification task. The full implementation details and the trained models are available at https://github.com/Raykoooo/CAC-UNet.

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