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Brian P. Williams

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quant-ph Artificial Intelligence Networking and Internet Architecture physics.optics

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preprint2026arXiv

Prospective multi-pathogen disease forecasting using autonomous LLM-guided tree search

Probabilistic forecasting of infectious diseases is crucial for public health but relies on labor-intensive manual model curation by expert modeling teams. This bespoke development bottlenecks scalability to granular geographic resolutions or emerging pathogens. Here, we present an autonomous system using Large Language Model (LLM)-guided tree search to iteratively generate, evaluate, and optimize executable forecasting software. In a fully prospective, real-time evaluation during the 2025-2026 US respiratory season, the system autonomously discovered methodologically diverse models for influenza, COVID-19, and respiratory syncytial virus (RSV). Aggregating these machine-generated models yielded an ensemble that consistently matched or outperformed the gold-standard, human-curated Centers for Disease Control and Prevention (CDC) hub ensembles out-of-sample. The system successfully navigated data-scarce "cold start" scenarios for RSV. Moreover, controlled retrospective ablations revealed that optimizing log-scale distance metrics prevents reward hacking, while an automated judge-in-the-loop ensures structural fidelity to complex scientific theories. By autonomously translating epidemiological theory into accurate, transparent code, this framework overcomes the modeling labor bottleneck, enabling rapid deployment of expert-level disease forecasting at unprecedented scales.

preprint2021arXiv

Advanced Architectures for High-Performance Quantum Networking

As practical quantum networks prepare to serve an ever-expanding number of nodes, there has grown a need for advanced auxiliary classical systems that support the quantum protocols and maintain compatibility with the existing fiber-optic infrastructure. We propose and demonstrate a quantum local area network design that addresses current deployment limitations in timing and security in a scalable fashion using commercial off-the-shelf components. We employ White Rabbit switches to synchronize three remote nodes with ultra-low timing jitter, significantly increasing the fidelities of the distributed entangled states over previous work with Global Positioning System clocks. Second, using a parallel quantum key distribution channel, we secure the classical communications needed for instrument control and data management. In this way, the conventional network which manages our entanglement network is secured using keys generated via an underlying quantum key distribution layer, preserving the integrity of the supporting systems and the relevant data in a future-proof fashion.

preprint2021arXiv

Lessons Learned on the Interface between Quantum and Conventional Networking

The future Quantum Internet is expected to be based on a hybrid architecture with core quantum transport capabilities complemented by conventional networking.Practical and foundational considerations indicate the need for conventional control and data planes that (i) utilize extensive existing telecommunications fiber infrastructure, and (ii) provide parallel conventional data channels needed for quantum networking protocols. We propose a quantum-conventional network (QCN) harness to implement a new architecture to meet these requirements. The QCN control plane carries the control and management traffic, whereas its data plane handles the conventional and quantum data communications. We established a local area QCN connecting three quantum laboratories over dedicated fiber and conventional network connections. We describe considerations and tradeoffs for layering QCN functionalities, informed by our recent quantum entanglement distribution experiments conducted over this network.

preprint2020arXiv

Experimental passive state preparation for continuous variable quantum communications

In the Gaussian-modulated coherent state quantum key distribution (QKD) protocol, the sender first generates Gaussian distributed random numbers and then encodes them on weak laser pulses actively by performing amplitude and phase modulations. Recently, an equivalent passive QKD scheme was proposed by exploring the intrinsic field fluctuations of a thermal source [B. Qi, P. G. Evans, and W. P. Grice, Phys. Rev. A 97, 012317 (2018)]. This passive QKD scheme is especially appealing for chip-scale implementation since no active modulations are required. In this paper, we conduct an experimental study of the passively encoded QKD scheme using an off-the-shelf amplified spontaneous emission source operated in continuous-wave mode. Our results show that the excess noise introduced by the passive state preparation scheme can be effectively suppressed by applying optical attenuation and secure key could be generated over metro-area distances.

preprint2019arXiv

Characterizing photon number statistics using conjugate optical homodyne detection

We study the problem of determining the photon number statistics of an unknown quantum state by simultaneously measuring conjugate quadratures with double homodyne detectors. Classically, the sum of the squared outputs of the two homodyne detectors is proportional to the intensity (thus the photon number) of the input light. Quantum mechanically, due to vacuum noise, the above photon number measurement is intrinsically noisy. We quantify the information gain in a single-shot measurement and discuss potential applications of this technology in quantum key distribution. We also show that the photon number statistics can be recovered in repeated measurements on an ensemble of identical input states without scanning the phase of the input state or randomizing the phase of the local oscillator used in homodyne detection.

preprint2016arXiv

Programmable Multi-Node Quantum Network Design and Simulation

Software-defined networking offers a device-agnostic programmable framework to encode new network functions. Externally centralized control plane intelligence allows programmers to write network applications and to build functional network designs. OpenFlow is a key protocol widely adopted to build programmable networks because of its programmability, flexibility and ability to interconnect heterogeneous network devices. We simulate the functional topology of a multi-node quantum network that uses programmable network principles to manage quantum metadata for protocols such as teleportation, superdense coding, and quantum key distribution. We first show how the OpenFlow protocol can manage the quantum metadata needed to control the quantum channel. We then use numerical simulation to demonstrate robust programmability of a quantum switch via the OpenFlow network controller while executing an application of superdense coding. We describe the software framework implemented to carry out these simulations and we discuss near-term efforts to realize these applications.

preprint2015arXiv

A tamper-indicating quantum seal

Technical means for identifying when tampering occurs is a critical part of many containment and surveillance technologies. Conventional fiber optic seals provide methods for monitoring enclosed inventories, but they are vulnerable to spoofing attacks based on classical physics. We address these vulnerabilities with the development of a quantum seal that offers the ability to detect the intercept-resend attack using quantum integrity verification. Our approach represents an application of entanglement to provide guarantees in the authenticity of the seal state by verifying it was transmitted coherently. We implement these ideas using polarization-entangled photon pairs that are verified after passing through a fiber-optic channel testbed. Using binary detection theory, we find the probability of detecting inauthentic signals is greater than 0.9999 with a false alarm chance of $10^{-9}$ for a 10 second sampling interval. In addition, we show how the Hong-Ou-Mandel effect concurrently provides a tight bound on redirection attack, in which tampering modifies the shape of the seal. Our measurements limit the tolerable path length change to sub-millimeter disturbances. These tamper-indicating features of the quantum seal offer unprecedented security for unattended monitoring systems.

preprint2015arXiv

Efficient two-photon polarization entanglement detection by Bell state analysis

We emphasize the Bell state analyzer, a beamsplitter, as an efficient means of detecting two-photon polarization entanglement. Whereas the optimal entanglement witness for spatially separated photons requires coordinated measurement in three bases, the local Bell state analyzer enables an efficient entanglement witness in a single polarization basis. We use Bayesian mean estimation to compare the efficiency of these two witnesses. We report the method and results of this comparison.

preprint2014arXiv

A nonlocal polarization interferometer for entanglement detection

We report a nonlocal interferometer capable of detecting entanglement and identifying Bell states statistically. This is possible due to the interferometer's unique correlation dependence on the anti-diagonal elements of the density matrix, which have distinct bounds for separable states and unique values for the four Bell states. The interferometer consists of two spatially separated balanced Mach-Zehnder or Sagnac interferometers that share a polarization entangled source. Correlations between these interferometers exhibit non-local interference, while single photon interference is suppressed. This interferometer also allows for a unique version of the CHSH-Bell test where the local reality is the photon polarization. We present the relevant theory and experimental results.

preprint2013arXiv

Quantum-Secured Surveillance Based on Mach-Zehnder Interferometry

We present a method for intrusion detection which is based on the Mach-Zehnder interference effect. This device provides monitored surveillance by continuously measuring the intensity of light collected by a pair of photodetectors. We find that our protocol allows for the detection of intrusion attempts which employ path- redirection and/or intercept-resend techniques. Expectation values for the registered output flux are provided for normal and interrupted operation.