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Anna Goldenberg

Anna Goldenberg contributes to research discovery and scholarly infrastructure.

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Published work

5 published item(s)

preprint2026arXiv

LiBaGS: Lightweight Boundary Gap Synthesis for Targeted Synthetic Data Selection

Synthetic data is useful only when the added samples fill missing parts of the training distribution that matter for the downstream task. We introduce LiBaGS, a lightweight, generator-agnostic method for targeted synthetic training data selection. LiBaGS scores candidate synthetic samples by combining decision-boundary proximity, predictive uncertainty, real-data density, and support validity, so that selected samples are both informative and likely to remain on the real data manifold. We then use a boundary-gap allocation rule that targets sparse but realistic decision-boundary neighborhoods, rather than simply adding more data or selecting only the most uncertain candidates. LiBaGS also learns when enough synthetic samples have been added through a marginal-value stopping rule, assigns softer labels near ambiguous boundaries, and uses a diversity objective to avoid redundant near-duplicate selections. Experiments show that LiBaGS improves accuracy over classical oversampling, hard augmentation, uncertainty and density ablations, and targeted-generation selection criteria.

preprint2022arXiv

Decoupling Local and Global Representations of Time Series

Real-world time series data are often generated from several sources of variation. Learning representations that capture the factors contributing to this variability enables a better understanding of the data via its underlying generative process and improves performance on downstream machine learning tasks. This paper proposes a novel generative approach for learning representations for the global and local factors of variation in time series. The local representation of each sample models non-stationarity over time with a stochastic process prior, and the global representation of the sample encodes the time-independent characteristics. To encourage decoupling between the representations, we introduce counterfactual regularization that minimizes the mutual information between the two variables. In experiments, we demonstrate successful recovery of the true local and global variability factors on simulated data, and show that representations learned using our method yield superior performance on downstream tasks on real-world datasets. We believe that the proposed way of defining representations is beneficial for data modelling and yields better insights into the complexity of real-world data.

preprint2022arXiv

NODE-GAM: Neural Generalized Additive Model for Interpretable Deep Learning

Deployment of machine learning models in real high-risk settings (e.g. healthcare) often depends not only on the model's accuracy but also on its fairness, robustness, and interpretability. Generalized Additive Models (GAMs) are a class of interpretable models with a long history of use in these high-risk domains, but they lack desirable features of deep learning such as differentiability and scalability. In this work, we propose a neural GAM (NODE-GAM) and neural GA$^2$M (NODE-GA$^2$M) that scale well and perform better than other GAMs on large datasets, while remaining interpretable compared to other ensemble and deep learning models. We demonstrate that our models find interesting patterns in the data. Lastly, we show that we improve model accuracy via self-supervised pre-training, an improvement that is not possible for non-differentiable GAMs.

preprint2020arXiv

A Comprehensive Evaluation of Multi-task Learning and Multi-task Pre-training on EHR Time-series Data

Multi-task learning (MTL) is a machine learning technique aiming to improve model performance by leveraging information across many tasks. It has been used extensively on various data modalities, including electronic health record (EHR) data. However, despite significant use on EHR data, there has been little systematic investigation of the utility of MTL across the diverse set of possible tasks and training schemes of interest in healthcare. In this work, we examine MTL across a battery of tasks on EHR time-series data. We find that while MTL does suffer from common negative transfer, we can realize significant gains via MTL pre-training combined with single-task fine-tuning. We demonstrate that these gains can be achieved in a task-independent manner and offer not only minor improvements under traditional learning, but also notable gains in a few-shot learning context, thereby suggesting this could be a scalable vehicle to offer improved performance in important healthcare contexts.

preprint2020arXiv

Using Generative Models for Pediatric wbMRI

Early detection of cancer is key to a good prognosis and requires frequent testing, especially in pediatrics. Whole-body magnetic resonance imaging (wbMRI) is an essential part of several well-established screening protocols, with screening starting in early childhood. To date, machine learning (ML) has been used on wbMRI images to stage adult cancer patients. It is not possible to use such tools in pediatrics due to the changing bone signal throughout growth, the difficulty of obtaining these images in young children due to movement and limited compliance, and the rarity of positive cases. We evaluate the quality of wbMRI images generated using generative adversarial networks (GANs) trained on wbMRI data from The Hospital for Sick Children in Toronto. We use the Frchet Inception Distance (FID) metric, Domain Frchet Distance (DFD), and blind tests with a radiology fellow for evaluation. We demonstrate that StyleGAN2 provides the best performance in generating wbMRI images with respect to all three metrics.