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Alexander Effland

Alexander Effland contributes to research discovery and scholarly infrastructure.

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Published work

5 published item(s)

preprint2026arXiv

Uncertainty Quantification for Cardiac Shape Reconstruction with Deep Signed Distance Functions via MCMC methods

Atlas-based approaches allow high-quality, patient-specific shape reconstructions of cardiac anatomy from sparse and/or noisy data such as point clouds. However, these methods are mainly prior-driven, so the impact of uncertainty can be large, limiting their clinical reliability. We propose a probabilistic framework for uncertainty-aware cardiac shape reconstruction that combines Deep Signed Distance Functions (DeepSDFs) with Markov Chain Monte Carlo (MCMC) sampling. Cardiac geometries are modeled implicitly as zero-level sets of a neural network conditioned on learned latent codes, enabling multi-surface reconstruction of the left and right ventricles. By interpreting the reconstruction loss as a log-likelihood, we perform Bayesian inference in the latent space to obtain both maximum a posteriori (MAP) and posterior-sampled reconstructions. Experiments on a public cardiac dataset show that our approach produces accurate reconstructions and well-calibrated uncertainty estimates.

preprint2020arXiv

Convergence of the Time Discrete Metamorphosis Model on Hadamard Manifolds

Continuous image morphing is a classical task in image processing. The metamorphosis model proposed by Trouvé, Younes and coworkers casts this problem in the frame of Riemannian geometry and geodesic paths between images. The associated metric in the space of images incorporates dissipation caused by a viscous flow transporting image intensities and its variations along motion paths. In many applications, images are maps from the image domain into a manifold (e.g. in diffusion tensor imaging (DTI) the manifold of symmetric positive definite matrices with a suitable Riemannian metric). In this paper, we propose a generalized metamorphosis model for manifold-valued images, where the range space is a finite-dimensional Hadamard manifold. A corresponding time discrete version was presented by Neumayer et al. based on the general variational time discretization proposed by Berkels et al. Here, we prove the Mosco--convergence of the time discrete metamorphosis functional to the proposed manifold-valued metamorphosis model, which implies the convergence of time discrete geodesic paths to a geodesic path in the (time continuous) metamorphosis model. In particular, the existence of geodesic paths is established. In fact, images as maps into Hadamard manifold are not only relevant in applications, but it is also shown that the joint convexity of the distance function which characterizes Hadamard manifolds is a crucial ingredient to establish existence of the metamorphosis model.

preprint2020arXiv

Image Morphing in Deep Feature Spaces: Theory and Applications

This paper combines image metamorphosis with deep features. To this end, images are considered as maps into a high-dimensional feature space and a structure-sensitive, anisotropic flow regularization is incorporated in the metamorphosis model proposed by Miller, Trouvé, Younes and coworkers. For this model a variational time discretization of the Riemannian path energy is presented and the existence of discrete geodesic paths minimizing this energy is demonstrated. Furthermore, convergence of discrete geodesic paths to geodesic paths in the time continuous model is investigated. The spatial discretization is based on a finite difference approximation in image space and a stable spline approximation in deformation space, the fully discrete model is optimized using the iPALM algorithm. Numerical experiments indicate that the incorporation of semantic deep features is superior to intensity-based approaches.

preprint2020arXiv

Total Deep Variation for Linear Inverse Problems

Diverse inverse problems in imaging can be cast as variational problems composed of a task-specific data fidelity term and a regularization term. In this paper, we propose a novel learnable general-purpose regularizer exploiting recent architectural design patterns from deep learning. We cast the learning problem as a discrete sampled optimal control problem, for which we derive the adjoint state equations and an optimality condition. By exploiting the variational structure of our approach, we perform a sensitivity analysis with respect to the learned parameters obtained from different training datasets. Moreover, we carry out a nonlinear eigenfunction analysis, which reveals interesting properties of the learned regularizer. We show state-of-the-art performance for classical image restoration and medical image reconstruction problems.

preprint2020arXiv

Total Deep Variation: A Stable Regularizer for Inverse Problems

Various problems in computer vision and medical imaging can be cast as inverse problems. A frequent method for solving inverse problems is the variational approach, which amounts to minimizing an energy composed of a data fidelity term and a regularizer. Classically, handcrafted regularizers are used, which are commonly outperformed by state-of-the-art deep learning approaches. In this work, we combine the variational formulation of inverse problems with deep learning by introducing the data-driven general-purpose total deep variation regularizer. In its core, a convolutional neural network extracts local features on multiple scales and in successive blocks. This combination allows for a rigorous mathematical analysis including an optimal control formulation of the training problem in a mean-field setting and a stability analysis with respect to the initial values and the parameters of the regularizer. In addition, we experimentally verify the robustness against adversarial attacks and numerically derive upper bounds for the generalization error. Finally, we achieve state-of-the-art results for numerous imaging tasks.